Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Prime Medicine, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 192
- +14 vs. Q4 2025
- Shares held
- 98.6M
- +9.86M (+11.1%) vs. Q4 2025
- Total value
- $342.6M
- +$34.8M (+11.3%) vs. Q4 2025
- New holders
- 39
- 74 more added
- Sold out
- 25
- 49 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 31 | $0 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 2 | $7 | 0.00% | −8−80.0% | Reduced |
| Twin Peaks Wealth Advisors, LLC | 3 | $10 | 0.00% | +3 | New |
| National Bank of Canada | 10 | $35 | 0.00% | +10 | New |
| SJS Investment Consulting Inc. | 10 | $35 | 0.00% | +10 | New |
| US Bancorp | 33 | $115 | 0.00% | +33 | New |
| Newbridge Financial Services Group, Inc. | 45 | $157 | 0.00% | +45 | New |
| Keating Financial Advisory Services, Inc. | 59 | $205 | 0.00% | +59 | New |
| Harbour Investments, Inc. | 74 | $258 | 0.00% | +74 | New |
| Sunbelt Securities, Inc. | 80 | $278 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 154 | $522 | 0.00% | +83+116.9% | Added |
| True Wealth Design, LLC | 152 | $529 | 0.00% | +37+32.2% | Added |
| SRS Capital Advisors, Inc. | 230 | $800 | 0.00% | +230 | New |
| Parkside Financial Bank & Trust | 285 | $992 | 0.00% | 00.0% | Unchanged |
| Basecamp Wealth Advisors LLC | 287 | $999 | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 319 | $1.11K | 0.00% | 00.0% | Unchanged |
| Vanguard National Trust Co | 334 | $1.16K | 0.00% | +334 | New |
| Rothschild Investment LLC | 382 | $1.33K | 0.00% | +37+10.7% | Added |
| Caitong International Asset Management Co., Ltd | 383 | $1.33K | 0.00% | −38,313−99.0% | Reduced |
| MAI Capital Management | 386 | $1.34K | 0.00% | +112+40.9% | Added |
| SBI Securities Co., Ltd. | 391 | $1.36K | 0.00% | +88+29.0% | Added |
| Fortitude Family Office, LLC | 436 | $1.52K | 0.00% | +140+47.3% | Added |
| Fairman Group, LLC | 500 | $1.74K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 647 | $2.25K | 0.00% | +536+482.9% | Added |
| Optiver Holding B.V. | 892 | $3.10K | 0.00% | +732+457.5% | Added |
| GWM Advisors LLC | 1,000 | $3.48K | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 1,008 | $3.51K | 0.00% | +787+356.1% | Added |
| Scarborough Advisors, LLC | 1,258 | $4.38K | 0.00% | +1+0.1% | Added |
| EverSource Wealth Advisors, LLC | 2,000 | $6.96K | 0.00% | +238+13.5% | Added |
| CI Private Wealth, LLC | 41,221 | $8.64K | 0.00% | +2,444+6.3% | Added |
| Owl Creek Wealth Partners LLC | 2,615 | $9.10K | 0.00% | +2,615 | New |
| MTM Investment Management, LLC | 3,090 | $10.8K | 0.00% | 00.0% | Unchanged |
| Financial Connections Group, Inc. | 3,712 | $12.0K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 3,462 | $12.0K | 0.00% | −2,274−39.6% | Reduced |
| GF Fund Management Co. Ltd. | 4,036 | $14.0K | 0.00% | +489+13.8% | Added |
| Advisor Group Holdings, Inc. | 4,097 | $14.3K | 0.00% | −4,331−51.4% | Reduced |
| Allworth Financial LP | 4,405 | $15.3K | 0.00% | +1,290+41.4% | Added |
| NBC Securities, Inc. | 5,000 | $17.4K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 5,000 | $17.4K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 8,407 | $29.3K | 0.00% | +2,506+42.5% | Added |
| New York State Common Retirement Fund | 8,434 | $29.4K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 9,254 | $32.0K | 0.00% | +4,365+89.3% | Added |
| Nisa Investment Advisors, LLC | 9,346 | $32.5K | 0.00% | +4,800+105.6% | Added |
| Mirae Asset Global Investments Co., Ltd. | 9,415 | $32.8K | 0.00% | +643+7.3% | Added |
| Federation des caisses Desjardins du Quebec | 9,500 | $33.1K | 0.00% | −2,500−20.8% | Reduced |
| Forum Financial Management, LP | 10,000 | $34.8K | 0.00% | 00.0% | Unchanged |
| Glen Eagle Advisors, LLC | 10,000 | $34.8K | 0.00% | 00.0% | Unchanged |
| Polymer Capital Management (US) LLC | 10,317 | $35.9K | 0.01% | −25,664−71.3% | Reduced |
| Wealthfront Advisers LLC | 10,379 | $36.1K | 0.00% | +10,379 | New |
| Victory Capital Management Inc | 10,817 | $37.6K | 0.00% | +16+0.1% | Added |
