Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2025
Institutional positions in Prime Medicine, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 121
- −4 vs. Q1 2025
- Shares held
- 58.7M
- −1.70M (−2.8%) vs. Q1 2025
- Total value
- $145.0M
- +$24.6M (+20.4%) vs. Q1 2025
- New holders
- 29
- 36 more added
- Sold out
- 33
- 35 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Moore Capital Management, LP | 500,000 | $1.24M | 0.02% | 00.0% | Unchanged |
| Northern Trust Corp | 512,234 | $1.27M | 0.00% | −15,075−2.9% | Reduced |
| Charles Schwab Investment Management Inc | 518,628 | $1.28M | 0.00% | +14,931+3.0% | Added |
| Citadel Advisors LLC | 521,508 | $1.29M | 0.00% | +521,508 | New |
| Morgan Stanley | 587,676 | $1.45M | 0.00% | +232,500+65.5% | Added |
| Farallon Capital Management, L.L.C. | 750,000 | $1.85M | 0.01% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 818,518 | $2.02M | 0.02% | +818,518 | New |
| Greenwich Wealth Management LLC | 846,201 | $2.09M | 0.10% | +27,200+3.3% | Added |
| State Street Corp | 1,239,337 | $3.06M | 0.00% | +94,032+8.2% | Added |
| Geode Capital Management, LLC | 1,510,749 | $3.73M | 0.00% | −15,781−1.0% | Reduced |
| Casdin Capital, LLC | 1,567,175 | $3.87M | 0.35% | +1,200,000+326.8% | Added |
| Nikko Asset Management Americas, Inc. | 1,589,117 | $3.89M | 0.04% | −1,336,906−45.7% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 1,594,518 | $3.94M | 0.00% | −1,331,505−45.5% | Reduced |
| MWG Management Limited | 1,792,210 | $4.43M | 8.53% | 00.0% | Unchanged |
| Redmile Group, LLC | 2,074,350 | $5.12M | 0.55% | 00.0% | Unchanged |
| ARK Investment Management LLCSuperinvestorARK Invest | 2,322,669 | $5.74M | 0.04% | −772,503−25.0% | Reduced |
| Vanguard Group Inc | 3,627,510 | $8.96M | 0.00% | −13,838−0.4% | Reduced |
| FMR LLC | 3,744,427 | $9.25M | 0.00% | −2,808−0.1% | Reduced |
| BlackRock, Inc. | 4,485,828 | $11.1M | 0.00% | +179,617+4.2% | Added |
| T. Rowe Price Investment Management, Inc. | 6,484,787 | $16.0M | 0.01% | +2,341,691+56.5% | Added |
| Alphabet Inc. | 15,062,498 | $37.2M | 1.74% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 0 | $0 | 0.00% | −1,028,466−100.0% | Sold out |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −700,000−100.0% | Sold out |
| Samsara BioCapital, LLC | 0 | $0 | 0.00% | −405,228−100.0% | Sold out |
| Gsa Capital Partners LLP | 0 | $0 | 0.00% | −153,273−100.0% | Sold out |
| Vestmark Advisory Solutions, Inc. | 0 | $0 | 0.00% | −78,599−100.0% | Sold out |
| Tudor Investment Corp Et Al | 0 | $0 | 0.00% | −60,368−100.0% | Sold out |
| Virtus Investment Advisers, Inc. | 0 | $0 | 0.00% | −54,535−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −53,900−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −50,514−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −39,967−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −38,255−100.0% | Sold out |
| Cerity Partners LLC | 0 | $0 | 0.00% | −31,387−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −28,478−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −27,785−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −24,802−100.0% | Sold out |
| Sanctuary Advisors, LLC | 0 | $0 | 0.00% | −23,822−100.0% | Sold out |
| Envestnet Asset Management Inc | 0 | $0 | 0.00% | −23,515−100.0% | Sold out |
| Avanza Fonder AB | 0 | $0 | 0.00% | −23,918−100.0% | Sold out |
| Benjamin Edwards Inc | 0 | $0 | 0.00% | −21,101−100.0% | Sold out |
| CIBC World Markets Corp | 0 | $0 | 0.00% | −12,585−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −11,426−100.0% | Sold out |
| Pathstone Holdings, LLC | 0 | $0 | 0.00% | −11,250−100.0% | Sold out |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −4,110−100.0% | Sold out |
| Quadrant Capital Group LLC | 0 | $0 | 0.00% | −1,842−100.0% | Sold out |
| First Horizon Advisors, Inc. | 0 | $0 | 0.00% | −932−100.0% | Sold out |
| Rise Advisors, LLC | 0 | $0 | 0.00% | −575−100.0% | Sold out |
| Prestige Wealth Management Group LLC | 0 | $0 | 0.00% | −434−100.0% | Sold out |
| Hughes Financial Services, LLC | 0 | $0 | 0.00% | −480−100.0% | Sold out |
| Comerica Bank | 0 | $0 | 0.00% | −315−100.0% | Sold out |
| Coldstream Capital Management Inc | 0 | $0 | 0.00% | −283−100.0% | Sold out |
| Parallel Advisors, LLC | 0 | $0 | 0.00% | −110−100.0% | Sold out |
| Cordant, Inc. | 0 | $0 | 0.00% | −33−100.0% | Sold out |
| Avion Wealth | 0 | $0 | 0.00% | −178−100.0% | Sold out |