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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Bicycle Therapeutics PLC as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
95
−2 vs. Q4 2024
Shares held
41.7M
−155.0K (−0.4%) vs. Q4 2024
Total value
$354.4M
−$232.1M (−39.6%) vs. Q4 2024
New holders
15
28 more added
Sold out
17
30 more reduced

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 95 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ1 2025: $354.4M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q4 2024.

Institutions holding BCYC in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Caitong International Asset Management Co., Ltd2$170.00%−146−98.6%Reduced
SBI Securities Co., Ltd.6$510.00%−1−14.3%Reduced
Steward Partners Investment Advisory, LLC10$850.00%00.0%Unchanged
Ronald Blue Trust, Inc.11$930.00%00.0%Unchanged
EverSource Wealth Advisors, LLC13$1100.00%−11−45.8%Reduced
Advisor Group Holdings, Inc.18$1520.00%−742−97.6%Reduced
Bell Investment Advisors, Inc22$1870.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec61$5180.00%00.0%Unchanged
TD Waterhouse Canada Inc.100$7850.00%00.0%Unchanged
Daiwa Securities Group Inc.103$1.00K0.00%00.0%Unchanged
Group One Trading, L.P.166$1.41K0.00%−300−64.4%Reduced
Winch Advisory Services, LLC172$1.46K0.00%00.0%Unchanged
Boston Private Wealth LLC210$1.78K0.00%+210New
Jones Financial Companies LLLP250$2.24K0.00%+100+66.7%Added
FMR LLC316$2.68K0.00%00.0%Unchanged
HighMark Wealth Management LLC435$3.69K0.00%−4,000−90.2%Reduced
Simplex Trading, LLC571$4.00K0.00%+571New
Manchester Capital Management LLC590$5.01K0.00%00.0%Unchanged
Citigroup Inc689$5.85K0.00%+59+9.4%Added
GAMMA Investing LLC1,058$8.98K0.00%+141+15.4%Added
Tower Research Capital LLC (TRC)1,081$9.18K0.00%+156+16.9%Added
GF Fund Management Co. Ltd.1,126$9.56K0.00%+202+21.9%Added
BNP Paribas Arbitrage, SA1,211$10.3K0.00%+531+78.1%Added
Assetmark, Inc1,282$10.9K0.00%+22+1.7%Added
Rhumbline Advisers1,304$11.1K0.00%+147+12.7%Added
Mirae Asset Global Investments Co., Ltd.1,464$13.1K0.00%−2−0.1%Reduced
Natixis2,126$17.9K0.00%−172−7.5%Reduced
Barclays PLC3,308$28.1K0.00%+696+26.6%Added
UBS Asset Management Americas Inc5,100$43.3K0.00%+5,100New
Deutsche Bank AG6,417$54.5K0.00%00.0%Unchanged
JPMorgan Chase & Co7,044$59.8K0.00%−663−8.6%Reduced
Virtus Investment Advisers, Inc.8,162$69.3K0.02%+8,162New
China Universal Asset Management Co., Ltd.8,833$75.0K0.01%−496−5.3%Reduced
SEI Investments Co10,637$90.3K0.00%+10,637New
Crossmark Global Holdings, Inc.11,400$96.8K0.00%+22+0.2%Added
Gsa Capital Partners LLP11,952$101.0K0.01%+11,952New
Envestnet Asset Management Inc12,420$105.4K0.00%+12,420New
Exchange Traded Concepts, LLC12,764$108.4K0.00%+6,057+90.3%Added
The PNC Financial Services Group, Inc.13,080$111.0K0.00%+180+1.4%Added
Cerity Partners LLC13,350$113.3K0.00%+13,350New
Horizon Kinetics Asset Management LLC14,396$122.2K0.00%00.0%Unchanged
Erste Asset Management GmbH14,000$125.6K0.00%00.0%Unchanged
Portland Investment Counsel Inc.15,000$127.3K0.04%+15,000New
Royal Bank of Canada17,940$152.0K0.00%+8,167+83.6%Added
Tocqueville Asset Management L.P.18,300$155.4K0.00%+3,600+24.5%Added
Geode Capital Management, LLC21,377$181.5K0.00%−17,438−44.9%Reduced
Woodstock Corp24,981$212.1K0.02%00.0%Unchanged