| Teacher Retirement System of Texas | 11,058 | $38.5K | 0.00% | −1,177−9.6% | Reduced |
| Sequoia Financial Advisors, LLC | 11,673 | $40.6K | 0.00% | +11,673 | New |
| Raymond James Financial Inc | 12,044 | $41.9K | 0.00% | −15,000−55.5% | Reduced |
| Pictet Asset Management Holding SA | 12,107 | $42.1K | 0.00% | +12,107 | New |
| Mercer Global Advisors Inc | 12,305 | $42.8K | 0.00% | +12,305 | New |
| Cambridge Investment Research Advisors, Inc. | 12,337 | $43.0K | 0.00% | +12,337 | New |
| Prime Capital Investment Advisors, LLC | 12,945 | $45.0K | 0.00% | −1,110−7.9% | Reduced |
| JTC Employer Solutions Trusteee Ltd | 13,249 | $46.0K | 0.00% | 00.0% | Unchanged |
| Sterling Investment Advisors, Ltd. | 13,400 | $46.6K | 0.01% | 00.0% | Unchanged |
| Benjamin Edwards Inc | 13,852 | $48.2K | 0.00% | +13,852 | New |
| Sanctuary Advisors, LLC | 13,894 | $48.4K | 0.00% | −765−5.2% | Reduced |
| Prudential Financial Inc | 14,755 | $51.3K | 0.00% | +14,755 | New |
| Martingale Asset Management L P | 14,848 | $51.7K | 0.00% | +40+0.3% | Added |
| Levin Capital Strategies, L.P. | 15,000 | $52.2K | 0.00% | 00.0% | Unchanged |
| Magnetar Financial LLC | 15,784 | $54.9K | 0.00% | +15,784 | New |
| Graham Capital Management, L.P. | 16,015 | $55.7K | 0.00% | −98,665−86.0% | Reduced |
| Commonwealth Equity Services, LLC | 16,437 | $57.2K | 0.00% | −17,962−52.2% | Reduced |
| Thompson Davis & Co., Inc. | 17,240 | $60.0K | 0.04% | −5,500−24.2% | Reduced |
| Voya Investment Management LLC | 17,345 | $60.4K | 0.00% | −146−0.8% | Reduced |
| Scientech Research LLC | 17,931 | $62.4K | 0.05% | −4,462−19.9% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,225 | $63.4K | 0.00% | +9,411+106.8% | Added |
| KLP Kapitalforvaltning AS | 18,500 | $64.4K | 0.00% | 00.0% | Unchanged |
| Shelton Wealth Management, LLC | 20,066 | $69.8K | 0.03% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 21,814 | $75.9K | 0.00% | +21,007+2,603.1% | Added |
| JustInvest LLC | 21,954 | $76.4K | 0.00% | −1,697−7.2% | Reduced |
| ProShare Advisors LLC | 22,968 | $79.9K | 0.00% | −3,190−12.2% | Reduced |
| Group One Trading, L.P. | 24,766 | $86.2K | 0.00% | −78,447−76.0% | Reduced |
| Arizona State Retirement System | 24,791 | $86.3K | 0.00% | +706+2.9% | Added |
| Nomura Holdings Inc | 24,823 | $86.4K | 0.00% | +34+0.1% | Added |
| Turtle Creek Wealth Advisors, LLC | 25,000 | $87.0K | 0.01% | +25,000 | New |
| Abacus Planning Group, Inc. | 25,188 | $87.7K | 0.01% | 00.0% | Unchanged |
| Vanguard Investments Australia, Ltd. | 26,124 | $90.9K | 0.00% | +26,124 | New |
| Blue Bell Private Wealth Management, LLC | 27,015 | $94.0K | 0.01% | +27,015 | New |
| E Fund Management Co., Ltd. | 27,099 | $94.3K | 0.00% | +27,099 | New |
| Creative Planning | 28,246 | $98.3K | 0.00% | +10,354+57.9% | Added |
| Manufacturers Life Insurance Company, The | 28,872 | $100.5K | 0.00% | −2,730−8.6% | Reduced |
| Envestnet Asset Management Inc | 29,040 | $101.1K | 0.00% | −3,536−10.9% | Reduced |
| SEI Investments Co | 29,183 | $101.6K | 0.00% | +29,183 | New |
| Transcend Wealth Collective, LLC | 30,070 | $104.6K | 0.01% | +3,570+13.5% | Added |
| Intech Investment Management LLC | 30,538 | $106.3K | 0.00% | −4,498−12.8% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 30,751 | $107.0K | 0.00% | +9,585+45.3% | Added |
| State of New Jersey Common Pension Fund D | 30,845 | $107.3K | 0.00% | +30,845 | New |
| China Universal Asset Management Co., Ltd. | 32,033 | $111.5K | 0.01% | +2,619+8.9% | Added |
| Crestwood Advisors Group LLC | 32,374 | $112.7K | 0.00% | +401+1.3% | Added |
| Oppenheimer & Co Inc | 33,656 | $117.1K | 0.00% | +21,223+170.7% | Added |
| CWM, LLC | 33,811 | $117.7K | 0.00% | +8,384+33.0% | Added |
| BNP Paribas Arbitrage, SA | 34,413 | $119.8K | 0.00% | +24,590+250.3% | Added |
| Kingsview Wealth Management, LLC | 35,000 | $121.8K | 0.00% | +20,000+133.3% | Added |
| Wealth Enhancement Advisory Services, LLC | 37,681 | $125.1K | 0.00% | +11,583+44.4% | Added |
| Axq Capital, LP | 36,742 | $127.9K | 0.02% | +3,337+10.0% | Added |