Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Bicycle Therapeutics PLC as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 97
- −7 vs. Q3 2024
- Shares held
- 41.9M
- +1.47M (+3.6%) vs. Q3 2024
- Total value
- $586.5M
- −$328.3M (−35.9%) vs. Q3 2024
- New holders
- 16
- 29 more added
- Sold out
- 23
- 36 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 10,885,357 | $152.4M | 1.63% | +1,485,397+15.8% | Added |
| Point72 Asset Management, L.P. | 4,554,900 | $63.8M | 0.17% | +3,655,101+406.2% | Added |
| FCPM III Services B.V. | 3,452,330 | $48.3M | 8.16% | +1,112,369+47.5% | Added |
| Westfield Capital Management Co LP | 2,610,337 | $36.5M | 0.16% | +759,392+41.0% | Added |
| Armistice Capital, LLC | 2,196,000 | $30.7M | 0.71% | +240,000+12.3% | Added |
| Siren, L.L.C. | 1,839,398 | $25.8M | 1.14% | +1,839,398 | New |
| Price T Rowe Associates Inc | 1,585,127 | $22.2M | 0.00% | −136,913−8.0% | Reduced |
| Deep Track Capital, LP | 1,276,081 | $17.9M | 0.67% | −2,271,920−64.0% | Reduced |
| Tybourne Capital Management (HK) Ltd | 1,269,535 | $17.8M | 4.46% | −125,000−9.0% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,155,651 | $16.2M | 0.04% | +395,764+52.1% | Added |
| Ra Capital Management, L.P. | 1,093,477 | $15.3M | 0.20% | −1,159,523−51.5% | Reduced |
| Candriam Luxembourg S.C.A. | 1,087,876 | $15.2M | 0.09% | +37,278+3.5% | Added |
| EcoR1 Capital, LLC | 910,000 | $12.7M | 0.51% | 00.0% | Unchanged |
| Morgan Stanley | 862,137 | $12.1M | 0.00% | −487,757−36.1% | Reduced |
| AXA S.A. | 553,959 | $7.76M | 0.02% | −440−0.1% | Reduced |
| Long Focus Capital Management, LLC | 543,092 | $7.60M | 0.58% | +543,092 | New |
| Principal Financial Group Inc | 406,470 | $5.69M | 0.00% | −36,671−8.3% | Reduced |
| Bank of America Corp | 392,859 | $5.50M | 0.00% | +7,994+2.1% | Added |
| BlackRock, Inc. | 365,408 | $5.12M | 0.00% | −54,355−12.9% | Reduced |
| Parkman Healthcare Partners LLC | 352,481 | $4.93M | 0.66% | −92,915−20.9% | Reduced |
| Platinum Investment Management Ltd | 309,059 | $4.33M | 0.25% | +36,910+13.6% | Added |
| Verition Fund Management LLC | 280,327 | $3.92M | 0.02% | +68,176+32.1% | Added |
| Renaissance Technologies LLC | 269,500 | $3.77M | 0.01% | −3,100−1.1% | Reduced |
| Palo Alto Investors LP | 248,934 | $3.49M | 0.54% | +189,352+317.8% | Added |
| Pinnacle Associates Ltd | 226,742 | $3.17M | 0.04% | +226,742 | New |
| Aquilo Capital Management, LLC | 221,911 | $3.11M | 5.32% | +40,000+22.0% | Added |
| TD Asset Management Inc | 216,016 | $3.02M | 0.00% | −5,400−2.4% | Reduced |
| Handelsbanken Fonder AB | 215,900 | $3.02M | 0.01% | −2,800−1.3% | Reduced |
| Perceptive Advisors LLC | 197,108 | $2.76M | 0.08% | −58,886−23.0% | Reduced |
| Millennium Management LLC | 176,757 | $2.47M | 0.00% | +176,757 | New |
| Caption Management, LLC | 163,076 | $2.28M | 0.09% | +163,076 | New |
| Citadel Advisors LLC | 144,230 | $2.02M | 0.00% | +41,481+40.4% | Added |
| Legal & General Group Plc | 139,075 | $1.95M | 0.00% | −99,741−41.8% | Reduced |
| Silvercrest Asset Management Group LLC | 137,740 | $1.93M | 0.01% | −1,353−1.0% | Reduced |
| UBS Group AG | 132,361 | $1.85M | 0.00% | +120,295+997.0% | Added |
| Harbor Capital Advisors, Inc. | 131,505 | $1.84M | 0.08% | −2,202−1.6% | Reduced |
| Manufacturers Life Insurance Company, The | 124,497 | $1.74M | 0.00% | −5,208−4.0% | Reduced |
| HighVista Strategies LLC | 124,430 | $1.74M | 0.65% | −15,114−10.8% | Reduced |
| DAFNA Capital Management LLC | 120,799 | $1.69M | 0.43% | −1,401−1.1% | Reduced |
| Springhill Fund Asset Management (HK) Co Ltd | 116,400 | $1.63M | 2.65% | +116,400 | New |
| State Street Corp | 87,765 | $1.23M | 0.00% | +1,494+1.7% | Added |
| UBS Oconnor LLC | 80,236 | $1.12M | 0.03% | +44,260+123.0% | Added |
| Nan Fung Group Holdings Ltd | 68,943 | $965.2K | 0.83% | +37,358+118.3% | Added |
| Cubist Systematic Strategies, LLC | 49,899 | $698.6K | 0.01% | −28,721−36.5% | Reduced |
| Voya Investment Management LLC | 48,420 | $677.9K | 0.00% | −56,870−54.0% | Reduced |
| EntryPoint Capital, LLC | 43,873 | $614.2K | 0.26% | +43,873 | New |
