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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Bicycle Therapeutics PLC as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
79
−3 vs. Q2 2022
Shares held
23.1M
+433.4K (+1.9%) vs. Q2 2022
Total value
$538.0M
+$156.9M (+41.2%) vs. Q2 2022
New holders
8
22 more added
Sold out
11
29 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 79 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ3 2022: $538.0M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q2 2022.

Institutions holding BCYC in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Deep Track Capital, LP2,900,000$67.5M3.33%00.0%Unchanged
Logos Global Management LP2,000,000$46.5M5.74%+300,000+17.6%Added
Janus Henderson Group PLC1,680,849$39.1M0.03%+306,360+22.3%Added
Samlyn Capital, LLC1,294,085$30.1M0.57%+253,846+24.4%Added
RTW Investments, LP1,276,276$29.7M0.68%00.0%Unchanged
Point72 Asset Management, L.P.1,255,418$29.2M0.13%−189,582−13.1%Reduced
Candriam Luxembourg S.C.A.1,232,254$28.7M0.20%+397,578+47.6%Added
Paradigm Biocapital Advisors LP1,158,686$27.0M3.80%+110,170+10.5%Added
Tybourne Capital Management (HK) Ltd1,041,331$24.2M2.33%−112,795−9.8%Reduced
SV Health Investors, LLC907,032$21.1M65.36%00.0%Unchanged
Morgan Stanley859,851$20.0M0.00%+38,647+4.7%Added
Eventide Asset Management, LLC853,800$19.9M0.39%00.0%Unchanged
Baker Bros. Advisors LP843,814$19.6M0.13%+843,814New
First Light Asset Management, LLC704,721$16.4M1.66%+439+0.1%Added
Sio Capital Management, LLC683,425$15.9M6.78%−5,564−0.8%Reduced
FMR LLC664,806$15.5M0.00%−43,274−6.1%Reduced
Price T Rowe Associates Inc417,340$9.71M0.00%−3,921−0.9%Reduced
AXA S.A.410,640$9.55M0.04%−52,387−11.3%Reduced
Verition Fund Management LLC348,513$8.11M0.11%−50,510−12.7%Reduced
Two Sigma Advisers, LP262,700$6.11M0.02%−152,500−36.7%Reduced
Pura Vida Investments, LLC213,121$4.96M0.75%+30,000+16.4%Added
BlackRock Inc.181,047$4.21M0.00%−10,059−5.3%Reduced
Millennium Management LLC143,046$3.33M0.00%−190,655−57.1%Reduced
HighVista Strategies LLC136,759$3.18M1.82%−14,448−9.6%Reduced
Handelsbanken Fonder AB130,000$3.02M0.02%00.0%Unchanged
JPMorgan Chase & Co125,689$2.92M0.00%+42,231+50.6%Added
DAFNA Capital Management LLC122,200$2.84M0.76%−9,000−6.9%Reduced
Goldman Sachs Group Inc105,291$2.45M0.00%−49,035−31.8%Reduced
Bellevue Group AG98,100$2.28M0.03%+13,700+16.2%Added
Tekla Capital Management LLC88,676$2.06M0.08%+68,611+341.9%Added
Parkman Healthcare Partners LLC81,364$1.89M0.54%+20,938+34.7%Added
ExodusPoint Capital Management, LP78,682$1.83M0.03%−103,443−56.8%Reduced
Voya Investment Management LLC67,747$1.58M0.00%+67,747New
UBS Oconnor LLC67,625$1.57M0.02%+10,000+17.4%Added
Alliancebernstein L.P.63,438$1.48M0.00%−68,868−52.1%Reduced
Voloridge Investment Management, LLC62,667$1.46M0.01%−60,383−49.1%Reduced
Two Sigma Investments, LP49,500$1.15M0.00%−331,154−87.0%Reduced
Citadel Advisors LLC48,404$1.13M0.00%−194,930−80.1%Reduced
