Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Bicycle Therapeutics PLC as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 105
- +4 vs. Q4 2021
- Shares held
- 20.2M
- −1.39M (−6.5%) vs. Q4 2021
- Total value
- $884.5M
- −$427.4M (−32.6%) vs. Q4 2021
- New holders
- 24
- 27 more added
- Sold out
- 20
- 42 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Deep Track Capital, LP | 1,855,993 | $81.4M | 5.26% | +755,993+68.7% | Added |
| Janus Henderson Group PLC | 1,692,774 | $74.3M | 0.04% | −2,635−0.2% | Reduced |
| Point72 Asset Management, L.P. | 1,619,802 | $71.1M | 0.31% | +46,979+3.0% | Added |
| RTW Investments, LP | 1,276,276 | $56.0M | 1.16% | +407,005+46.8% | Added |
| Eventide Asset Management, LLC | 1,263,471 | $55.4M | 0.87% | 00.0% | Unchanged |
| Tybourne Capital Management (HK) Ltd | 1,154,126 | $50.6M | 3.00% | −899,678−43.8% | Reduced |
| Logos Global Management LP | 950,000 | $41.7M | 5.40% | +80,000+9.2% | Added |
| SV Health Investors, LLC | 917,218 | $40.2M | 48.61% | −936−0.1% | Reduced |
| First Light Asset Management, LLC | 890,174 | $39.1M | 3.45% | −110,609−11.1% | Reduced |
| FMR LLC | 803,748 | $35.3M | 0.00% | −657,134−45.0% | Reduced |
| Price T Rowe Associates Inc | 685,876 | $30.1M | 0.00% | −110,138−13.8% | Reduced |
| Loomis Sayles & Co L P | 643,775 | $28.2M | 0.04% | +73,728+12.9% | Added |
| Frazier Life Sciences Management, L.P. | 603,521 | $26.5M | 2.26% | +603,521 | New |
| Great Point Partners LLC | 550,592 | $24.2M | 5.85% | +350,592+175.3% | Added |
| EcoR1 Capital, LLC | 547,453 | $24.0M | 0.75% | +547,453 | New |
| Victory Capital Management Inc | 551,415 | $23.5M | 0.02% | −17,153−3.0% | Reduced |
| Ikarian Capital, LLC | 478,784 | $21.0M | 6.39% | −134,342−21.9% | Reduced |
| Samlyn Capital, LLC | 426,543 | $18.7M | 0.28% | +117,428+38.0% | Added |
| Driehaus Capital Management LLC | 229,290 | $10.1M | 0.12% | −37,742−14.1% | Reduced |
| BlackRock Inc. | 190,129 | $8.34M | 0.00% | −13,866−6.8% | Reduced |
| Two Sigma Investments, LP | 177,322 | $7.78M | 0.02% | +25,961+17.2% | Added |
| Opaleye Management Inc. | 175,000 | $7.68M | 2.38% | +175,000 | New |
| Sofinnova Investments, Inc. | 163,559 | $7.18M | 0.60% | +163,559 | New |
| Millennium Management LLC | 163,367 | $7.17M | 0.01% | +10,635+7.0% | Added |
| Goldman Sachs Group Inc | 163,265 | $7.16M | 0.00% | +142,578+689.2% | Added |
| AXA S.A. | 145,254 | $6.37M | 0.02% | +20.0% | Added |
| Verition Fund Management LLC | 134,204 | $5.89M | 0.11% | −30,511−18.5% | Reduced |
| Handelsbanken Fonder AB | 130,000 | $5.70M | 0.03% | +50,000+62.5% | Added |
| Two Sigma Advisers, LP | 128,800 | $5.65M | 0.02% | +31,600+32.5% | Added |
| Dorsey Wright & Associates | 126,982 | $5.57M | 1.29% | −3,744−2.9% | Reduced |
| Altium Capital Management LP | 120,000 | $5.27M | 1.84% | −52,000−30.2% | Reduced |
| Ghost Tree Capital, LLC | 100,000 | $4.39M | 2.17% | +100,000 | New |
| Morgan Stanley | 87,917 | $3.86M | 0.00% | −62,095−41.4% | Reduced |
| Renaissance Technologies LLC | 64,399 | $2.83M | 0.00% | −8,780−12.0% | Reduced |
| Parkman Healthcare Partners LLC | 57,295 | $2.51M | 0.74% | −7,505−11.6% | Reduced |
| DAFNA Capital Management LLC | 53,200 | $2.33M | 0.61% | +53,200 | New |
| Sio Capital Management, LLC | 52,788 | $2.32M | 0.93% | −1,212−2.2% | Reduced |
| Boothbay Fund Management, LLC | 46,770 | $2.05M | 0.07% | −16,646−26.2% | Reduced |
| LMR Partners LLP | 40,283 | $1.77M | 0.03% | +283+0.7% | Added |
| Fred Alger Management, LLC | 39,246 | $1.72M | 0.01% | +39,246 | New |
| Caption Management, LLC | 38,013 | $1.67M | 0.11% | +38,013 | New |
| Bellevue Group AG | 36,500 | $1.60M | 0.02% | −17,200−32.0% | Reduced |
| Envestnet Asset Management Inc | 36,164 | $1.59M | 0.00% | −5,128−12.4% | Reduced |
| Acadian Asset Management LLC | 35,959 | $1.58M | 0.01% | −142,580−79.9% | Reduced |
| Stifel Financial Corp | 31,746 | $1.39M | 0.00% | −3,213−9.2% | Reduced |
| SG Americas Securities, LLC | 30,379 | $1.33M | 0.01% | +30,379 | New |
