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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Bicycle Therapeutics PLC as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
+16 vs. Q2 2021
Shares held
14.2M
+1.80M (+14.5%) vs. Q2 2021
Total value
$591.1M
+$214.2M (+56.8%) vs. Q2 2021
New holders
22
14 more added
Sold out
6
24 more reduced

1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 69 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ3 2021: $591.1M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q2 2021.

Institutions holding BCYC in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Tybourne Capital Management (HK) Ltd1,957,961$81.4M2.05%00.0%Unchanged
Janus Henderson Group PLC1,743,005$72.6M0.03%−106,715−5.8%Reduced
Point72 Asset Management, L.P.1,615,092$67.2M0.32%−190,843−10.6%Reduced
Logos Global Management LP1,475,000$61.3M4.42%+760,000+106.3%Added
SV Health Investors, LLC1,436,456$59.7M29.23%−478,818−25.0%Reduced
Eventide Asset Management, LLC1,163,471$48.4M0.64%00.0%Unchanged
First Light Asset Management, LLC732,731$30.5M2.01%+732,731New
Ikarian Capital, LLC526,500$21.9M5.01%+526,500New
FMR LLC461,629$19.2M0.00%+250,185+118.3%Added
Samlyn Capital, LLC454,881$18.9M0.28%+11,615+2.6%Added
Frazier Management LLC442,880$18.4M1.47%+442,880New
Atlas Venture Advisors, Inc.307,696$12.8M1.52%00.0%Unchanged
AXA S.A.198,673$8.26M0.02%+1,163+0.6%Added
Verition Fund Management LLC179,261$7.46M0.11%−32,613−15.4%Reduced
Victory Capital Management Inc153,723$6.39M0.01%−16,652−9.8%Reduced
Morgan Stanley144,613$6.01M0.00%+78,407+118.4%Added
Dorsey Wright & Associates127,788$5.32M1.17%+2,113+1.7%Added
Ghost Tree Capital, LLC100,000$4.16M1.37%−100,000−50.0%Reduced
Two Sigma Investments, LP92,192$3.83M0.01%+92,192New
Altium Capital Management LP92,000$3.83M1.02%+92,000New
Parkman Healthcare Partners LLC69,549$2.89M0.73%−11,290−14.0%Reduced
Bellevue Group AG65,700$2.73M0.03%+65,700New
Schonfeld Strategic Advisors LLC59,972$2.49M0.03%+5,110+9.3%Added
Moody Aldrich Partners LLC59,053$2.46M0.31%−14,055−19.2%Reduced
Boothbay Fund Management, LLC54,906$2.28M0.09%+54,906New
Two Sigma Advisers, LP46,700$1.94M0.01%+46,700New
Envestnet Asset Management Inc43,296$1.80M0.00%+631+1.5%Added
Acuta Capital Partners, LLC38,184$1.59M0.57%+38,184New
Stifel Financial Corp37,887$1.58M0.00%−4,251−10.1%Reduced
Laurion Capital Management LP35,144$1.46M0.02%−14,648−29.4%Reduced
Citadel Advisors LLC25,347$1.05M0.00%+25,347New
Acadian Asset Management LLC21,174$878.0K0.00%+12,221+136.5%Added
Susquehanna International Group, LLP18,475$768.0K0.00%+18,475New
Marshall Wace North America L.P.17,458$726.0K0.00%+17,458New
Jump Financial, LLC17,200$715.0K0.05%+17,200New
Goldman Sachs Group Inc14,863$618.0K0.00%+14,863New
Cutler Group LP14,626$608.0K0.05%+14,626New
Pentwater Capital Management LP12,000$499.0K0.01%00.0%Unchanged
Woodstock Corp10,682$444.0K0.05%+10,682New
Legal & General Group Plc10,208$423.0K0.00%+2,177+27.1%Added
US Bancorp9,989$416.0K0.00%−2,752−21.6%Reduced
Vestmark Advisory Solutions, Inc.9,877$411.0K0.03%−178−1.8%Reduced
Geode Capital Management, LLC9,880$410.0K0.00%+2,401+32.1%Added
Wrapmanager Inc9,620$400.0K0.10%−46−0.5%Reduced
Bank of New York Mellon Corp8,490$353.0K0.00%−3,630−30.0%Reduced
TownSquare Capital, LLC7,787$324.0K0.01%−41−0.5%Reduced
Marshall Wace, LLP7,694$320.0K0.00%00.0%Unchanged
Personal Cfo Solutions, LLC7,558$314.0K0.06%+273+3.7%Added
Truist Financial Corp7,381$307.0K0.00%+252+3.5%Added
Virtus ETF Advisers LLC7,130$297.0K0.13%−379−5.0%Reduced
State Street Corp6,700$279.0K0.00%+6,700New
Glenmede Trust Co NA6,436$267.0K0.00%−3,058−32.2%Reduced
Barclays PLC6,122$255.0K0.00%+1,522+33.1%Added
Wells Fargo & Company6,104$254.0K0.00%+6,104New
Advisor Group Holdings, Inc.5,064$210.0K0.00%−13,132−72.2%Reduced
State of New Jersey Common Pension Fund D4,880$203.0K0.00%+4,880New
KBC Group NV3,750$156.0K0.00%00.0%Unchanged
Captrust Financial Advisors2,260$94.0K0.00%−1,000−30.7%Reduced
Bank of America Corp2,156$90.0K0.00%−176−7.5%Reduced
JPMorgan Chase & Co1,365$57.0K0.00%−691−33.6%Reduced
UBS Group AG846$35.0K0.00%−869−50.7%Reduced
HighMark Wealth Management LLC626$26.0K0.02%+626New
Rockefeller Capital Management L.P.346$14.0K0.00%+346New
Citigroup Inc153$6.00K0.00%−913−85.6%Reduced
Evolution Wealth Advisors, LLC120$5.00K0.00%−277−69.8%Reduced
American Portfolios Advisors114$4.74K0.00%00.0%Unchanged
Royal Bank of Canada104$4.00K0.00%+104New
Newbridge Financial Services Group, Inc.40$2.00K0.00%00.0%Unchanged
Deutsche Bank AG1$00.00%00.0%Unchanged
FIL Ltd0$00.00%−525,623−100.0%Sold out
Millennium Management LLC0$00.00%−20,363−100.0%Sold out
Renaissance Technologies LLC0$00.00%−14,600−100.0%Sold out
WealthShield Partners, LLC0$00.00%−879−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−500−100.0%Sold out
Advisory Services Network, LLC0$00.00%−100−100.0%Sold out
Castleview Partners, LLC––––Not filed