Harbor Capital Advisors, Inc.45,667$1.06M0.99%−5,360−10.5%Reduced
L & S Advisors Inc42,765$995.0K0.18%+42,765New
Victory Capital Management Inc35,857$834.0K0.00%+2,445+7.3%Added
UBS Group AG28,475$662.0K0.00%+15,509+119.6%Added
Manufacturers Life Insurance Company, The25,136$597.5K0.00%00.0%Unchanged
Ensign Peak Advisors, Inc24,033$559.0K0.00%+5,773+31.6%Added
Eagle Health Investments LP23,500$547.0K0.13%00.0%Unchanged
AtonRa Partners21,594$502.0K0.49%−1,425−6.2%Reduced
Geode Capital Management, LLC21,420$498.0K0.00%+10,287+92.4%Added
Schonfeld Strategic Advisors LLC20,800$483.0K0.00%−500−2.3%Reduced
Octagon Capital Advisors LP20,000$465.0K0.08%+20,000New
Alps Advisors Inc16,186$376.0K0.00%−1,404−8.0%Reduced
TD Asset Management Inc15,586$370.0K0.00%00.0%Unchanged
Allianz Asset Management GmbH15,200$354.0K0.00%−69,285−82.0%Reduced
Woodstock Corp14,840$345.0K0.05%+4,520+43.8%Added
Deutsche Bank AG14,850$345.0K0.00%+14,850New
Erste Asset Management GmbH14,000$332.8K0.01%00.0%Unchanged
DekaBank Deutsche Girozentrale13,200$300.0K0.00%00.0%Unchanged
Marshall Wace, LLP9,271$216.0K0.00%−70,852−88.4%Reduced
Bank of America Corp9,126$212.0K0.00%−8,171−47.2%Reduced
Legal & General Group Plc9,133$212.0K0.00%00.0%Unchanged
State Street Corp8,822$205.0K0.00%−8,652−49.5%Reduced
Virtus ETF Advisers LLC8,009$186.0K0.07%+63+0.8%Added
HighMark Wealth Management LLC4,235$99.0K0.08%00.0%Unchanged
Tower Research Capital LLC (TRC)2,263$53.0K0.00%+1,184+109.7%Added
Cutler Group LP2,100$48.0K0.01%−400−16.0%Reduced
Advisor Group Holdings, Inc.1,410$33.0K0.00%+460+48.4%Added
Citigroup Inc534$12.0K0.00%−55−9.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)535$12.0K0.00%00.0%Unchanged
Almanack Investment Partners, LLC.524$12.0K0.00%+524New
China Universal Asset Management Co., Ltd.239$6.00K0.00%+239New
US Bancorp234$5.00K0.00%−149−38.9%Reduced
Simplex Trading, LLC242$5.00K0.00%+242New
Royal Bank of Canada208$4.00K0.00%+18+9.5%Added
Rockefeller Capital Management L.P.213$4.00K0.00%00.0%Unchanged
Crewe Advisors LLC83$2.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.58$1.00K0.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.40$1.00K0.00%00.0%Unchanged
Zullo Investment Group, Inc.50$1.00K0.00%00.0%Unchanged
Meeder Asset Management Inc2$00.00%00.0%Unchanged
Parallel Advisors, LLC5$00.00%00.0%Unchanged
Renaissance Technologies LLC0$00.00%−153,200−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−124,696−100.0%Sold out
Acadian Asset Management LLC0$00.00%−56,909−100.0%Sold out
SG Americas Securities, LLC0$00.00%−30,328−100.0%Sold out
Man Group plc0$00.00%–Sold out
Trexquant Investment LP0$00.00%−10,899−100.0%Sold out
Quantbot Technologies LP0$00.00%−3,612−100.0%Sold out
High Net Worth Advisory Group LLC0$00.00%−500−100.0%Sold out
Captrust Financial Advisors0$00.00%−354−100.0%Sold out
BNP Paribas Arbitrage, SA0$00.00%−333−100.0%Sold out
Wells Fargo & Company0$00.00%−1−100.0%Sold out