Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Bicycle Therapeutics PLC as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 105
- +4 vs. Q4 2021
- Shares held
- 20.2M
- −1.39M (−6.5%) vs. Q4 2021
- Total value
- $884.5M
- −$427.4M (−32.6%) vs. Q4 2021
- New holders
- 24
- 27 more added
- Sold out
- 20
- 42 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Parallel Advisors, LLC | 5 | $0 | 0.00% | 00.0% | Unchanged |
| Meeder Asset Management Inc | 2 | $0 | 0.00% | +2 | New |
| Kayne Anderson Rudnick Investment Management LLC | 30 | $1.00K | 0.00% | +30 | New |
| CWM, LLC | 28 | $1.00K | 0.00% | +28 | New |
| Zullo Investment Group, Inc. | 50 | $2.00K | 0.00% | 00.0% | Unchanged |
| Newbridge Financial Services Group, Inc. | 40 | $2.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 58 | $3.00K | 0.00% | 00.0% | Unchanged |
| American Portfolios Advisors | 96 | $4.21K | 0.00% | −18−15.8% | Reduced |
| Rockefeller Capital Management L.P. | 165 | $7.00K | 0.00% | 00.0% | Unchanged |
| CIBC Private Wealth Group, LLC | 183 | $8.00K | 0.00% | +183 | New |
| US Bancorp | 234 | $10.0K | 0.00% | −137−36.9% | Reduced |
| Royal Bank of Canada | 247 | $11.0K | 0.00% | +96+63.6% | Added |
| Leonteq Securities AG | 270 | $11.8K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 354 | $16.0K | 0.00% | −1,906−84.3% | Reduced |
| Tower Research Capital LLC (TRC) | 396 | $17.0K | 0.00% | −3,331−89.4% | Reduced |
| High Net Worth Advisory Group LLC | 500 | $22.0K | 0.01% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 535 | $23.0K | 0.00% | +535 | New |
| Citigroup Inc | 748 | $33.0K | 0.00% | −54−6.7% | Reduced |
| Prospera Financial Services Inc | 1,999 | $88.0K | 0.00% | +1,999 | New |
| Barclays PLC | 2,129 | $93.0K | 0.00% | −1,471−40.9% | Reduced |
| Cutler Group LP | 2,550 | $111.0K | 0.01% | +1,300+104.0% | Added |
| Virtus ETF Advisers LLC | 2,987 | $131.0K | 0.06% | −179−5.7% | Reduced |
| Bank of America Corp | 3,110 | $136.0K | 0.00% | +586+23.2% | Added |
| Advisor Group Holdings, Inc. | 4,039 | $176.0K | 0.00% | −295−6.8% | Reduced |
| HighMark Wealth Management LLC | 4,235 | $186.0K | 0.12% | −90−2.1% | Reduced |
| Claro Advisors LLC | 3,637 | $221.0K | 0.08% | 00.0% | Unchanged |
| Shilanski & Associates, Inc. | 5,502 | $241.0K | 0.10% | +346+6.7% | Added |
| Truist Financial Corp | 6,436 | $282.0K | 0.00% | −469−6.8% | Reduced |
| TownSquare Capital, LLC | 7,088 | $311.0K | 0.01% | −94−1.3% | Reduced |
| Twelve Points Wealth Management LLC | 7,100 | $312.0K | 0.23% | 00.0% | Unchanged |
| Personal Cfo Solutions, LLC | 7,455 | $327.0K | 0.06% | −12−0.2% | Reduced |
| Engineers Gate Manager LP | 7,770 | $341.0K | 0.01% | +7,770 | New |
| Jane Street Group, LLC | 7,991 | $351.0K | 0.00% | −5,395−40.3% | Reduced |
| Schonfeld Strategic Advisors LLC | 8,000 | $351.0K | 0.00% | +8,000 | New |
| Qube Research & Technologies Ltd | 8,806 | $386.0K | 0.00% | +8,806 | New |
| Wrapmanager Inc | 8,835 | $388.0K | 0.10% | −231−2.5% | Reduced |
| UBS Group AG | 8,884 | $389.0K | 0.00% | +7,992+896.0% | Added |
| JPMorgan Chase & Co | 9,903 | $434.0K | 0.00% | +7,075+250.2% | Added |
| Vestmark Advisory Solutions, Inc. | 9,906 | $435.0K | 0.02% | +157+1.6% | Added |
| Tekla Capital Management LLC | 10,086 | $443.0K | 0.02% | +10,086 | New |
| Woodstock Corp | 10,320 | $453.0K | 0.05% | −362−3.4% | Reduced |
| Marshall Wace, LLP | 10,619 | $466.0K | 0.00% | −39,779−78.9% | Reduced |
| State Street Corp | 10,687 | $469.0K | 0.00% | +2,333+27.9% | Added |
| Geode Capital Management, LLC | 11,133 | $488.0K | 0.00% | +1,253+12.7% | Added |
| Legal & General Group Plc | 11,266 | $495.0K | 0.00% | +1,206+12.0% | Added |
| Squarepoint Ops LLC | 11,700 | $513.0K | 0.00% | +3,500+42.7% | Added |
| DekaBank Deutsche Girozentrale | 13,200 | $562.0K | 0.00% | +1,200+10.0% | Added |
| Erste Asset Management GmbH | 14,000 | $595.6K | 0.01% | 00.0% | Unchanged |
| Pentwater Capital Management LP | 14,000 | $614.0K | 0.01% | −25,500−64.6% | Reduced |
