Skip to main content

Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

Q1 2026 vs. Q4 2025

How the institutions holding Prime Medicine, Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026All holders in Q4 2025

13F holders of PRME: Q4 2025 compared with Q1 2026
MeasureQ4 2025Of which not filed for Q1 2026Q1 2026Change
Holders1835192+14
Shares97.0M8.28M98.6M+9.86M (+11.1%)
Value$336.5M$28.7M$342.6M+$34.8M (+11.3%)

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (39)

Institutions that held Prime Medicine, Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to PRME in Q1 2026
InstitutionSharesValue% of portfolio
Vanguard Capital Management LLC4,474,162$15.6M0.00%
ADAR1 Capital Management, LLC1,973,282$6.87M0.41%
Redmile Group, LLC1,590,832$5.54M0.37%
Vanguard Portfolio Management LLC862,204$3.00M0.00%
Vanguard Fiduciary Trust Co717,002$2.50M0.00%
Alessandra Capital Management, LLC425,510$1.48M1.26%
Marshall Wace, LLP141,957$494.0K0.00%
Concurrent Investment Advisors, LLC74,177$258.1K0.00%
Tudor Investment Corp Et Al61,546$214.2K0.00%
Vanguard Asset Management, Ltd59,021$205.4K0.00%
Aquatic Capital Management LLC54,230$188.7K0.01%
Los Angeles Capital Management LLC52,615$183.1K0.00%
Vanguard Global Advisers, LLC44,269$154.1K0.00%
VARCOV Co.41,964$146.0K0.05%
DRW Securities, LLC40,964$142.6K0.01%
State of New Jersey Common Pension Fund D30,845$107.3K0.00%
SEI Investments Co29,183$101.6K0.00%
E Fund Management Co., Ltd.27,099$94.3K0.00%
Blue Bell Private Wealth Management, LLC27,015$94.0K0.01%
Vanguard Investments Australia, Ltd.26,124$90.9K0.00%
Turtle Creek Wealth Advisors, LLC25,000$87.0K0.01%
Magnetar Financial LLC15,784$54.9K0.00%
Prudential Financial Inc14,755$51.3K0.00%
Benjamin Edwards Inc13,852$48.2K0.00%
Cambridge Investment Research Advisors, Inc.12,337$43.0K0.00%
Mercer Global Advisors Inc12,305$42.8K0.00%
Pictet Asset Management Holding SA12,107$42.1K0.00%
Sequoia Financial Advisors, LLC11,673$40.6K0.00%
Wealthfront Advisers LLC10,379$36.1K0.00%
Owl Creek Wealth Partners LLC2,615$9.10K0.00%
Vanguard National Trust Co334$1.16K0.00%
SRS Capital Advisors, Inc.230$8000.00%
Harbour Investments, Inc.74$2580.00%
Keating Financial Advisory Services, Inc.59$2050.00%
Newbridge Financial Services Group, Inc.45$1570.00%
US Bancorp33$1150.00%
National Bank of Canada10$350.00%
SJS Investment Consulting Inc.10$350.00%
Twin Peaks Wealth Advisors, LLC3$100.00%

Sold out (25)

Institutions that held Prime Medicine, Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Not filed for Q1 2026 yet (5)

Institutions that held Prime Medicine, Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding PRME in Q4 2025 that haven't filed for Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Vanguard Group Inc6,467,872$22.4M
MWG Caph Ltd1,792,210$6.22M
Clarius Group, LLC16,080$55.8K
CIBC Private Wealth Group, LLC267$926
Global Retirement Partners, LLC146$507