| Skandinaviska Enskilda Banken AB (publ) | 42,729 | $603.3K | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 42,500 | $595.0K | 0.00% | −380,500−90.0% | Reduced |
| Altium Capital Management LP | 40,352 | $564.9K | 0.18% | −44,648−52.5% | Reduced |
| Geode Capital Management, LLC | 38,815 | $543.4K | 0.00% | +480+1.3% | Added |
| DekaBank Deutsche Girozentrale | 30,000 | $414.0K | 0.00% | 00.0% | Unchanged |
| Woodstock Corp | 24,981 | $349.7K | 0.03% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 24,600 | $344.4K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 23,991 | $335.9K | 0.00% | +3,811+18.9% | Added |
| Wexford Capital LP | 17,879 | $250.3K | 0.06% | −17,000−48.7% | Reduced |
| Tocqueville Asset Management L.P. | 14,700 | $205.8K | 0.00% | −700−4.5% | Reduced |
| Erste Asset Management GmbH | 14,000 | $203.7K | 0.00% | 00.0% | Unchanged |
| Horizon Kinetics Asset Management LLC | 14,396 | $201.5K | 0.00% | +604+4.4% | Added |
| The PNC Financial Services Group, Inc. | 12,900 | $180.6K | 0.00% | 00.0% | Unchanged |
| Crossmark Global Holdings, Inc. | 11,378 | $159.0K | 0.00% | +11+0.1% | Added |
| Royal Bank of Canada | 9,773 | $137.0K | 0.00% | +9,310+2,010.8% | Added |
| China Universal Asset Management Co., Ltd. | 9,329 | $130.6K | 0.01% | +2,191+30.7% | Added |
| JPMorgan Chase & Co | 7,707 | $107.9K | 0.00% | −717−8.5% | Reduced |
| Exchange Traded Concepts, LLC | 6,707 | $93.9K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 6,417 | $89.8K | 0.00% | −1,653−20.5% | Reduced |
| HighMark Wealth Management LLC | 4,435 | $62.1K | 0.04% | 00.0% | Unchanged |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 4,043 | $56.6K | 0.00% | +4,043 | New |
| Virtus ETF Advisers LLC | 3,535 | $49.5K | 0.02% | −254−6.7% | Reduced |
| Barclays PLC | 2,612 | $36.6K | 0.00% | +2,345+878.3% | Added |
| Natixis | 2,298 | $33.2K | 0.00% | −437−16.0% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 1,466 | $21.3K | 0.00% | +124+9.2% | Added |
| Assetmark, Inc | 1,260 | $17.6K | 0.00% | −259−17.1% | Reduced |
| Rhumbline Advisers | 1,157 | $16.2K | 0.00% | +57+5.2% | Added |
| Coppell Advisory Solutions LLC | 1,076 | $15.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 925 | $12.9K | 0.00% | +296+47.1% | Added |
| GF Fund Management Co. Ltd. | 924 | $12.9K | 0.00% | +924 | New |
| GAMMA Investing LLC | 917 | $12.8K | 0.00% | −1,109−54.7% | Reduced |
| Advisor Group Holdings, Inc. | 760 | $10.6K | 0.00% | −282−27.1% | Reduced |
| BNP Paribas Arbitrage, SA | 680 | $9.52K | 0.00% | −118−14.8% | Reduced |
| Citigroup Inc | 630 | $8.82K | 0.00% | −38−5.7% | Reduced |
| Manchester Capital Management LLC | 590 | $8.26K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 466 | $6.52K | 0.00% | +466 | New |
| FMR LLC | 316 | $4.42K | 0.00% | −150,200−99.8% | Reduced |
| R Squared Ltd | 180 | $2.52K | 0.00% | +180 | New |
| Winch Advisory Services, LLC | 172 | $2.41K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 150 | $2.10K | 0.00% | +50+50.0% | Added |
| Caitong International Asset Management Co., Ltd | 148 | $2.07K | 0.00% | +148 | New |
| AdvisorNet Financial, Inc | 100 | $1.40K | 0.00% | +100 | New |
| TD Waterhouse Canada Inc. | 100 | $1.40K | 0.00% | +100 | New |
| Daiwa Securities Group Inc. | 103 | $1.00K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 61 | $854 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 24 | $336 | 0.00% | +4+20.0% | Added |
| Bell Investment Advisors, Inc | 22 | $308 | 0.00% | 00.0% | Unchanged |
| Caitlin John, LLC | 14 | $196 | 0.00% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 11 | $154 | 0.00% | −524−97.9% | Reduced |
| Steward Partners Investment Advisory, LLC | 10 | $140 | 0.00% | +10 | New |
| SBI Securities Co., Ltd. | 7 | $98 | 0.00% | +7 | New |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −1,002,780−100.0% | Sold out |
| First Light Asset Management, LLC | 0 | $0 | 0.00% | −967,006−100.0% | Sold out |
| Camber Capital Management LP | 0 | $0 | 0.00% | −915,000−100.0% | Sold out |