| Cinctive Capital Management LP | 15,000 | $658.0K | 0.03% | +15,000 | New |
| AtonRa Partners | 16,625 | $730.0K | 0.40% | +16,625 | New |
| Woodline Partners LP | 17,954 | $788.0K | 0.01% | +17,954 | New |
| Ensign Peak Advisors, Inc | 18,260 | $801.0K | 0.00% | 00.0% | Unchanged |
| HighVista Strategies LLC | 18,298 | $803.0K | 0.51% | +18,298 | New |
| Manufacturers Life Insurance Company, The | 19,533 | $830.9K | 0.00% | +19,533 | New |
| Vident Investment Advisory, LLC | 21,572 | $947.0K | 0.02% | +3,639+20.3% | Added |
| Jump Financial, LLC | 28,176 | $1.24M | 0.05% | −3,031−9.7% | Reduced |
| Harbor Capital Advisors, Inc. | 28,942 | $1.27M | 0.60% | −5,658−16.4% | Reduced |
| TD Asset Management Inc | 29,086 | $1.28M | 0.00% | −2,500−7.9% | Reduced |
| SG Americas Securities, LLC | 30,379 | $1.33M | 0.01% | +30,379 | New |
| Stifel Financial Corp | 31,746 | $1.39M | 0.00% | −3,213−9.2% | Reduced |
| Acadian Asset Management LLC | 35,959 | $1.58M | 0.01% | −142,580−79.9% | Reduced |
| Envestnet Asset Management Inc | 36,164 | $1.59M | 0.00% | −5,128−12.4% | Reduced |
| Bellevue Group AG | 36,500 | $1.60M | 0.02% | −17,200−32.0% | Reduced |
| Caption Management, LLC | 38,013 | $1.67M | 0.11% | +38,013 | New |
| Fred Alger Management, LLC | 39,246 | $1.72M | 0.01% | +39,246 | New |
| LMR Partners LLP | 40,283 | $1.77M | 0.03% | +283+0.7% | Added |
| Boothbay Fund Management, LLC | 46,770 | $2.05M | 0.07% | −16,646−26.2% | Reduced |
| Sio Capital Management, LLC | 52,788 | $2.32M | 0.93% | −1,212−2.2% | Reduced |
| DAFNA Capital Management LLC | 53,200 | $2.33M | 0.61% | +53,200 | New |
| Parkman Healthcare Partners LLC | 57,295 | $2.51M | 0.74% | −7,505−11.6% | Reduced |
| Renaissance Technologies LLC | 64,399 | $2.83M | 0.00% | −8,780−12.0% | Reduced |
| Morgan Stanley | 87,917 | $3.86M | 0.00% | −62,095−41.4% | Reduced |
| Ghost Tree Capital, LLC | 100,000 | $4.39M | 2.17% | +100,000 | New |
| Altium Capital Management LP | 120,000 | $5.27M | 1.84% | −52,000−30.2% | Reduced |
| Dorsey Wright & Associates | 126,982 | $5.57M | 1.29% | −3,744−2.9% | Reduced |
| Two Sigma Advisers, LP | 128,800 | $5.65M | 0.02% | +31,600+32.5% | Added |
| Handelsbanken Fonder AB | 130,000 | $5.70M | 0.03% | +50,000+62.5% | Added |
| Verition Fund Management LLC | 134,204 | $5.89M | 0.11% | −30,511−18.5% | Reduced |
| AXA S.A. | 145,254 | $6.37M | 0.02% | +20.0% | Added |
| Goldman Sachs Group Inc | 163,265 | $7.16M | 0.00% | +142,578+689.2% | Added |
| Millennium Management LLC | 163,367 | $7.17M | 0.01% | +10,635+7.0% | Added |
| Sofinnova Investments, Inc. | 163,559 | $7.18M | 0.60% | +163,559 | New |
| Opaleye Management Inc. | 175,000 | $7.68M | 2.38% | +175,000 | New |
| Two Sigma Investments, LP | 177,322 | $7.78M | 0.02% | +25,961+17.2% | Added |
| BlackRock Inc. | 190,129 | $8.34M | 0.00% | −13,866−6.8% | Reduced |
| Driehaus Capital Management LLC | 229,290 | $10.1M | 0.12% | −37,742−14.1% | Reduced |
| Samlyn Capital, LLC | 426,543 | $18.7M | 0.28% | +117,428+38.0% | Added |
| Ikarian Capital, LLC | 478,784 | $21.0M | 6.39% | −134,342−21.9% | Reduced |
| Victory Capital Management Inc | 551,415 | $23.5M | 0.02% | −17,153−3.0% | Reduced |
| EcoR1 Capital, LLC | 547,453 | $24.0M | 0.75% | +547,453 | New |
| Great Point Partners LLC | 550,592 | $24.2M | 5.85% | +350,592+175.3% | Added |
| Frazier Life Sciences Management, L.P. | 603,521 | $26.5M | 2.26% | +603,521 | New |
| Loomis Sayles & Co L P | 643,775 | $28.2M | 0.04% | +73,728+12.9% | Added |
| Price T Rowe Associates Inc | 685,876 | $30.1M | 0.00% | −110,138−13.8% | Reduced |
| FMR LLC | 803,748 | $35.3M | 0.00% | −657,134−45.0% | Reduced |
| First Light Asset Management, LLC | 890,174 | $39.1M | 3.45% | −110,609−11.1% | Reduced |
| SV Health Investors, LLC | 917,218 | $40.2M | 48.61% | −936−0.1% | Reduced |
| Logos Global Management LP | 950,000 | $41.7M | 5.40% | +80,000+9.2% | Added |
| Tybourne Capital Management (HK) Ltd | 1,154,126 | $50.6M | 3.00% | −899,678−43.8% | Reduced |