Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2024
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 203
- +28 vs. Q3 2024
- Shares held
- 64.9M
- −2.70M (−4.0%) vs. Q3 2024
- Total value
- $3.63B
- +$92.1M (+2.6%) vs. Q3 2024
- New holders
- 52
- 66 more added
- Sold out
- 24
- 53 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Stifel Financial Corp | 19,516 | $1.09M | 0.00% | −326−1.6% | Reduced |
| Bryce Point Capital, LLC | 19,607 | $1.10M | 0.32% | +19,607 | New |
| Fiduciary Trust Co | 20,000 | $1.12M | 0.01% | 00.0% | Unchanged |
| Bellevue Group AG | 23,596 | $1.32M | 0.03% | +7,896+50.3% | Added |
| Crestline Management, LP | 25,062 | $1.40M | 0.05% | +6,064+31.9% | Added |
| Wellington Management Group LLP | 25,555 | $1.43M | 0.00% | −2,161−7.8% | Reduced |
| Corebridge Financial, Inc. | 27,220 | $1.52M | 0.01% | −2,054−7.0% | Reduced |
| Intech Investment Management LLC | 28,092 | $1.57M | 0.02% | +15,706+126.8% | Added |
| Harbor Capital Advisors, Inc. | 30,252 | $1.69M | 0.07% | −11,116−26.9% | Reduced |
| ADAR1 Capital Management, LLC | 30,941 | $1.73M | 0.36% | +30,941 | New |
| State of Wisconsin Investment Board | 32,262 | $1.81M | 0.00% | −191−0.6% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 33,156 | $1.86M | 0.00% | +654+2.0% | Added |
| MetLife Investment Management | 33,498 | $1.88M | 0.01% | +1,846+5.8% | Added |
| SEI Investments Co | 33,522 | $1.88M | 0.00% | +4,501+15.5% | Added |
| American Century Companies Inc | 33,766 | $1.89M | 0.00% | +33,766 | New |
| State of New Jersey Common Pension Fund D | 35,004 | $1.96M | 0.01% | +35,004 | New |
| Principal Financial Group Inc | 36,884 | $2.06M | 0.00% | +4,298+13.2% | Added |
| Wells Fargo & Company | 37,324 | $2.09M | 0.00% | +7,850+26.6% | Added |
| HighVista Strategies LLC | 37,426 | $2.10M | 0.78% | 00.0% | Unchanged |
| Citadel Advisors LLC | 40,419 | $2.26M | 0.00% | −62,359−60.7% | Reduced |
| Algert Global LLC | 41,551 | $2.33M | 0.05% | −12,620−23.3% | Reduced |
| California State Teachers Retirement System | 43,533 | $2.44M | 0.00% | −383−0.9% | Reduced |
| PDT Partners, LLC | 43,583 | $2.44M | 0.22% | +32,083+279.0% | Added |
| TD Asset Management Inc | 47,800 | $2.68M | 0.00% | +16,000+50.3% | Added |
| D. E. Shaw & Co., Inc. | 48,198 | $2.70M | 0.00% | +43,904+1,022.4% | Added |
| Wedge Capital Management L L P | 48,411 | $2.71M | 0.05% | −433−0.9% | Reduced |
| Deutsche Bank AG | 48,745 | $2.73M | 0.00% | +15,481+46.5% | Added |
| Nan Fung Group Holdings Ltd | 49,120 | $2.75M | 2.35% | 00.0% | Unchanged |
| Alps Advisors Inc | 49,700 | $2.78M | 0.02% | +49,700 | New |
| Artia Global Partners LP | 50,000 | $2.80M | 1.13% | +50,000 | New |
| Rafferty Asset Management, LLC | 50,394 | $2.82M | 0.01% | −14,182−22.0% | Reduced |
| Susquehanna International Group, LLP | 50,664 | $2.84M | 0.00% | +29,183+135.9% | Added |
| Legal & General Group Plc | 51,803 | $2.90M | 0.00% | +951+1.9% | Added |
| Ameriprise Financial Inc | 53,367 | $2.99M | 0.00% | +11,480+27.4% | Added |
| EAM Global Investors LLC | 56,936 | $3.19M | 0.57% | +56,936 | New |
| Jane Street Group, LLC | 58,415 | $3.27M | 0.01% | −50,771−46.5% | Reduced |
| Schonfeld Strategic Advisors LLC | 59,700 | $3.34M | 0.02% | +29,165+95.5% | Added |
| Manufacturers Life Insurance Company, The | 59,969 | $3.36M | 0.00% | +11,266+23.1% | Added |
| Alliancebernstein L.P. | 61,470 | $3.44M | 0.00% | +1,900+3.2% | Added |
| EAM Investors, LLC | 63,078 | $3.53M | 0.50% | +63,078 | New |
| Citigroup Inc | 69,777 | $3.91M | 0.00% | +28,580+69.4% | Added |
| Diadema Partners LP | 75,000 | $4.20M | 4.73% | +75,000 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 76,084 | $4.26M | 0.01% | +76,084 | New |
| Standard Life Aberdeen plc | 80,517 | $4.51M | 0.01% | −32,287−28.6% | Reduced |
| Rhumbline Advisers | 82,731 | $4.63M | 0.00% | +2,017+2.5% | Added |
| Cinctive Capital Management LP | 82,755 | $4.63M | 0.25% | +82,755 | New |
| BNP Paribas Arbitrage, SA | 85,249 | $4.77M | 0.00% | +70,824+491.0% | Added |
| Swiss National Bank | 90,200 | $5.05M | 0.00% | +900+1.0% | Added |
