Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2025
Institutional positions in Prime Medicine, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 125
- −6 vs. Q4 2024
- Shares held
- 60.4M
- −3.56M (−5.6%) vs. Q4 2024
- Total value
- $120.4M
- −$66.4M (−35.6%) vs. Q4 2024
- New holders
- 23
- 41 more added
- Sold out
- 29
- 35 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 33 | $0 | 0.00% | +19+135.7% | Added |
| Avion Wealth | 178 | $0 | 0.00% | +178 | New |
| IFP Advisors, Inc | 24 | $48 | 0.00% | 00.0% | Unchanged |
| Cordant, Inc. | 33 | $66 | 0.00% | +33 | New |
| True Wealth Design, LLC | 50 | $100 | 0.00% | +50 | New |
| Russell Investments Group, Ltd. | 52 | $103 | 0.00% | −336−86.6% | Reduced |
| Sterling Capital Management LLC | 58 | $115 | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 110 | $219 | 0.00% | +110 | New |
| Advisor Group Holdings, Inc. | 164 | $324 | 0.00% | −224−57.7% | Reduced |
| Larson Financial Group LLC | 200 | $398 | 0.00% | +200 | New |
| Coldstream Capital Management Inc | 283 | $564 | 0.00% | +283 | New |
| Nisa Investment Advisors, LLC | 315 | $627 | 0.00% | −12,301−97.5% | Reduced |
| Rothschild Investment LLC | 315 | $627 | 0.00% | +35+12.5% | Added |
| Comerica Bank | 315 | $628 | 0.00% | −758−70.6% | Reduced |
| The PNC Financial Services Group, Inc. | 324 | $645 | 0.00% | +178+121.9% | Added |
| Principal Securities, Inc. | 280 | $818 | 0.00% | 00.0% | Unchanged |
| Hughes Financial Services, LLC | 480 | $857 | 0.00% | +480 | New |
| Prestige Wealth Management Group LLC | 434 | $864 | 0.00% | +434 | New |
| Daiwa Securities Group Inc. | 398 | $1.00K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 574 | $1.14K | 0.00% | −631−52.4% | Reduced |
| Rise Advisors, LLC | 575 | $1.14K | 0.00% | +575 | New |
| Fairman Group, LLC | 500 | $1.46K | 0.00% | 00.0% | Unchanged |
| Leonteq Securities AG | 915 | $1.82K | 0.00% | +915 | New |
| First Horizon Advisors, Inc. | 932 | $1.85K | 0.00% | −177−16.0% | Reduced |
| EverSource Wealth Advisors, LLC | 1,012 | $2.01K | 0.00% | +1,006+16,766.7% | Added |
| Royal Bank of Canada | 1,640 | $3.00K | 0.00% | +478+41.1% | Added |
| Quadrant Capital Group LLC | 1,842 | $3.67K | 0.00% | +1,009+121.1% | Added |
| Amalgamated Bank | 1,957 | $4.00K | 0.00% | +610+45.3% | Added |
| Signaturefd, LLC | 2,649 | $5.27K | 0.00% | +996+60.3% | Added |
| GF Fund Management Co. Ltd. | 3,358 | $6.68K | 0.00% | +658+24.4% | Added |
| Ameritas Investment Partners, Inc. | 3,901 | $7.76K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 4,110 | $8.18K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 4,389 | $8.73K | 0.00% | +18+0.4% | Added |
| Legal & General Group Plc | 5,915 | $11.8K | 0.00% | −364−5.8% | Reduced |
| Simplex Trading, LLC | 8,376 | $16.0K | 0.00% | +6,918+474.5% | Added |
| New York State Common Retirement Fund | 8,434 | $16.8K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 10,763 | $19.2K | 0.00% | +10,737+41,296.2% | Added |
| Tower Research Capital LLC (TRC) | 9,909 | $19.7K | 0.00% | +8,512+609.3% | Added |
| Pathstone Holdings, LLC | 11,250 | $22.4K | 0.00% | −61−0.5% | Reduced |
| State Board of Administration of Florida Retirement System | 11,420 | $22.7K | 0.00% | 00.0% | Unchanged |
| American Century Companies Inc | 11,426 | $22.7K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Advisory Services, LLC | 12,230 | $24.3K | 0.00% | +12,230 | New |
| CIBC World Markets Corp | 12,585 | $25.0K | 0.00% | +12,585 | New |
| Invesco Ltd. | 14,836 | $29.5K | 0.00% | −235−1.6% | Reduced |
| JustInvest LLC | 15,237 | $30.3K | 0.00% | +2,859+23.1% | Added |
| Clarius Group, LLC | 16,080 | $32.0K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 17,015 | $33.9K | 0.00% | −2,008−10.6% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 17,092 | $34.0K | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 17,222 | $34.3K | 0.00% | −951−5.2% | Reduced |
