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Taysha Gene Therapies, Inc.

TSHA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001806310

In the last 90 days, Taysha Gene Therapies, Inc. insiders filed 0 open-market purchases and 1 sale; 208 institutions reported holding it in 13F filings for Q2 2026, worth $2.03B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Taysha Gene Therapies, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
150
+24 vs. Q1 2025
Shares held
257.7M
+90.9M (+54.5%) vs. Q1 2025
Total value
$595.4M
+$363.4M (+156.7%) vs. Q1 2025
New holders
44
48 more added
Sold out
20
34 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TSHA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 150 institutions
Q1 2021: 46 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 65 institutionsQ1 2022: 71 institutionsQ2 2022: 59 institutionsQ3 2022: 54 institutionsQ4 2022: 52 institutionsQ1 2023: 44 institutionsQ2 2023: 39 institutionsQ3 2023: 63 institutionsQ4 2023: 87 institutionsQ1 2024: 109 institutionsQ2 2024: 107 institutionsQ3 2024: 119 institutionsQ4 2024: 131 institutionsQ1 2025: 127 institutionsQ2 2025: 150 institutionsQ3 2025: 155 institutionsQ4 2025: 195 institutionsQ1 2026: 191 institutionsQ2 2026: 208 institutions
Value heldQ2 2025: $595.4M
Q1 2021: $358.5MQ2 2021: $388.6MQ3 2021: $361.9MQ4 2021: $215.6MQ1 2022: $110.9MQ2 2022: $54.7MQ3 2022: $27.0MQ4 2022: $43.8MQ1 2023: $13.3MQ2 2023: $9.05MQ3 2023: $410.6MQ4 2023: $230.3MQ1 2024: $402.2MQ2 2024: $354.3MQ3 2024: $315.5MQ4 2024: $289.8MQ1 2025: $232.0MQ2 2025: $595.4MQ3 2025: $865.6MQ4 2025: $1.48BQ1 2026: $1.18BQ2 2026: $2.03B
Institutions holding TSHA and their total value by quarter
QuarterHoldersValue
Q2 2026208$2.03B
Q1 2026191$1.18B
Q4 2025195$1.48B
Q3 2025155$865.6M
Q2 2025150$595.4M
Q1 2025127$232.0M
Q4 2024131$289.8M
Q3 2024119$315.5M
Q2 2024107$354.3M
Q1 2024109$402.2M
Q4 202387$230.3M
Q3 202363$410.6M
Q2 202339$9.05M
Q1 202344$13.3M
Q4 202252$43.8M
Q3 202254$27.0M
Q2 202259$54.7M
Q1 202271$110.9M
Q4 202165$215.6M
Q3 202148$361.9M
Q2 202149$388.6M
Q1 202146$358.5M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Taysha Gene Therapies, Inc.; share changes are against Q1 2025.

