Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Bicycle Therapeutics PLC as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 87
- +9 vs. Q3 2022
- Shares held
- 23.5M
- +1.29M (+5.8%) vs. Q3 2022
- Total value
- $695.9M
- +$179.0M (+34.6%) vs. Q3 2022
- New holders
- 17
- 17 more added
- Sold out
- 8
- 34 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Deep Track Capital, LP | 2,819,045 | $83.4M | 3.64% | −80,955−2.8% | Reduced |
| Ridgeback Capital Investments L.P. | 2,264,801 | $67.0M | 80.44% | +2,264,801 | New |
| Janus Henderson Group PLC | 1,503,447 | $44.5M | 0.03% | −177,402−10.6% | Reduced |
| Logos Global Management LP | 1,435,000 | $42.5M | 4.98% | −565,000−28.2% | Reduced |
| RTW Investments, LP | 1,258,587 | $37.3M | 0.76% | −17,689−1.4% | Reduced |
| Paradigm Biocapital Advisors LP | 1,233,280 | $36.5M | 4.29% | +74,594+6.4% | Added |
| Candriam Luxembourg S.C.A. | 1,175,211 | $34.8M | 0.23% | −57,043−4.6% | Reduced |
| Point72 Asset Management, L.P. | 1,007,978 | $29.8M | 0.11% | −247,440−19.7% | Reduced |
| Samlyn Capital, LLC | 987,888 | $29.2M | 0.57% | −306,197−23.7% | Reduced |
| Tybourne Capital Management (HK) Ltd | 905,722 | $26.8M | 2.67% | −135,609−13.0% | Reduced |
| Eventide Asset Management, LLC | 853,800 | $25.3M | 0.50% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 843,814 | $25.0M | 0.15% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 750,000 | $22.2M | 0.18% | +750,000 | New |
| Morgan Stanley | 721,559 | $21.4M | 0.00% | −138,292−16.1% | Reduced |
| First Light Asset Management, LLC | 696,432 | $20.6M | 1.91% | −8,289−1.2% | Reduced |
| Sio Capital Management, LLC | 683,425 | $20.2M | 10.78% | 00.0% | Unchanged |
| Verition Fund Management LLC | 380,849 | $11.3M | 0.22% | +32,336+9.3% | Added |
| AXA S.A. | 380,555 | $11.3M | 0.04% | −30,085−7.3% | Reduced |
| FMR LLC | 377,647 | $11.2M | 0.00% | −287,159−43.2% | Reduced |
| Price T Rowe Associates Inc | 338,733 | $10.0M | 0.00% | −78,607−18.8% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 300,968 | $8.91M | 0.03% | +300,968 | New |
| Soleus Capital Management, L.P. | 258,400 | $7.65M | 1.10% | +258,400 | New |
| Pura Vida Investments, LLC | 239,015 | $7.07M | 1.19% | +25,894+12.1% | Added |
| BlackRock Inc. | 189,818 | $5.62M | 0.00% | +8,771+4.8% | Added |
| Millennium Management LLC | 168,723 | $4.99M | 0.01% | +25,677+18.0% | Added |
| Two Sigma Advisers, LP | 161,800 | $4.79M | 0.01% | −100,900−38.4% | Reduced |
| Handelsbanken Fonder AB | 131,800 | $3.90M | 0.02% | +1,800+1.4% | Added |
| DAFNA Capital Management LLC | 122,200 | $3.62M | 1.02% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 104,866 | $3.10M | 0.05% | +26,184+33.3% | Added |
| HighVista Strategies LLC | 92,434 | $2.74M | 1.62% | −44,325−32.4% | Reduced |
| Parkman Healthcare Partners LLC | 91,332 | $2.70M | 0.72% | +9,968+12.3% | Added |
| Tekla Capital Management LLC | 88,676 | $2.62M | 0.10% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 83,206 | $2.46M | 0.00% | −42,483−33.8% | Reduced |
| Goldman Sachs Group Inc | 80,553 | $2.38M | 0.00% | −24,738−23.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 79,746 | $2.36M | 0.02% | +58,946+283.4% | Added |
| Alliancebernstein L.P. | 72,549 | $2.15M | 0.00% | +9,111+14.4% | Added |
| Bellevue Group AG | 70,200 | $2.08M | 0.03% | −27,900−28.4% | Reduced |
| Voya Investment Management LLC | 66,040 | $1.95M | 0.00% | −1,707−2.5% | Reduced |
| Group One Trading, L.P. | 38,784 | $1.15M | 0.04% | +38,784 | New |
| Susquehanna International Group, LLP | 37,055 | $1.10M | 0.00% | +37,055 | New |
| L & S Advisors Inc | 34,950 | $1.03M | 0.19% | −7,815−18.3% | Reduced |
| Citadel Advisors LLC | 32,990 | $976.5K | 0.00% | −15,414−31.8% | Reduced |
| Manufacturers Life Insurance Company, The | 25,136 | $743.0K | 0.00% | 00.0% | Unchanged |