| ProShare Advisors LLC | 18,194 | $36.2K | 0.00% | −3,992−18.0% | Reduced |
| CWM, LLC | 20,466 | $41.0K | 0.00% | +18,034+741.5% | Added |
| Benjamin Edwards Inc | 21,101 | $42.0K | 0.00% | −820−3.7% | Reduced |
| Avanza Fonder AB | 23,918 | $42.8K | 0.00% | +1,438+6.4% | Added |
| HighTower Advisors, LLC | 21,646 | $43.1K | 0.00% | +56+0.3% | Added |
| Envestnet Asset Management Inc | 23,515 | $46.8K | 0.00% | +1,958+9.1% | Added |
| Sanctuary Advisors, LLC | 23,822 | $47.4K | 0.00% | +23,822 | New |
| Prime Capital Investment Advisors, LLC | 24,261 | $48.3K | 0.00% | +306+1.3% | Added |
| Manufacturers Life Insurance Company, The | 24,924 | $49.6K | 0.00% | +1,332+5.6% | Added |
| Quadrature Capital Ltd | 24,802 | $49.6K | 0.00% | +24,802 | New |
| China Universal Asset Management Co., Ltd. | 26,309 | $52.4K | 0.00% | −1,502−5.4% | Reduced |
| Corebridge Financial, Inc. | 27,785 | $55.3K | 0.00% | −412−1.5% | Reduced |
| Brevan Howard Capital Management LP | 28,478 | $56.7K | 0.00% | +28,478 | New |
| BNP Paribas Arbitrage, SA | 31,322 | $62.3K | 0.00% | +11,226+55.9% | Added |
| Cerity Partners LLC | 31,387 | $62.5K | 0.00% | +31,387 | New |
| Crestwood Advisors Group LLC | 31,687 | $63.1K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 33,918 | $67.5K | 0.00% | +1,419+4.4% | Added |
| Ieq Capital, LLC | 34,882 | $69.4K | 0.00% | +34,882 | New |
| Levin Capital Strategies, L.P. | 35,000 | $69.7K | 0.01% | −40,000−53.3% | Reduced |
| JPMorgan Chase & Co | 35,663 | $71.0K | 0.00% | +23+0.1% | Added |
| Verition Fund Management LLC | 38,255 | $76.1K | 0.00% | −65,290−63.1% | Reduced |
| Skopos Labs, Inc. | 39,967 | $79.5K | 0.02% | +38,073+2,010.2% | Added |
| Citigroup Inc | 42,302 | $84.2K | 0.00% | −5,129−10.8% | Reduced |
| TD Asset Management Inc | 46,434 | $92.4K | 0.00% | 00.0% | Unchanged |
| Jacobs Levy Equity Management, Inc | 50,514 | $100.5K | 0.00% | +50,514 | New |
| SG Americas Securities, LLC | 51,456 | $102.0K | 0.00% | −8,773−14.6% | Reduced |
| Two Sigma Advisers, LP | 53,900 | $107.3K | 0.00% | +10,700+24.8% | Added |
| Virtus Investment Advisers, Inc. | 54,535 | $108.5K | 0.03% | +54,535 | New |
| Intech Investment Management LLC | 54,946 | $109.3K | 0.00% | +24,542+80.7% | Added |
| Tudor Investment Corp Et Al | 60,368 | $120.1K | 0.00% | +60,368 | New |
| Barclays PLC | 71,424 | $142.1K | 0.00% | −26,197−26.8% | Reduced |
| Alliancebernstein L.P. | 76,000 | $151.2K | 0.00% | 00.0% | Unchanged |
| Vestmark Advisory Solutions, Inc. | 78,599 | $156.4K | 0.00% | −32,866−29.5% | Reduced |
| Rhumbline Advisers | 81,900 | $163.0K | 0.00% | +9,944+13.8% | Added |
| Green Alpha Advisors, LLC | 83,467 | $166.1K | 0.18% | +19,061+29.6% | Added |
| Davy Global Fund Management Ltd | 89,870 | $178.8K | 0.02% | +29,185+48.1% | Added |
| Wells Fargo & Company | 90,819 | $180.7K | 0.00% | −5,362−5.6% | Reduced |
| Palumbo Wealth Management LLC | 95,462 | $190.0K | 0.06% | +95,462 | New |
| Bank of America Corp | 112,926 | $224.7K | 0.00% | −317,687−73.8% | Reduced |
| UBS Group AG | 117,680 | $234.2K | 0.00% | −100,506−46.1% | Reduced |
| FIL Ltd | 121,017 | $240.8K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 126,846 | $252.4K | 0.00% | +46,011+56.9% | Added |
| Susquehanna International Group, LLP | 142,619 | $283.8K | 0.00% | +105,567+284.9% | Added |
| Gsa Capital Partners LLP | 153,273 | $305.0K | 0.03% | +137,962+901.1% | Added |
| Bank of New York Mellon Corp | 155,992 | $310.4K | 0.00% | +26,478+20.4% | Added |
| Nuveen, LLC | 59,402 | $373.7K | 0.00% | +59,402 | New |
| Chelsea Counsel Co | 208,210 | $414.3K | 0.23% | +21,430+11.5% | Added |
| AQR Capital Management LLC | 243,795 | $485.2K | 0.00% | +227,749+1,419.4% | Added |
| Goldman Sachs Group Inc | 251,399 | $500.3K | 0.00% | −170,499−40.4% | Reduced |
| Two Sigma Investments, LP | 258,770 | $515.0K | 0.00% | +92,571+55.7% | Added |
| Morgan Stanley | 355,176 | $706.8K | 0.00% | +43,900+14.1% | Added |