Institutions holding TSHA in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Capital Advisors, Ltd. LLC79$00.00%00.0%Unchanged
IFP Advisors, Inc14$320.00%+14New
True Wealth Design, LLC30$700.00%−102−77.3%Reduced
National Bank of Canada48$1100.00%+48New
SBI Securities Co., Ltd.80$1850.00%00.0%Unchanged
Rothschild Investment LLC105$2430.00%+105New
Advisor Group Holdings, Inc.134$3110.00%00.0%Unchanged
EverSource Wealth Advisors, LLC205$4730.00%−167−44.9%Reduced
Morton Brown Family Wealth, LLC260$6010.00%00.0%Unchanged
Parallel Advisors, LLC280$6470.00%00.0%Unchanged
Essential Partners LLC327$7550.00%+327New
Sterling Capital Management LLC408$9420.00%+243+147.3%Added
Clearstead Advisors, LLC690$1.59K0.00%+690New
US Bancorp975$2.25K0.00%+44+4.7%Added
The PNC Financial Services Group, Inc.1,000$2.31K0.00%00.0%Unchanged
Optiver Holding B.V.2,065$4.77K0.00%+1,260+156.5%Added
Caitong International Asset Management Co., Ltd2,147$4.96K0.00%+1,333+163.8%Added
Simplex Trading, LLC3,263$7.00K0.00%+3,263New
Headlands Technologies LLC3,037$7.01K0.00%+3,037New
Raymond James Financial Inc3,605$8.33K0.00%+3,605New
Nisa Investment Advisors, LLC3,747$8.66K0.00%−483−11.4%Reduced
Point72 (DIFC) Ltd4,441$10.3K0.00%−11,087−71.4%Reduced
GF Fund Management Co. Ltd.5,248$12.1K0.00%00.0%Unchanged
St Germain D J Co Inc5,300$12.2K0.00%+5,300New
Amalgamated Bank5,534$13.0K0.00%00.0%Unchanged
Atticus Wealth Management, LLC7,425$17.2K0.00%00.0%Unchanged
Capital Investment Advisors, LLC10,000$23.1K0.00%00.0%Unchanged
Bordeaux Wealth Advisors LLC10,058$23.2K0.00%−51−0.5%Reduced
Ieq Capital, LLC10,063$23.2K0.00%+10,063New
Mirae Asset Global Investments Co., Ltd.10,103$23.3K0.00%+3,731+58.6%Added
Mackenzie Financial Corp11,214$25.9K0.00%+1,214+12.1%Added
Principal Financial Group Inc12,160$28.1K0.00%−1,829−13.1%Reduced
Marex Group plc12,500$28.9K0.00%00.0%Unchanged
California State Teachers Retirement System12,635$29.2K0.00%00.0%Unchanged
Xponance, Inc.12,837$29.7K0.00%+198+1.6%Added
CWM, LLC12,946$30.0K0.00%+2,419+23.0%Added
E Fund Management Co., Ltd.13,214$30.5K0.00%+13,214New
Howard Capital Management Inc.14,165$32.7K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.15,672$36.2K0.00%00.0%Unchanged
May Hill Capital, LLC16,051$37.1K0.01%+16,051New
Tower Research Capital LLC (TRC)17,606$40.7K0.00%+10,742+156.5%Added
Legal & General Group Plc18,395$42.5K0.00%−1,563−7.8%Reduced
BNP Paribas Arbitrage, SA18,591$42.9K0.00%+6,350+51.9%Added
Lee Financial Co20,000$46.2K0.01%00.0%Unchanged
CIBC World Markets Corp20,417$47.2K0.00%−18,480−47.5%Reduced
New York State Common Retirement Fund21,100$48.7K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System22,700$52.4K0.00%00.0%Unchanged
Prudential Financial Inc22,790$52.6K0.00%+7,650+50.5%Added
Cambridge Investment Research Advisors, Inc.23,690$55.0K0.00%+200+0.9%Added
Daiwa Securities Group Inc.23,841$55.0K0.00%+23,150+3,350.2%Added
Point72 Asia (Singapore) Pte. Ltd.25,252$58.3K0.01%+25,252New
Victory Capital Management Inc25,492$58.9K0.00%+6,475+34.0%Added
Profund Advisors LLC26,599$61.4K0.00%+26,599New
Leonteq Securities AG27,999$64.7K0.00%−52,000−65.0%Reduced
First Manhattan Co28,500$65.8K0.00%00.0%Unchanged
Ethic Inc.27,975$66.6K0.00%+27,975New
Two Sigma Investments, LP32,682$75.5K0.00%+32,682New
Virtus Investment Advisers, Inc.35,484$82.0K0.03%−37,473−51.4%Reduced
ProShare Advisors LLC43,746$101.1K0.00%−3,449−7.3%Reduced
Gsa Capital Partners LLP44,690$103.0K0.01%+44,690New
Williams & Novak, LLC45,000$104.0K0.09%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey45,678$105.5K0.00%00.0%Unchanged
Voya Investment Management LLC47,169$109.0K0.00%−1,447−3.0%Reduced
Creative Planning51,981$120.1K0.00%−26,354−33.6%Reduced
China Universal Asset Management Co., Ltd.52,527$121.3K0.01%+11,407+27.7%Added
Renaissance Technologies LLC54,900$126.8K0.00%+54,900New
Axq Capital, LP57,000$131.7K0.04%+57,000New
Commonwealth Equity Services, LLC60,036$139.0K0.00%−33−0.1%Reduced
Manufacturers Life Insurance Company, The61,005$140.9K0.00%−2,792−4.4%Reduced
Engineers Gate Manager LP64,617$149.3K0.00%+64,617New
Militia Capital Partners, LP66,800$154.3K0.07%+66,800New
EntryPoint Capital, LLC69,109$159.6K0.08%−66,788−49.1%Reduced
Omers Administration Corp72,900$168.4K0.00%+72,900New
Marshall Wace, LLP79,498$183.6K0.00%+79,498New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.80,571$186.1K0.00%+80,571New
Intech Investment Management LLC82,195$189.9K0.00%−17,717−17.7%Reduced
Price T Rowe Associates Inc84,603$196.0K0.00%+10,578+14.3%Added
Mirae Asset Global ETFs Holdings Ltd.96,543$223.4K0.00%−6,531−6.3%Reduced
Squarepoint Ops LLC100,226$231.5K0.00%+100,226New
Wells Fargo & Company107,234$247.7K0.00%−1,814−1.7%Reduced
Deutsche Bank AG107,716$248.8K0.00%−26,702−19.9%Reduced
MetLife Investment Management108,078$249.7K0.00%+367+0.3%Added
Franklin Resources Inc108,399$250.4K0.00%−7,839−6.7%Reduced
Los Angeles Capital Management LLC117,740$272.0K0.00%−25,070−17.6%Reduced
Rafferty Asset Management, LLC118,683$274.2K0.00%+118,683New
Citigroup Inc130,317$301.0K0.00%−2,877−2.2%Reduced
AQR Capital Management LLC135,766$313.6K0.00%+27,867+25.8%Added
Privium Fund Management B.V.134,900$315.7K0.07%00.0%Unchanged
Jane Street Group, LLC136,994$316.5K0.00%+136,994New
ExodusPoint Capital Management, LP148,357$343.0K0.00%+148,357New
Quadrature Capital Ltd161,940$373.3K0.01%+161,940New
Alliancebernstein L.P.179,620$414.9K0.00%+71,370+65.9%Added
Chicago Partners Investment Group LLC163,766$440.5K0.01%+47,201+40.5%Added
Affinity Asset Advisors, LLC200,000$462.0K0.07%+200,000New
Invesco Ltd.203,671$470.5K0.00%+43,772+27.4%Added
Susquehanna International Group, LLP212,572$491.0K0.00%−14,900−6.6%Reduced
JPMorgan Chase & Co222,649$514.3K0.00%−780,418−77.8%Reduced
Rhumbline Advisers233,256$538.8K0.00%+27,794+13.5%Added
UBS Group AG261,239$603.5K0.00%−156,893−37.5%Reduced
Kovitz Investment Group Partners, LLC298,667$689.9K0.00%+5,889+2.0%Added