| Harbor Capital Advisors, Inc. | 24,147 | $714.8K | 0.71% | −21,520−47.1% | Reduced |
| Vident Investment Advisory, LLC | 23,957 | $709.1K | 0.03% | +23,957 | New |
| TD Asset Management Inc | 23,586 | $698.1K | 0.00% | +8,000+51.3% | Added |
| Eagle Health Investments LP | 23,500 | $695.6K | 0.16% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 17,144 | $507.0K | 0.00% | −4,276−20.0% | Reduced |
| AtonRa Partners | 17,067 | $505.2K | 0.64% | −4,527−21.0% | Reduced |
| Allianz Asset Management GmbH | 15,200 | $449.9K | 0.00% | 00.0% | Unchanged |
| Woodstock Corp | 14,840 | $439.3K | 0.06% | 00.0% | Unchanged |
| Simplex Trading, LLC | 14,334 | $424.0K | 0.02% | +14,092+5,823.1% | Added |
| Erste Asset Management GmbH | 14,000 | $413.8K | 0.01% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 13,190 | $390.4K | 0.00% | +13,190 | New |
| UBS Group AG | 12,942 | $383.1K | 0.00% | −15,533−54.5% | Reduced |
| DekaBank Deutsche Girozentrale | 13,200 | $375.0K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 10,533 | $311.8K | 0.00% | +1,400+15.3% | Added |
| Fishman Jay A Ltd | 10,500 | $310.8K | 0.04% | +10,500 | New |
| Marshall Wace, LLP | 9,271 | $274.4K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 8,861 | $262.3K | 0.00% | +39+0.4% | Added |
| Deutsche Bank AG | 8,370 | $247.8K | 0.00% | −6,480−43.6% | Reduced |
| Victory Capital Management Inc | 8,037 | $237.9K | 0.00% | −27,820−77.6% | Reduced |
| Jump Financial, LLC | 7,400 | $219.0K | 0.01% | +7,400 | New |
| Twelve Points Wealth Management LLC | 7,200 | $213.1K | 0.15% | +7,200 | New |
| Bank of America Corp | 5,513 | $163.2K | 0.00% | −3,613−39.6% | Reduced |
| Virtus ETF Advisers LLC | 4,361 | $129.1K | 0.07% | −3,648−45.5% | Reduced |
| HighMark Wealth Management LLC | 4,235 | $125.4K | 0.09% | 00.0% | Unchanged |
| Natixis | 3,613 | $106.9K | 0.00% | +3,613 | New |
| Cutler Group LP | 2,040 | $60.0K | 0.01% | −60−2.9% | Reduced |
| Advisor Group Holdings, Inc. | 1,310 | $38.0K | 0.00% | −100−7.1% | Reduced |
| Tower Research Capital LLC (TRC) | 1,164 | $35.0K | 0.00% | −1,099−48.6% | Reduced |
| Citigroup Inc | 511 | $15.1K | 0.00% | −23−4.3% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 395 | $11.7K | 0.00% | −140−26.2% | Reduced |
| China Universal Asset Management Co., Ltd. | 259 | $7.67K | 0.00% | +20+8.4% | Added |
| Royal Bank of Canada | 211 | $7.00K | 0.00% | +3+1.4% | Added |
| US Bancorp | 234 | $6.93K | 0.00% | 00.0% | Unchanged |
| HealthInvest Partners AB | 226 | $6.69K | 0.01% | +226 | New |
| Rockefeller Capital Management L.P. | 213 | $6.00K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 162 | $4.79K | 0.00% | +162 | New |
| Advisory Services Network, LLC | 115 | $3.40K | 0.00% | +115 | New |
| Daiwa Securities Group Inc. | 103 | $3.00K | 0.00% | +45+77.6% | Added |
| Crewe Advisors LLC | 83 | $2.46K | 0.00% | 00.0% | Unchanged |
| TCI Wealth Advisors, Inc. | 73 | $2.16K | 0.00% | +73 | New |
| Zullo Investment Group, Inc. | 50 | $1.48K | 0.00% | 00.0% | Unchanged |
| Newbridge Financial Services Group, Inc. | 40 | $1.18K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 5 | $148 | 0.00% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 20 | $0 | 0.00% | +20 | New |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −67,625−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −62,667−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −49,500−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −24,033−100.0% | Sold out |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Alps Advisors Inc | 0 | $0 | 0.00% | −16,186−100.0% | Sold out |
| Almanack Investment Partners, LLC. | 0 | $0 | 0.00% | −524−100.0% | Sold out |
| Meeder Asset Management Inc | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| SV Health Investors, LLC | – | – | – | – | Not filed |