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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Bicycle Therapeutics PLC as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
97
−7 vs. Q3 2024
Shares held
41.9M
+1.47M (+3.6%) vs. Q3 2024
Total value
$586.5M
−$328.3M (−35.9%) vs. Q3 2024
New holders
16
29 more added
Sold out
23
36 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 97 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ4 2024: $586.5M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q3 2024.

Institutions holding BCYC in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
SBI Securities Co., Ltd.7$980.00%+7New
Steward Partners Investment Advisory, LLC10$1400.00%+10New
Ronald Blue Trust, Inc.11$1540.00%−524−97.9%Reduced
Caitlin John, LLC14$1960.00%00.0%Unchanged
Bell Investment Advisors, Inc22$3080.00%00.0%Unchanged
EverSource Wealth Advisors, LLC24$3360.00%+4+20.0%Added
Federation des caisses Desjardins du Quebec61$8540.00%00.0%Unchanged
Daiwa Securities Group Inc.103$1.00K0.00%00.0%Unchanged
TD Waterhouse Canada Inc.100$1.40K0.00%+100New
AdvisorNet Financial, Inc100$1.40K0.00%+100New
Caitong International Asset Management Co., Ltd148$2.07K0.00%+148New
Jones Financial Companies LLLP150$2.10K0.00%+50+50.0%Added
Winch Advisory Services, LLC172$2.41K0.00%00.0%Unchanged
R Squared Ltd180$2.52K0.00%+180New
FMR LLC316$4.42K0.00%−150,200−99.8%Reduced
Group One Trading, L.P.466$6.52K0.00%+466New
Manchester Capital Management LLC590$8.26K0.00%00.0%Unchanged
Citigroup Inc630$8.82K0.00%−38−5.7%Reduced
BNP Paribas Arbitrage, SA680$9.52K0.00%−118−14.8%Reduced
Advisor Group Holdings, Inc.760$10.6K0.00%−282−27.1%Reduced
GAMMA Investing LLC917$12.8K0.00%−1,109−54.7%Reduced
GF Fund Management Co. Ltd.924$12.9K0.00%+924New
Tower Research Capital LLC (TRC)925$12.9K0.00%+296+47.1%Added
Coppell Advisory Solutions LLC1,076$15.0K0.00%00.0%Unchanged
Rhumbline Advisers1,157$16.2K0.00%+57+5.2%Added
Assetmark, Inc1,260$17.6K0.00%−259−17.1%Reduced
Mirae Asset Global Investments Co., Ltd.1,466$21.3K0.00%+124+9.2%Added
Natixis2,298$33.2K0.00%−437−16.0%Reduced
Barclays PLC2,612$36.6K0.00%+2,345+878.3%Added
Virtus ETF Advisers LLC3,535$49.5K0.02%−254−6.7%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC4,043$56.6K0.00%+4,043New
HighMark Wealth Management LLC4,435$62.1K0.04%00.0%Unchanged
Deutsche Bank AG6,417$89.8K0.00%−1,653−20.5%Reduced
Exchange Traded Concepts, LLC6,707$93.9K0.00%00.0%Unchanged
JPMorgan Chase & Co7,707$107.9K0.00%−717−8.5%Reduced
China Universal Asset Management Co., Ltd.9,329$130.6K0.01%+2,191+30.7%Added
Royal Bank of Canada9,773$137.0K0.00%+9,310+2,010.8%Added
Crossmark Global Holdings, Inc.11,378$159.0K0.00%+11+0.1%Added
The PNC Financial Services Group, Inc.12,900$180.6K0.00%00.0%Unchanged
Horizon Kinetics Asset Management LLC14,396$201.5K0.00%+604+4.4%Added
Erste Asset Management GmbH14,000$203.7K0.00%00.0%Unchanged
Tocqueville Asset Management L.P.14,700$205.8K0.00%−700−4.5%Reduced
Wexford Capital LP17,879$250.3K0.06%−17,000−48.7%Reduced
Jane Street Group, LLC23,991$335.9K0.00%+3,811+18.9%Added
Allianz Asset Management GmbH24,600$344.4K0.00%00.0%Unchanged
Woodstock Corp24,981$349.7K0.03%00.0%Unchanged
DekaBank Deutsche Girozentrale30,000$414.0K0.00%00.0%Unchanged
Geode Capital Management, LLC38,815$543.4K0.00%+480+1.3%Added
