Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Prime Medicine, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 125
- −6 vs. Q4 2024
- Shares held
- 60.4M
- −3.56M (−5.6%) vs. Q4 2024
- Total value
- $120.4M
- −$66.4M (−35.6%) vs. Q4 2024
- New holders
- 23
- 41 more added
- Sold out
- 29
- 35 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| EverSource Wealth Advisors, LLC | 1,012 | $2.01K | 0.00% | +1,006+16,766.7% | Added |
| First Horizon Advisors, Inc. | 932 | $1.85K | 0.00% | −177−16.0% | Reduced |
| Leonteq Securities AG | 915 | $1.82K | 0.00% | +915 | New |
| Fairman Group, LLC | 500 | $1.46K | 0.00% | 00.0% | Unchanged |
| Rise Advisors, LLC | 575 | $1.14K | 0.00% | +575 | New |
| SBI Securities Co., Ltd. | 574 | $1.14K | 0.00% | −631−52.4% | Reduced |
| Daiwa Securities Group Inc. | 398 | $1.00K | 0.00% | 00.0% | Unchanged |
| Prestige Wealth Management Group LLC | 434 | $864 | 0.00% | +434 | New |
| Hughes Financial Services, LLC | 480 | $857 | 0.00% | +480 | New |
| Principal Securities, Inc. | 280 | $818 | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 324 | $645 | 0.00% | +178+121.9% | Added |
| Comerica Bank | 315 | $628 | 0.00% | −758−70.6% | Reduced |
| Nisa Investment Advisors, LLC | 315 | $627 | 0.00% | −12,301−97.5% | Reduced |
| Rothschild Investment LLC | 315 | $627 | 0.00% | +35+12.5% | Added |
| Coldstream Capital Management Inc | 283 | $564 | 0.00% | +283 | New |
| Larson Financial Group LLC | 200 | $398 | 0.00% | +200 | New |
| Advisor Group Holdings, Inc. | 164 | $324 | 0.00% | −224−57.7% | Reduced |
| Parallel Advisors, LLC | 110 | $219 | 0.00% | +110 | New |
| Sterling Capital Management LLC | 58 | $115 | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 52 | $103 | 0.00% | −336−86.6% | Reduced |
| True Wealth Design, LLC | 50 | $100 | 0.00% | +50 | New |
| Cordant, Inc. | 33 | $66 | 0.00% | +33 | New |
| IFP Advisors, Inc | 24 | $48 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 33 | $0 | 0.00% | +19+135.7% | Added |
| Avion Wealth | 178 | $0 | 0.00% | +178 | New |
| Westwood Holdings Group Inc. | 0 | $0 | 0.00% | −883,129−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −403,739−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −144,719−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −131,732−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −101,758−100.0% | Sold out |
| Aristides Capital LLC | 0 | $0 | 0.00% | −70,500−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −68,528−100.0% | Sold out |
| Sculptor Capital LP | 0 | $0 | 0.00% | −50,700−100.0% | Sold out |
| PEAK6 LLC | 0 | $0 | 0.00% | −30,013−100.0% | Sold out |
| Creative Planning | 0 | $0 | 0.00% | −27,623−100.0% | Sold out |
| MetLife Investment Management | 0 | $0 | 0.00% | −25,031−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −23,618−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −21,695−100.0% | Sold out |
| Sherbrooke Park Advisers LLC | 0 | $0 | 0.00% | −20,441−100.0% | Sold out |
| Impact Partnership Wealth, LLC | 0 | $0 | 0.00% | −17,274−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −16,342−100.0% | Sold out |
| Axq Capital, LP | 0 | $0 | 0.00% | −15,363−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −14,466−100.0% | Sold out |
| Oppenheimer & Co Inc | 0 | $0 | 0.00% | −12,106−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −2,230−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −309−100.0% | Sold out |
| Raffa Wealth Management, LLC | 0 | $0 | 0.00% | −250−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −202−100.0% | Sold out |
| Allworth Financial LP | 0 | $0 | 0.00% | −141−100.0% | Sold out |
| Massmutual Trust Co FSB | 0 | $0 | 0.00% | −104−100.0% | Sold out |
| Catherine Avery Investment Management LLC | 0 | $0 | 0.00% | −67−100.0% | Sold out |
| Federated Hermes, Inc. | 0 | $0 | 0.00% | −6−100.0% | Sold out |
| Lazard Asset Management LLC | 0 | $0 | 0.00% | −26−100.0% | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |