Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Bicycle Therapeutics PLC as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 101
- +33 vs. Q3 2021
- Shares held
- 21.6M
- +7.37M (+51.9%) vs. Q3 2021
- Total value
- $1.31B
- +$721.6M (+122.2%) vs. Q3 2021
- New holders
- 45
- 26 more added
- Sold out
- 12
- 25 more reduced
1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ridgeback Capital Investments L.P. | 2,164,801 | $131.8M | 71.77% | +2,164,801 | New |
| Tybourne Capital Management (HK) Ltd | 2,053,804 | $125.0M | 3.71% | +95,843+4.9% | Added |
| Janus Henderson Group PLC | 1,695,409 | $103.2M | 0.04% | −47,596−2.7% | Reduced |
| Point72 Asset Management, L.P. | 1,572,823 | $95.7M | 0.42% | −42,269−2.6% | Reduced |
| FMR LLC | 1,460,882 | $88.9M | 0.01% | +999,253+216.5% | Added |
| Eventide Asset Management, LLC | 1,263,471 | $76.9M | 0.98% | +100,000+8.6% | Added |
| Deep Track Capital, LP | 1,100,000 | $67.0M | 4.95% | +1,100,000 | New |
| First Light Asset Management, LLC | 1,000,783 | $60.9M | 4.36% | +268,052+36.6% | Added |
| SV Health Investors, LLC | 918,154 | $55.9M | 36.13% | −518,302−36.1% | Reduced |
| Logos Global Management LP | 870,000 | $53.0M | 5.46% | −605,000−41.0% | Reduced |
| RTW Investments, LP | 869,271 | $52.9M | 0.77% | +869,271 | New |
| Price T Rowe Associates Inc | 796,014 | $48.5M | 0.00% | +796,014 | New |
| Ikarian Capital, LLC | 613,126 | $37.3M | 10.68% | +86,626+16.5% | Added |
| Loomis Sayles & Co L P | 570,047 | $34.7M | 0.04% | +570,047 | New |
| Victory Capital Management Inc | 568,568 | $34.6M | 0.03% | +414,845+269.9% | Added |
| Frazier Management LLC | 555,240 | $33.8M | 2.60% | +112,360+25.4% | Added |
| Samlyn Capital, LLC | 309,115 | $18.8M | 0.29% | −145,766−32.0% | Reduced |
| Driehaus Capital Management LLC | 267,032 | $16.3M | 0.17% | +267,032 | New |
| BlackRock Inc. | 203,995 | $12.4M | 0.00% | +203,995 | New |
| Great Point Partners LLC | 200,000 | $12.2M | 2.72% | +200,000 | New |
| Acadian Asset Management LLC | 178,539 | $10.9M | 0.04% | +157,365+743.2% | Added |
| Altium Capital Management LP | 172,000 | $10.5M | 2.94% | +80,000+87.0% | Added |
| Verition Fund Management LLC | 164,715 | $10.0M | 0.13% | −14,546−8.1% | Reduced |
| Millennium Management LLC | 152,732 | $9.30M | 0.01% | +152,732 | New |
| Two Sigma Investments, LP | 151,361 | $9.21M | 0.02% | +59,169+64.2% | Added |
| Morgan Stanley | 150,012 | $9.13M | 0.00% | +5,399+3.7% | Added |
| AXA S.A. | 145,252 | $8.84M | 0.02% | −53,421−26.9% | Reduced |
| Dorsey Wright & Associates | 130,726 | $7.96M | 1.64% | +2,938+2.3% | Added |
| Two Sigma Advisers, LP | 97,200 | $5.92M | 0.01% | +50,500+108.1% | Added |
| Handelsbanken Fonder AB | 80,000 | $4.87M | 0.02% | +80,000 | New |
| Renaissance Technologies LLC | 73,179 | $4.45M | 0.01% | +73,179 | New |
| Parkman Healthcare Partners LLC | 64,800 | $3.94M | 0.89% | −4,749−6.8% | Reduced |
| Boothbay Fund Management, LLC | 63,416 | $3.86M | 0.13% | +8,510+15.5% | Added |
| Citadel Advisors LLC | 58,187 | $3.54M | 0.00% | +32,840+129.6% | Added |
| Sio Capital Management, LLC | 54,000 | $3.29M | 1.00% | +54,000 | New |
| Bellevue Group AG | 53,700 | $3.27M | 0.03% | −12,000−18.3% | Reduced |
| Voloridge Investment Management, LLC | 52,575 | $3.20M | 0.02% | +52,575 | New |
| Marshall Wace, LLP | 50,398 | $3.07M | 0.01% | +42,704+555.0% | Added |
| Goldstream Capital Management Ltd | 48,257 | $2.94M | 0.72% | +48,257 | New |
| Envestnet Asset Management Inc | 41,292 | $2.51M | 0.00% | −2,004−4.6% | Reduced |
| LMR Partners LLP | 40,000 | $2.44M | 0.03% | +40,000 | New |
| Pentwater Capital Management LP | 39,500 | $2.40M | 0.04% | +27,500+229.2% | Added |
| Stifel Financial Corp | 34,959 | $2.13M | 0.00% | −2,928−7.7% | Reduced |
| Harbor Capital Advisors, Inc. | 34,600 | $2.11M | 0.77% | +34,600 | New |
| TD Asset Management Inc | 31,586 | $1.92M | 0.00% | +31,586 | New |
| Laurion Capital Management LP | 31,410 | $1.91M | 0.03% | −3,734−10.6% | Reduced |