Goldman Sachs Group Inc25,192$213.9K0.00%+25,192New
EntryPoint Capital, LLC28,857$245.0K0.11%−15,016−34.2%Reduced
DekaBank Deutsche Girozentrale30,000$256.0K0.00%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)42,729$363.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC47,249$401.1K0.01%−2,650−5.3%Reduced
Moore Capital Management, LP50,000$424.5K0.01%+50,000New
Shay Capital LLC60,000$509.4K0.15%+60,000New
Nan Fung Group Holdings Ltd68,943$585.3K0.48%00.0%Unchanged
UBS Group AG72,702$617.2K0.00%−59,659−45.1%Reduced
DAFNA Capital Management LLC80,799$686.0K0.19%−40,000−33.1%Reduced
Caption Management, LLC81,559$692.4K0.03%−81,517−50.0%Reduced
State Street Corp85,653$727.2K0.00%−2,112−2.4%Reduced
Acadian Asset Management LLC126,062$1.06M0.00%+126,062New
Citadel Advisors LLC130,070$1.10M0.00%−14,160−9.8%Reduced
Legal & General Group Plc135,658$1.17M0.00%−3,417−2.5%Reduced
Manufacturers Life Insurance Company, The138,249$1.17M0.00%+13,752+11.0%Added
Harbor Capital Advisors, Inc.148,129$1.26M0.06%+16,624+12.6%Added
UBS Oconnor LLC148,722$1.26M0.03%+68,486+85.4%Added
Aquilo Capital Management, LLC171,695$1.46M3.93%−50,216−22.6%Reduced
TD Asset Management Inc193,092$1.64M0.00%−22,924−10.6%Reduced
Pinnacle Associates Ltd214,278$1.82M0.03%−12,464−5.5%Reduced
Handelsbanken Fonder AB215,900$1.83M0.01%00.0%Unchanged
Palo Alto Investors LP248,934$2.11M0.40%00.0%Unchanged
Silvercrest Asset Management Group LLC265,693$2.26M0.02%+127,953+92.9%Added
Platinum Investment Management Ltd287,599$2.44M0.14%−21,460−6.9%Reduced
Renaissance Technologies LLC301,500$2.56M0.00%+32,000+11.9%Added
BlackRock, Inc.322,876$2.74M0.00%−42,532−11.6%Reduced
Woodline Partners LP363,751$3.09M0.02%+363,751New
Jefferies Financial Group Inc.408,889$3.47M0.06%+408,889New
Millennium Management LLC453,428$3.85M0.00%+276,671+156.5%Added
AXA S.A.553,682$4.70M0.02%−277−0.1%Reduced
Bank of America Corp563,559$4.78M0.00%+170,700+43.5%Added
Tybourne Capital Management (HK) Ltd576,343$4.89M20.77%−693,192−54.6%Reduced
Principal Financial Group Inc631,260$5.36M0.00%+224,790+55.3%Added
Deep Track Capital, LP767,016$6.51M0.21%−509,065−39.9%Reduced
EcoR1 Capital, LLC910,000$7.73M0.46%00.0%Unchanged
Morgan Stanley999,837$8.49M0.00%+137,700+16.0%Added
Ra Capital Management, L.P.1,093,477$9.28M0.16%00.0%Unchanged
Candriam Luxembourg S.C.A.1,205,207$10.2M0.06%+117,331+10.8%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,219,688$10.4M0.03%+64,037+5.5%Added
Long Focus Capital Management, LLC1,293,753$11.0M0.75%+750,661+138.2%Added
Price T Rowe Associates Inc1,536,584$13.0M0.00%−48,543−3.1%Reduced
Siren, L.L.C.1,812,752$15.4M0.87%−26,646−1.4%Reduced
Westfield Capital Management Co LP2,657,305$22.6M0.11%+46,968+1.8%Added
Armistice Capital, LLC2,672,000$22.7M0.61%+476,000+21.7%Added
FCPM III Services B.V.3,452,330$29.3M7.08%00.0%Unchanged
Point72 Asset Management, L.P.3,692,069$31.3M0.09%−862,831−18.9%Reduced
Baker Bros. Advisors LP10,885,357$92.4M1.02%00.0%Unchanged
Parkman Healthcare Partners LLC0$00.00%−352,481−100.0%Sold out
Verition Fund Management LLC0$00.00%−280,327−100.0%Sold out
Perceptive Advisors LLC0$00.00%−197,108−100.0%Sold out
HighVista Strategies LLC0$00.00%−124,430−100.0%Sold out
Springhill Fund Asset Management (HK) Co Ltd0$00.00%−116,400−100.0%Sold out