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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Taysha Gene Therapies, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
150
+24 vs. Q1 2025
Shares held
257.7M
+90.9M (+54.5%) vs. Q1 2025
Total value
$595.4M
+$363.4M (+156.7%) vs. Q1 2025
New holders
44
48 more added
Sold out
20
34 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 150 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ2 2025: $595.4M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q1 2025.

Institutions holding TSHA in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Cambridge Investment Research Advisors, Inc.23,690$55.0K0.00%+200+0.9%Added
Daiwa Securities Group Inc.23,841$55.0K0.00%+23,150+3,350.2%Added
Prudential Financial Inc22,790$52.6K0.00%+7,650+50.5%Added
State Board of Administration of Florida Retirement System22,700$52.4K0.00%00.0%Unchanged
New York State Common Retirement Fund21,100$48.7K0.00%00.0%Unchanged
CIBC World Markets Corp20,417$47.2K0.00%−18,480−47.5%Reduced
Lee Financial Co20,000$46.2K0.01%00.0%Unchanged
BNP Paribas Arbitrage, SA18,591$42.9K0.00%+6,350+51.9%Added
Legal & General Group Plc18,395$42.5K0.00%−1,563−7.8%Reduced
Tower Research Capital LLC (TRC)17,606$40.7K0.00%+10,742+156.5%Added
May Hill Capital, LLC16,051$37.1K0.01%+16,051New
Ameritas Investment Partners, Inc.15,672$36.2K0.00%00.0%Unchanged
Howard Capital Management Inc.14,165$32.7K0.00%00.0%Unchanged
E Fund Management Co., Ltd.13,214$30.5K0.00%+13,214New
CWM, LLC12,946$30.0K0.00%+2,419+23.0%Added
Xponance, Inc.12,837$29.7K0.00%+198+1.6%Added
California State Teachers Retirement System12,635$29.2K0.00%00.0%Unchanged
Marex Group plc12,500$28.9K0.00%00.0%Unchanged
Principal Financial Group Inc12,160$28.1K0.00%−1,829−13.1%Reduced
Mackenzie Financial Corp11,214$25.9K0.00%+1,214+12.1%Added
Mirae Asset Global Investments Co., Ltd.10,103$23.3K0.00%+3,731+58.6%Added
Ieq Capital, LLC10,063$23.2K0.00%+10,063New
Bordeaux Wealth Advisors LLC10,058$23.2K0.00%−51−0.5%Reduced
Capital Investment Advisors, LLC10,000$23.1K0.00%00.0%Unchanged
Atticus Wealth Management, LLC7,425$17.2K0.00%00.0%Unchanged
Amalgamated Bank5,534$13.0K0.00%00.0%Unchanged
St Germain D J Co Inc5,300$12.2K0.00%+5,300New
GF Fund Management Co. Ltd.5,248$12.1K0.00%00.0%Unchanged
Point72 (DIFC) Ltd4,441$10.3K0.00%−11,087−71.4%Reduced
Nisa Investment Advisors, LLC3,747$8.66K0.00%−483−11.4%Reduced
Raymond James Financial Inc3,605$8.33K0.00%+3,605New
Headlands Technologies LLC3,037$7.01K0.00%+3,037New
Simplex Trading, LLC3,263$7.00K0.00%+3,263New
Caitong International Asset Management Co., Ltd2,147$4.96K0.00%+1,333+163.8%Added
Optiver Holding B.V.2,065$4.77K0.00%+1,260+156.5%Added
The PNC Financial Services Group, Inc.1,000$2.31K0.00%00.0%Unchanged
US Bancorp975$2.25K0.00%+44+4.7%Added
Clearstead Advisors, LLC690$1.59K0.00%+690New
Sterling Capital Management LLC408$9420.00%+243+147.3%Added
Essential Partners LLC327$7550.00%+327New
Parallel Advisors, LLC280$6470.00%00.0%Unchanged
Morton Brown Family Wealth, LLC260$6010.00%00.0%Unchanged
EverSource Wealth Advisors, LLC205$4730.00%−167−44.9%Reduced
Advisor Group Holdings, Inc.134$3110.00%00.0%Unchanged
Rothschild Investment LLC105$2430.00%+105New
SBI Securities Co., Ltd.80$1850.00%00.0%Unchanged
National Bank of Canada48$1100.00%+48New
True Wealth Design, LLC30$700.00%−102−77.3%Reduced
IFP Advisors, Inc14$320.00%+14New
Capital Advisors, Ltd. LLC79$00.00%00.0%Unchanged
Superstring Capital Management LP0$00.00%−755,599−100.0%Sold out
DAFNA Capital Management LLC0$00.00%−522,500−100.0%Sold out
HRT Financial LP0$00.00%−139,692−100.0%Sold out
BIT Capital GmbH0$00.00%−117,062−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−85,878−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−83,864−100.0%Sold out
Mariner, LLC0$00.00%−58,490−100.0%Sold out
Jain Global LLC0$00.00%−45,200−100.0%Sold out
Ameriprise Financial Inc0$00.00%−22,844−100.0%Sold out
HSBC Holdings PLC0$00.00%−20,257−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−13,071−100.0%Sold out
SIH Partners, LLLP0$00.00%−12,173−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−11,900−100.0%Sold out
Camelot Portfolios, LLC0$00.00%−11,000−100.0%Sold out
CIBC Private Wealth Group, LLC0$00.00%−6,833−100.0%Sold out
Allworth Financial LP0$00.00%−1,000−100.0%Sold out
Signaturefd, LLC0$00.00%−553−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−290−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−207−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−2−100.0%Sold out
Lindbrook Capital, LLC––––Not filed