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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Prime Medicine, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
187
−1 vs. Q1 2026
Shares held
106.6M
+8.18M (+8.3%) vs. Q1 2026
Total value
$393.5M
+$51.3M (+15.0%) vs. Q1 2026
New holders
22
64 more added
Sold out
23
67 more reduced

4 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 187 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 66 institutionsQ1 2023: 76 institutionsQ2 2023: 79 institutionsQ3 2023: 83 institutionsQ4 2023: 105 institutionsQ1 2024: 115 institutionsQ2 2024: 122 institutionsQ3 2024: 116 institutionsQ4 2024: 132 institutionsQ1 2025: 125 institutionsQ2 2025: 121 institutionsQ3 2025: 167 institutionsQ4 2025: 183 institutionsQ1 2026: 192 institutionsQ2 2026: 187 institutions
Value heldQ2 2026: $393.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $767.8MQ1 2023: $512.1MQ2 2023: $675.7MQ3 2023: $472.3MQ4 2023: $431.4MQ1 2024: $466.6MQ2 2024: $354.0MQ3 2024: $265.9MQ4 2024: $188.0MQ1 2025: $120.4MQ2 2025: $145.0MQ3 2025: $511.5MQ4 2025: $336.5MQ1 2026: $342.6MQ2 2026: $393.5M
Institutions holding PRME and their total value by quarter
QuarterHoldersValue
Q2 2026187$393.5M
Q1 2026192$342.6M
Q4 2025183$336.5M
Q3 2025167$511.5M
Q2 2025121$145.0M
Q1 2025125$120.4M
Q4 2024132$188.0M
Q3 2024116$265.9M
Q2 2024122$354.0M
Q1 2024115$466.6M
Q4 2023105$431.4M
Q3 202383$472.3M
Q2 202379$675.7M
Q1 202376$512.1M
Q4 202266$767.8M
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2026.

Institutions holding PRME in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Polymer Capital Management (US) LLC0$00.00%−10,317−100.0%Sold out
MTM Investment Management, LLC0$00.00%−3,090−100.0%Sold out
Scarborough Advisors, LLC0$00.00%−1,258−100.0%Sold out
MAI Capital Management0$00.00%−386−100.0%Sold out
Vanguard National Trust Co0$00.00%−334−100.0%Sold out
True Wealth Design, LLC0$00.00%−152−100.0%Sold out
Keating Financial Advisory Services, Inc.0$00.00%−59−100.0%Sold out
US Bancorp0$00.00%−33−100.0%Sold out
SJS Investment Consulting Inc.0$00.00%−10−100.0%Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−3−100.0%Sold out
Janus Henderson Group PLC––––Not filed
CWM, LLC––––Not filed
Financial Connections Group, Inc.––––Not filed
Sunbelt Securities, Inc.––––Not filed