| Jump Financial, LLC | 31,207 | $1.90M | 0.12% | +14,007+81.4% | Added |
| Goldman Sachs Group Inc | 20,687 | $1.26M | 0.00% | +5,824+39.2% | Added |
| Ensign Peak Advisors, Inc | 18,260 | $1.11M | 0.00% | +18,260 | New |
| Vident Investment Advisory, LLC | 17,933 | $1.09M | 0.03% | +17,933 | New |
| Erste Asset Management GmbH | 14,000 | $821.5K | 0.01% | +14,000 | New |
| Jane Street Group, LLC | 13,386 | $814.0K | 0.00% | +13,386 | New |
| DekaBank Deutsche Girozentrale | 12,000 | $675.0K | 0.00% | +12,000 | New |
| Woodstock Corp | 10,682 | $650.0K | 0.07% | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 10,250 | $624.0K | 0.08% | +10,250 | New |
| Legal & General Group Plc | 10,060 | $612.0K | 0.00% | −148−1.4% | Reduced |
| Geode Capital Management, LLC | 9,880 | $601.0K | 0.00% | 00.0% | Unchanged |
| Vestmark Advisory Solutions, Inc. | 9,749 | $593.0K | 0.03% | −128−1.3% | Reduced |
| Wrapmanager Inc | 9,066 | $552.0K | 0.14% | −554−5.8% | Reduced |
| State Street Corp | 8,354 | $509.0K | 0.00% | +1,654+24.7% | Added |
| Squarepoint Ops LLC | 8,200 | $499.0K | 0.00% | +8,200 | New |
| Personal Cfo Solutions, LLC | 7,467 | $455.0K | 0.09% | −91−1.2% | Reduced |
| TownSquare Capital, LLC | 7,182 | $437.0K | 0.01% | −605−7.8% | Reduced |
| Twelve Points Wealth Management LLC | 7,100 | $432.0K | 0.35% | +7,100 | New |
| Truist Financial Corp | 6,905 | $420.0K | 0.00% | −476−6.4% | Reduced |
| Wells Fargo & Company | 6,001 | $365.0K | 0.00% | −103−1.7% | Reduced |
| Shilanski & Associates, Inc. | 5,156 | $314.0K | 0.13% | +5,156 | New |
| Trexquant Investment LP | 4,370 | $266.0K | 0.02% | +4,370 | New |
| Advisor Group Holdings, Inc. | 4,334 | $264.0K | 0.00% | −730−14.4% | Reduced |
| HighMark Wealth Management LLC | 4,325 | $263.0K | 0.17% | +3,699+590.9% | Added |
| Castleview Partners, LLC | 15,704 | $258.0K | 0.00% | +15,704 | New |
| Susquehanna Fundamental Investments, LLC | 4,200 | $256.0K | 0.01% | +4,200 | New |
| SEI Investments Co | 3,760 | $229.0K | 0.00% | +3,760 | New |
| Tower Research Capital LLC (TRC) | 3,727 | $227.0K | 0.00% | +3,727 | New |
| Claro Advisors LLC | 3,637 | $221.0K | 0.08% | +3,637 | New |
| Barclays PLC | 3,600 | $219.0K | 0.00% | −2,522−41.2% | Reduced |
| Difesa Capital Management, LP | 3,500 | $213.0K | 0.15% | +3,500 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 3,373 | $205.0K | 0.00% | +3,373 | New |
| Virtus ETF Advisers LLC | 3,166 | $193.0K | 0.07% | −3,964−55.6% | Reduced |
| Northern Trust Corp | 2,905 | $177.0K | 0.00% | +2,905 | New |
| JPMorgan Chase & Co | 2,828 | $172.0K | 0.00% | +1,463+107.2% | Added |
| Bank of America Corp | 2,524 | $153.0K | 0.00% | +368+17.1% | Added |
| Captrust Financial Advisors | 2,260 | $138.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 1,557 | $94.0K | 0.00% | +1,557 | New |
| Cutler Group LP | 1,250 | $76.0K | 0.01% | −13,376−91.5% | Reduced |
| UBS Group AG | 892 | $54.0K | 0.00% | +46+5.4% | Added |
| Citigroup Inc | 802 | $49.0K | 0.00% | +649+424.2% | Added |
| Signet Financial Management, LLC | 665 | $40.0K | 0.01% | +665 | New |
| Quantbot Technologies LP | 559 | $34.0K | 0.00% | +559 | New |
| High Net Worth Advisory Group LLC | 500 | $30.0K | 0.01% | +500 | New |
| US Bancorp | 371 | $23.0K | 0.00% | −9,618−96.3% | Reduced |
| Leonteq Securities AG | 270 | $16.4K | 0.00% | +270 | New |
| Rockefeller Capital Management L.P. | 165 | $10.0K | 0.00% | −181−52.3% | Reduced |
| Royal Bank of Canada | 151 | $9.00K | 0.00% | +47+45.2% | Added |
| American Portfolios Advisors | 114 | $6.94K | 0.00% | 00.0% | Unchanged |
| McDonald Partners LLC | 70 | $4.26K | 0.00% | +70 | New |
| Absolute Capital Management, LLC | 70 | $4.26K | 0.00% | +70 | New |
| Daiwa Securities Group Inc. | 58 | $4.00K | 0.00% | +58 | New |
| Zullo Investment Group, Inc. | 50 | $3.00K | 0.00% | +50 | New |
| Newbridge Financial Services Group, Inc. | 40 | $2.00K | 0.00% | 00.0% | Unchanged |