Altium Capital Management LP40,352$564.9K0.18%−44,648−52.5%Reduced
Schonfeld Strategic Advisors LLC42,500$595.0K0.00%−380,500−90.0%Reduced
Skandinaviska Enskilda Banken AB (publ)42,729$603.3K0.00%00.0%Unchanged
EntryPoint Capital, LLC43,873$614.2K0.26%+43,873New
Voya Investment Management LLC48,420$677.9K0.00%−56,870−54.0%Reduced
Cubist Systematic Strategies, LLC49,899$698.6K0.01%−28,721−36.5%Reduced
Nan Fung Group Holdings Ltd68,943$965.2K0.83%+37,358+118.3%Added
UBS Oconnor LLC80,236$1.12M0.03%+44,260+123.0%Added
State Street Corp87,765$1.23M0.00%+1,494+1.7%Added
Springhill Fund Asset Management (HK) Co Ltd116,400$1.63M2.65%+116,400New
DAFNA Capital Management LLC120,799$1.69M0.43%−1,401−1.1%Reduced
HighVista Strategies LLC124,430$1.74M0.65%−15,114−10.8%Reduced
Manufacturers Life Insurance Company, The124,497$1.74M0.00%−5,208−4.0%Reduced
Harbor Capital Advisors, Inc.131,505$1.84M0.08%−2,202−1.6%Reduced
UBS Group AG132,361$1.85M0.00%+120,295+997.0%Added
Silvercrest Asset Management Group LLC137,740$1.93M0.01%−1,353−1.0%Reduced
Legal & General Group Plc139,075$1.95M0.00%−99,741−41.8%Reduced
Citadel Advisors LLC144,230$2.02M0.00%+41,481+40.4%Added
Caption Management, LLC163,076$2.28M0.09%+163,076New
Millennium Management LLC176,757$2.47M0.00%+176,757New
Perceptive Advisors LLC197,108$2.76M0.08%−58,886−23.0%Reduced
Handelsbanken Fonder AB215,900$3.02M0.01%−2,800−1.3%Reduced
TD Asset Management Inc216,016$3.02M0.00%−5,400−2.4%Reduced
Aquilo Capital Management, LLC221,911$3.11M5.32%+40,000+22.0%Added
Pinnacle Associates Ltd226,742$3.17M0.04%+226,742New
Palo Alto Investors LP248,934$3.49M0.54%+189,352+317.8%Added
Renaissance Technologies LLC269,500$3.77M0.01%−3,100−1.1%Reduced
Verition Fund Management LLC280,327$3.92M0.02%+68,176+32.1%Added
Platinum Investment Management Ltd309,059$4.33M0.25%+36,910+13.6%Added
Parkman Healthcare Partners LLC352,481$4.93M0.66%−92,915−20.9%Reduced
BlackRock, Inc.365,408$5.12M0.00%−54,355−12.9%Reduced
Bank of America Corp392,859$5.50M0.00%+7,994+2.1%Added
Principal Financial Group Inc406,470$5.69M0.00%−36,671−8.3%Reduced
Long Focus Capital Management, LLC543,092$7.60M0.58%+543,092New
AXA S.A.553,959$7.76M0.02%−440−0.1%Reduced
Morgan Stanley862,137$12.1M0.00%−487,757−36.1%Reduced
EcoR1 Capital, LLC910,000$12.7M0.51%00.0%Unchanged
Candriam Luxembourg S.C.A.1,087,876$15.2M0.09%+37,278+3.5%Added
Ra Capital Management, L.P.1,093,477$15.3M0.20%−1,159,523−51.5%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,155,651$16.2M0.04%+395,764+52.1%Added
Tybourne Capital Management (HK) Ltd1,269,535$17.8M4.46%−125,000−9.0%Reduced
Deep Track Capital, LP1,276,081$17.9M0.67%−2,271,920−64.0%Reduced
Price T Rowe Associates Inc1,585,127$22.2M0.00%−136,913−8.0%Reduced
Siren, L.L.C.1,839,398$25.8M1.14%+1,839,398New
Armistice Capital, LLC2,196,000$30.7M0.71%+240,000+12.3%Added
Westfield Capital Management Co LP2,610,337$36.5M0.16%+759,392+41.0%Added
FCPM III Services B.V.3,452,330$48.3M8.16%+1,112,369+47.5%Added
Point72 Asset Management, L.P.4,554,900$63.8M0.17%+3,655,101+406.2%Added
Baker Bros. Advisors LP10,885,357$152.4M1.63%+1,485,397+15.8%Added
Polar Capital Holdings Plc0$00.00%−1,002,780−100.0%Sold out
First Light Asset Management, LLC0$00.00%−967,006−100.0%Sold out
Camber Capital Management LP0$00.00%−915,000−100.0%Sold out