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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Taysha Gene Therapies, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
208
+19 vs. Q1 2026
Shares held
299.6M
+34.0M (+12.8%) vs. Q1 2026
Total value
$2.03B
+$851.2M (+72.0%) vs. Q1 2026
New holders
41
98 more added
Sold out
22
41 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 208 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ2 2026: $2.03B
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q1 2026.

Institutions holding TSHA in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
RTW Investments, LP13,560,258$92.3M0.79%−119,990−0.9%Reduced
Morgan Stanley16,487,479$112.3M0.01%−1,477,892−8.2%Reduced
Vestal Point Capital, LP19,415,000$132.2M3.09%+1,415,000+7.9%Added
BlackRock, Inc.20,691,927$140.9M0.00%+2,326,319+12.7%Added
Goldman Sachs Group Inc22,713,118$154.7M0.02%+343,473+1.5%Added
Ra Capital Management, L.P.23,555,648$160.4M1.39%00.0%Unchanged
Avoro Capital Advisors LLC23,888,888$162.7M1.46%+2,188,888+10.1%Added
GordonMD Global Investments LP723,185––−14,365−1.9%Reduced
Deerfield Management Company, L.P. (Series C)0$00.00%−2,722,165−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−461,856−100.0%Sold out
Renaissance Technologies LLC0$00.00%−413,203−100.0%Sold out
Superstring Capital Management LP0$00.00%−258,269−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−143,575−100.0%Sold out
VARCOV Co.0$00.00%−58,511−100.0%Sold out
Abacus Wealth Partners, LLC0$00.00%−58,241−100.0%Sold out
Legato Capital Management LLC0$00.00%−21,782−100.0%Sold out
Scientech Research LLC0$00.00%−21,040−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−15,100−100.0%Sold out
Virtu Financial LLC0$00.00%−13,346−100.0%Sold out
Allegheny Financial Group LTD0$00.00%−12,000−100.0%Sold out
CIBC Asset Management Inc0$00.00%−11,959−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−11,486−100.0%Sold out
R Squared Ltd0$00.00%−11,276−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−10,740−100.0%Sold out
Quantbot Technologies LP0$00.00%−524−100.0%Sold out
Sound Income Strategies, LLC0$00.00%−325−100.0%Sold out
Root Financial Partners, LLC0$00.00%−72−100.0%Sold out
MAI Capital Management0$00.00%−13−100.0%Sold out
Assetmark, Inc0$00.00%−8−100.0%Sold out
Ameritas Advisory Services, LLC0$00.00%−1−100.0%Sold out
Janus Henderson Group PLC––––Not filed
CWM, LLC––––Not filed