| Qube Research & Technologies Ltd | 95,235 | $5.33M | 0.01% | +95,235 | New |
| Voya Investment Management LLC | 97,169 | $5.44M | 0.01% | −5,663−5.5% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 99,447 | $5.57M | 0.25% | −1,514−1.5% | Reduced |
| Bank of America Corp | 104,488 | $5.85M | 0.00% | −1,762−1.7% | Reduced |
| Lazard Asset Management LLC | 106,261 | $5.95M | 0.01% | +106,261 | New |
| FMR LLC | 113,109 | $6.33M | 0.00% | +62,814+124.9% | Added |
| First Trust Advisors LP | 118,337 | $6.62M | 0.01% | +47,575+67.2% | Added |
| Barclays PLC | 135,397 | $7.58M | 0.00% | +29,000+27.3% | Added |
| Balyasny Asset Management LLC | 138,363 | $7.75M | 0.02% | +138,363 | New |
| Walleye Capital LLC | 144,342 | $8.08M | 0.08% | +144,342 | New |
| Nuveen Asset Management, LLC | 146,903 | $8.22M | 0.00% | −972−0.7% | Reduced |
| Bank of New York Mellon Corp | 148,246 | $8.30M | 0.00% | −680−0.5% | Reduced |
| Integral Health Asset Management, LLC | 150,000 | $8.40M | 0.74% | +150,000 | New |
| Lord, Abbett & Co. LLC | 160,651 | $8.99M | 0.03% | +58,005+56.5% | Added |
| Samsara BioCapital, LLC | 172,647 | $9.66M | 1.33% | 00.0% | Unchanged |
| Norges Bank | 205,649 | $11.5M | 0.00% | +139,373+210.3% | Added |
| StemPoint Capital LP | 208,016 | $11.6M | 2.92% | +166,748+404.1% | Added |
| UBS Asset Management Americas Inc | 218,544 | $12.2M | 0.00% | −6,829−3.0% | Reduced |
| UBS Group AG | 254,264 | $14.2M | 0.00% | +177,630+231.8% | Added |
| JPMorgan Chase & Co | 264,585 | $14.8M | 0.00% | +182,993+224.3% | Added |
| Franklin Resources Inc | 268,205 | $15.0M | 0.00% | +8,789+3.4% | Added |
| Silverarc Capital Management, LLC | 273,896 | $15.3M | 3.43% | +18,318+7.2% | Added |
| Invesco Ltd. | 302,846 | $17.0M | 0.00% | +38,429+14.5% | Added |
| Candriam Luxembourg S.C.A. | 332,392 | $18.6M | 0.11% | −62,985−15.9% | Reduced |
| Pictet Asset Management Holding SA | 375,349 | $21.0M | 0.02% | +46,010+14.0% | Added |
| Voloridge Investment Management, LLC | 380,537 | $21.3M | 0.08% | +27,214+7.7% | Added |
| Sofinnova Investments, Inc. | 397,428 | $22.2M | 1.63% | +120,750+43.6% | Added |
| OrbiMed Advisors LLC | 400,000 | $22.4M | 0.46% | −35,900−8.2% | Reduced |
| Cormorant Asset Management, LP | 400,000 | $22.4M | 1.23% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 440,250 | $24.6M | 0.00% | +6,384+1.5% | Added |
| Opaleye Management Inc. | 500,000 | $28.0M | 4.90% | 00.0% | Unchanged |
| Northern Trust Corp | 545,314 | $30.5M | 0.00% | +46,848+9.4% | Added |
| Morgan Stanley | 560,087 | $31.4M | 0.00% | +95,483+20.6% | Added |
| Loomis Sayles & Co L P | 618,485 | $34.6M | 0.04% | −18,143−2.8% | Reduced |
| Hood River Capital Management LLC | 643,691 | $36.0M | 0.53% | +29,093+4.7% | Added |
| Price T Rowe Associates Inc | 685,152 | $38.4M | 0.00% | +134,622+24.5% | Added |
| Marshall Wace, LLP | 692,803 | $38.8M | 0.05% | +286,188+70.4% | Added |
| Checkpoint Capital L.P. | 727,982 | $40.8M | 20.74% | +64,601+9.7% | Added |
| Rock Springs Capital Management LP | 1,162,718 | $65.1M | 2.48% | −65,375−5.3% | Reduced |
| Alkeon Capital Management LLC | 1,167,700 | $65.4M | 0.38% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 1,219,554 | $68.3M | 0.03% | +621,432+103.9% | Added |
| Geode Capital Management, LLC | 1,255,799 | $70.3M | 0.01% | −3890.0% | Reduced |
| Driehaus Capital Management LLC | 1,290,975 | $72.3M | 0.60% | −8,515−0.7% | Reduced |
| Polar Capital Holdings Plc | 1,500,000 | $84.0M | 0.47% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 1,549,635 | $86.7M | 0.19% | −114,265−6.9% | Reduced |
| Goldman Sachs Group Inc | 1,812,206 | $101.4M | 0.02% | −2,067,590−53.3% | Reduced |
| State Street Corp | 1,840,870 | $103.1M | 0.00% | −152,296−7.6% | Reduced |
| Frazier Life Sciences Management, L.P. | 1,869,808 | $104.7M | 4.34% | −547,144−22.6% | Reduced |
| NEA Management Company, LLC | 2,909,956 | $162.9M | 9.19% | 00.0% | Unchanged |
| Vanguard Group Inc | 3,442,600 | $192.7M | 0.00% | −5,311−0.2% | Reduced |
| Perceptive Advisors LLC | 3,680,473 | $206.0M | 5.74% | +120,259+3.4% | Added |
| Baker Bros. Advisors LP | 6,084,249 | $340.6M | 3.64% | −314,117−4.9% | Reduced |