Taysha Gene Therapies, Inc.
TSHA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001806310
In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Taysha Gene Therapies, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 155
- +8 vs. Q2 2025
- Shares held
- 264.6M
- +6.95M (+2.7%) vs. Q2 2025
- Total value
- $865.6M
- +$270.3M (+45.4%) vs. Q2 2025
- New holders
- 28
- 61 more added
- Sold out
- 20
- 34 more reduced
3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 208 | $2.03B |
| Q1 2026 | 191 | $1.18B |
| Q4 2025 | 195 | $1.48B |
| Q3 2025 | 155 | $865.6M |
| Q2 2025 | 150 | $595.4M |
| Q1 2025 | 127 | $232.0M |
| Q4 2024 | 131 | $289.8M |
| Q3 2024 | 119 | $315.5M |
| Q2 2024 | 107 | $354.3M |
| Q1 2024 | 109 | $402.2M |
| Q4 2023 | 87 | $230.3M |
| Q3 2023 | 63 | $410.6M |
| Q2 2023 | 39 | $9.05M |
| Q1 2023 | 44 | $13.3M |
| Q4 2022 | 52 | $43.8M |
| Q3 2022 | 54 | $27.0M |
| Q2 2022 | 59 | $54.7M |
| Q1 2022 | 71 | $110.9M |
| Q4 2021 | 65 | $215.6M |
| Q3 2021 | 48 | $361.9M |
| Q2 2021 | 49 | $388.6M |
| Q1 2021 | 46 | $358.5M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Prudential Financial Inc | 28,345 | $92.7K | 0.00% | +5,555+24.4% | Added |
| Leonteq Securities AG | 27,999 | $91.6K | 0.00% | 00.0% | Unchanged |
| Sender Co & Partners, Inc. | 27,121 | $88.7K | 0.03% | +27,121 | New |
| Ethic Inc. | 25,784 | $84.3K | 0.00% | −2,191−7.8% | Reduced |
| Victory Capital Management Inc | 25,600 | $83.7K | 0.00% | +108+0.4% | Added |
| Cambridge Investment Research Advisors, Inc. | 23,690 | $77.0K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 23,149 | $75.7K | 0.00% | +4,754+25.8% | Added |
| CIBC Bancorp USA Inc. | 22,643 | $74.0K | 0.00% | +22,643 | New |
| Susquehanna International Group, LLP | 21,742 | $71.1K | 0.00% | −190,830−89.8% | Reduced |
| Daiwa Securities Group Inc. | 21,820 | $71.0K | 0.00% | −2,021−8.5% | Reduced |
| Lee Financial Co | 20,000 | $65.4K | 0.01% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 18,165 | $59.4K | 0.00% | +18,165 | New |
| Xponance, Inc. | 16,575 | $54.2K | 0.00% | +3,738+29.1% | Added |
| DRW Securities, LLC | 16,389 | $53.3K | 0.00% | +16,389 | New |
| Principal Financial Group Inc | 16,251 | $53.1K | 0.00% | +4,091+33.6% | Added |
| Cetera Investment Advisers | 16,162 | $52.9K | 0.00% | +16,162 | New |
| R Squared Ltd | 16,094 | $52.6K | 0.02% | +16,094 | New |
| Ameritas Investment Partners, Inc. | 15,672 | $51.2K | 0.00% | 00.0% | Unchanged |
| Allegheny Financial Group LTD | 15,000 | $49.0K | 0.01% | +15,000 | New |
| Bank of Montreal | 13,668 | $44.7K | 0.00% | +13,668 | New |
| CWM, LLC | 12,885 | $42.0K | 0.00% | −61−0.5% | Reduced |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 12,200 | $39.9K | 0.06% | +12,200 | New |
| Mackenzie Financial Corp | 11,214 | $36.7K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 10,546 | $34.5K | 0.00% | +443+4.4% | Added |
| California State Teachers Retirement System | 10,373 | $33.9K | 0.00% | −2,262−17.9% | Reduced |
| Aigen Investment Management, LP | 10,367 | $33.9K | 0.01% | +10,367 | New |
| Capital Investment Advisors, LLC | 10,000 | $32.7K | 0.00% | 00.0% | Unchanged |
| St Germain D J Co Inc | 9,633 | $31.5K | 0.00% | +4,333+81.8% | Added |
| Tower Research Capital LLC (TRC) | 6,607 | $21.6K | 0.00% | −10,999−62.5% | Reduced |
| Nisa Investment Advisors, LLC | 5,872 | $19.2K | 0.00% | +2,125+56.7% | Added |