| TD Asset Management Inc | 29,086 | $1.28M | 0.00% | −2,500−7.9% | Reduced |
| Harbor Capital Advisors, Inc. | 28,942 | $1.27M | 0.60% | −5,658−16.4% | Reduced |
| Jump Financial, LLC | 28,176 | $1.24M | 0.05% | −3,031−9.7% | Reduced |
| Vident Investment Advisory, LLC | 21,572 | $947.0K | 0.02% | +3,639+20.3% | Added |
| Manufacturers Life Insurance Company, The | 19,533 | $830.9K | 0.00% | +19,533 | New |
| HighVista Strategies LLC | 18,298 | $803.0K | 0.51% | +18,298 | New |
| Ensign Peak Advisors, Inc | 18,260 | $801.0K | 0.00% | 00.0% | Unchanged |
| Woodline Partners LP | 17,954 | $788.0K | 0.01% | +17,954 | New |
| AtonRa Partners | 16,625 | $730.0K | 0.40% | +16,625 | New |
| Cinctive Capital Management LP | 15,000 | $658.0K | 0.03% | +15,000 | New |
| Pentwater Capital Management LP | 14,000 | $614.0K | 0.01% | −25,500−64.6% | Reduced |
| Erste Asset Management GmbH | 14,000 | $595.6K | 0.01% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 13,200 | $562.0K | 0.00% | +1,200+10.0% | Added |
| Squarepoint Ops LLC | 11,700 | $513.0K | 0.00% | +3,500+42.7% | Added |
| Legal & General Group Plc | 11,266 | $495.0K | 0.00% | +1,206+12.0% | Added |
| Geode Capital Management, LLC | 11,133 | $488.0K | 0.00% | +1,253+12.7% | Added |
| State Street Corp | 10,687 | $469.0K | 0.00% | +2,333+27.9% | Added |
| Marshall Wace, LLP | 10,619 | $466.0K | 0.00% | −39,779−78.9% | Reduced |
| Woodstock Corp | 10,320 | $453.0K | 0.05% | −362−3.4% | Reduced |
| Tekla Capital Management LLC | 10,086 | $443.0K | 0.02% | +10,086 | New |
| Vestmark Advisory Solutions, Inc. | 9,906 | $435.0K | 0.02% | +157+1.6% | Added |
| JPMorgan Chase & Co | 9,903 | $434.0K | 0.00% | +7,075+250.2% | Added |
| UBS Group AG | 8,884 | $389.0K | 0.00% | +7,992+896.0% | Added |
| Wrapmanager Inc | 8,835 | $388.0K | 0.10% | −231−2.5% | Reduced |
| Qube Research & Technologies Ltd | 8,806 | $386.0K | 0.00% | +8,806 | New |
| Jane Street Group, LLC | 7,991 | $351.0K | 0.00% | −5,395−40.3% | Reduced |
| Schonfeld Strategic Advisors LLC | 8,000 | $351.0K | 0.00% | +8,000 | New |
| Engineers Gate Manager LP | 7,770 | $341.0K | 0.01% | +7,770 | New |
| Personal Cfo Solutions, LLC | 7,455 | $327.0K | 0.06% | −12−0.2% | Reduced |
| Twelve Points Wealth Management LLC | 7,100 | $312.0K | 0.23% | 00.0% | Unchanged |
| TownSquare Capital, LLC | 7,088 | $311.0K | 0.01% | −94−1.3% | Reduced |
| Truist Financial Corp | 6,436 | $282.0K | 0.00% | −469−6.8% | Reduced |
| Shilanski & Associates, Inc. | 5,502 | $241.0K | 0.10% | +346+6.7% | Added |
| Claro Advisors LLC | 3,637 | $221.0K | 0.08% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 4,235 | $186.0K | 0.12% | −90−2.1% | Reduced |
| Advisor Group Holdings, Inc. | 4,039 | $176.0K | 0.00% | −295−6.8% | Reduced |
| Bank of America Corp | 3,110 | $136.0K | 0.00% | +586+23.2% | Added |
| Virtus ETF Advisers LLC | 2,987 | $131.0K | 0.06% | −179−5.7% | Reduced |
| Cutler Group LP | 2,550 | $111.0K | 0.01% | +1,300+104.0% | Added |
| Barclays PLC | 2,129 | $93.0K | 0.00% | −1,471−40.9% | Reduced |
| Prospera Financial Services Inc | 1,999 | $88.0K | 0.00% | +1,999 | New |
| Citigroup Inc | 748 | $33.0K | 0.00% | −54−6.7% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 535 | $23.0K | 0.00% | +535 | New |
| High Net Worth Advisory Group LLC | 500 | $22.0K | 0.01% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 396 | $17.0K | 0.00% | −3,331−89.4% | Reduced |
| Captrust Financial Advisors | 354 | $16.0K | 0.00% | −1,906−84.3% | Reduced |
| Leonteq Securities AG | 270 | $11.8K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 247 | $11.0K | 0.00% | +96+63.6% | Added |
| US Bancorp | 234 | $10.0K | 0.00% | −137−36.9% | Reduced |
| CIBC Private Wealth Group, LLC | 183 | $8.00K | 0.00% | +183 | New |
| Rockefeller Capital Management L.P. | 165 | $7.00K | 0.00% | 00.0% | Unchanged |
| American Portfolios Advisors | 96 | $4.21K | 0.00% | −18−15.8% | Reduced |
| Daiwa Securities Group Inc. | 58 | $3.00K | 0.00% | 00.0% | Unchanged |
| Zullo Investment Group, Inc. | 50 | $2.00K | 0.00% | 00.0% | Unchanged |