Bicycle Therapeutics PLC

BCYC

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001761612

SEC filings (opens in a new tab)

No open-market purchases or sales by Bicycle Therapeutics PLC insiders were filed in the last 90 days; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

Q4 2021 vs. Q3 2021

How the institutions holding Bicycle Therapeutics PLC changed between Q3 2021 and Q4 2021.

All holders in Q4 2021 All holders in Q3 2021

13F holders of BCYC: Q3 2021 compared with Q4 2021
Measure	Q3 2021	Of which not filed for Q4 2021	Q4 2021	Change
Holders	69	1	101	+33
Shares	14.2M	17.5K	21.6M	+7.37M (+51.9%)
Value	$591.1M	$726.0K	$1.31B	+$721.6M (+122.2%)

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so the changes leave them out.

New holders (45)

Institutions that held Bicycle Therapeutics PLC at the end of Q4 2021 but not at the end of Q3 2021.

Institutions new to BCYC in Q4 2021
Institution	Shares	Value	% of portfolio
Ridgeback Capital Investments L.P.	2,164,801	$131.8M	71.77%
Deep Track Capital, LP	1,100,000	$67.0M	4.95%
RTW Investments, LP	869,271	$52.9M	0.77%
Price T Rowe Associates Inc	796,014	$48.5M	0.00%
Loomis Sayles & Co L P	570,047	$34.7M	0.04%
Driehaus Capital Management LLC	267,032	$16.3M	0.17%
BlackRock Inc.	203,995	$12.4M	0.00%
Great Point Partners LLC	200,000	$12.2M	2.72%
Millennium Management LLC	152,732	$9.30M	0.01%
Handelsbanken Fonder AB	80,000	$4.87M	0.02%
Renaissance Technologies LLC	73,179	$4.45M	0.01%
Sio Capital Management, LLC	54,000	$3.29M	1.00%
Voloridge Investment Management, LLC	52,575	$3.20M	0.02%
Goldstream Capital Management Ltd	48,257	$2.94M	0.72%
LMR Partners LLP	40,000	$2.44M	0.03%
Harbor Capital Advisors, Inc.	34,600	$2.11M	0.77%
TD Asset Management Inc	31,586	$1.92M	0.00%
Ensign Peak Advisors, Inc	18,260	$1.11M	0.00%
Vident Investment Advisory, LLC	17,933	$1.09M	0.03%
Erste Asset Management GmbH	14,000	$821.5K	0.01%
Jane Street Group, LLC	13,386	$814.0K	0.00%
DekaBank Deutsche Girozentrale	12,000	$675.0K	0.00%
Soleus Capital Management, L.P.	10,250	$624.0K	0.08%
Squarepoint Ops LLC	8,200	$499.0K	0.00%
Twelve Points Wealth Management LLC	7,100	$432.0K	0.35%
Shilanski & Associates, Inc.	5,156	$314.0K	0.13%
Trexquant Investment LP	4,370	$266.0K	0.02%
Castleview Partners, LLC	15,704	$258.0K	0.00%
Susquehanna Fundamental Investments, LLC	4,200	$256.0K	0.01%
SEI Investments Co	3,760	$229.0K	0.00%
Tower Research Capital LLC (TRC)	3,727	$227.0K	0.00%
Claro Advisors LLC	3,637	$221.0K	0.08%
Difesa Capital Management, LP	3,500	$213.0K	0.15%
Commonwealth of Pennsylvania Public School Empls Retrmt Sys	3,373	$205.0K	0.00%
Northern Trust Corp	2,905	$177.0K	0.00%
Simplex Trading, LLC	1,557	$94.0K	0.00%
Signet Financial Management, LLC	665	$40.0K	0.01%
Quantbot Technologies LP	559	$34.0K	0.00%
High Net Worth Advisory Group LLC	500	$30.0K	0.01%
Leonteq Securities AG	270	$16.4K	0.00%
McDonald Partners LLC	70	$4.26K	0.00%
Absolute Capital Management, LLC	70	$4.26K	0.00%
Daiwa Securities Group Inc.	58	$4.00K	0.00%
Zullo Investment Group, Inc.	50	$3.00K	0.00%
Parallel Advisors, LLC	5	$0	0.00%

Sold out (12)

Institutions that held Bicycle Therapeutics PLC at the end of Q3 2021 and filed for Q4 2021 without it.

Institutions that sold out of BCYC in Q4 2021
Institution	Shares, Q3 2021	Value, Q3 2021
Atlas Venture Advisors, Inc.	307,696	$12.8M
Ghost Tree Capital, LLC	100,000	$4.16M
Schonfeld Strategic Advisors LLC	59,972	$2.49M
Moody Aldrich Partners LLC	59,053	$2.46M
Acuta Capital Partners, LLC	38,184	$1.59M
Susquehanna International Group, LLP	18,475	$768.0K
Bank of New York Mellon Corp	8,490	$353.0K
Glenmede Trust Co NA	6,436	$267.0K
State of New Jersey Common Pension Fund D	4,880	$203.0K
KBC Group NV	3,750	$156.0K
Evolution Wealth Advisors, LLC	120	$5.00K
Deutsche Bank AG	1	$0

Not filed for Q4 2021 yet (1)

Institutions that held Bicycle Therapeutics PLC at the end of Q3 2021 and haven't filed a 13F for Q4 2021. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding BCYC in Q3 2021 that haven't filed for Q4 2021
Institution	Shares, Q3 2021	Value, Q3 2021
Marshall Wace North America L.P.	17,458	$726.0K