| GF Fund Management Co. Ltd. | 5,869 | $19.2K | 0.00% | +621+11.8% | Added |
| Amalgamated Bank | 5,534 | $18.0K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 5,000 | $16.4K | 0.00% | +5,000 | New |
| FNY Investment Advisers, LLC | 4,289 | $14.0K | 0.00% | +4,289 | New |
| Wexford Capital LP | 3,500 | $11.4K | 0.00% | +3,500 | New |
| Caitong International Asset Management Co., Ltd | 3,204 | $10.5K | 0.01% | +1,057+49.2% | Added |
| Simplex Trading, LLC | 2,722 | $8.00K | 0.00% | −541−16.6% | Reduced |
| Optiver Holding B.V. | 2,269 | $7.42K | 0.00% | +204+9.9% | Added |
| Group One Trading, L.P. | 1,754 | $5.74K | 0.00% | +1,754 | New |
| The PNC Financial Services Group, Inc. | 1,308 | $4.28K | 0.00% | +308+30.8% | Added |
| Aster Capital Management (DIFC) Ltd | 1,280 | $4.19K | 0.00% | +1,280 | New |
| US Bancorp | 912 | $2.98K | 0.00% | −63−6.5% | Reduced |
| Clearstead Advisors, LLC | 690 | $2.26K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 515 | $1.68K | 0.00% | +107+26.2% | Added |
| Essential Partners LLC | 327 | $1.07K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 280 | $916 | 0.00% | 00.0% | Unchanged |
| Morton Brown Family Wealth, LLC | 260 | $850 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 215 | $704 | 0.00% | +215 | New |
| Advisor Group Holdings, Inc. | 134 | $426 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 91 | $298 | 0.00% | −114−55.6% | Reduced |
| Farther Finance Advisors, LLC | 55 | $180 | 0.00% | +55 | New |
| True Wealth Design, LLC | 30 | $99 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 16 | $52 | 0.00% | −64−80.0% | Reduced |
| IFP Advisors, Inc | 14 | $46 | 0.00% | 00.0% | Unchanged |
| Capital Advisors, Ltd. LLC | 79 | $0 | 0.00% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 0 | $0 | 0.00% | −3,217,449−100.0% | Sold out |
| MPM Oncology Impact Management LP | 0 | $0 | 0.00% | −2,953,562−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −320,737−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −148,357−100.0% | Sold out |
| Los Angeles Capital Management LLC | 0 | $0 | 0.00% | −117,740−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −72,900−100.0% | Sold out |
| EntryPoint Capital, LLC | 0 | $0 | 0.00% | −69,109−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −54,900−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −25,252−100.0% | Sold out |
| State Board of Administration of Florida Retirement System | 0 | $0 | 0.00% | −22,700−100.0% | Sold out |
| May Hill Capital, LLC | 0 | $0 | 0.00% | −16,051−100.0% | Sold out |
| Howard Capital Management Inc. | 0 | $0 | 0.00% | −14,165−100.0% | Sold out |
| Marex Group plc | 0 | $0 | 0.00% | −12,500−100.0% | Sold out |
| Ieq Capital, LLC | 0 | $0 | 0.00% | −10,063−100.0% | Sold out |
| Atticus Wealth Management, LLC | 0 | $0 | 0.00% | −7,425−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −4,441−100.0% | Sold out |
| Raymond James Financial Inc | 0 | $0 | 0.00% | −3,605−100.0% | Sold out |
| Headlands Technologies LLC | 0 | $0 | 0.00% | −3,037−100.0% | Sold out |
| Rothschild Investment LLC | 0 | $0 | 0.00% | −105−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −48−100.0% | Sold out |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| E Fund Management Co., Ltd. | – | – | – | – | Not filed |
| Bordeaux Wealth Advisors LLC | – | – | – | – | Not filed |