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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

13F holders, Q3 2024

Institutional positions in Prime Medicine, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
116
−3 vs. Q2 2024
Shares held
68.7M
+5.01M (+7.9%) vs. Q2 2024
Total value
$265.9M
−$61.5M (−18.8%) vs. Q2 2024
New holders
15
38 more added
Sold out
18
33 more reduced

3 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 116 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 66 institutionsQ1 2023: 76 institutionsQ2 2023: 79 institutionsQ3 2023: 83 institutionsQ4 2023: 105 institutionsQ1 2024: 115 institutionsQ2 2024: 122 institutionsQ3 2024: 116 institutionsQ4 2024: 132 institutionsQ1 2025: 125 institutionsQ2 2025: 121 institutionsQ3 2025: 167 institutionsQ4 2025: 183 institutionsQ1 2026: 192 institutionsQ2 2026: 187 institutions
Value heldQ3 2024: $265.9M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $767.8MQ1 2023: $512.1MQ2 2023: $675.7MQ3 2023: $472.3MQ4 2023: $431.4MQ1 2024: $466.6MQ2 2024: $354.0MQ3 2024: $265.9MQ4 2024: $188.0MQ1 2025: $120.4MQ2 2025: $145.0MQ3 2025: $511.5MQ4 2025: $336.5MQ1 2026: $342.6MQ2 2026: $393.5M
Institutions holding PRME and their total value by quarter
QuarterHoldersValue
Q2 2026187$393.5M
Q1 2026192$342.6M
Q4 2025183$336.5M
Q3 2025167$511.5M
Q2 2025121$145.0M
Q1 2025125$120.4M
Q4 2024132$188.0M
Q3 2024116$265.9M
Q2 2024122$354.0M
Q1 2024115$466.6M
Q4 2023105$431.4M
Q3 202383$472.3M
Q2 202379$675.7M
Q1 202376$512.1M
Q4 202266$767.8M
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q2 2024.

Institutions holding PRME in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP1,028,466$3.98M0.04%00.0%Unchanged
Vestal Point Capital, LP1,070,000$4.14M0.33%+620,000+137.8%Added
State Street Corp1,146,949$4.44M0.00%+43,086+3.9%Added
Geode Capital Management, LLC1,359,979$5.26M0.00%+63,456+4.9%Added
Price T Rowe Associates Inc1,545,961$5.98M0.00%00.0%Unchanged
MWG Management Limited1,792,210$6.94M7.68%00.0%Unchanged
Redmile Group, LLC2,074,350$8.03M0.47%00.0%Unchanged
Millennium Management LLC2,198,240$8.51M0.01%+867,313+65.2%Added
Nikko Asset Management Americas, Inc.3,182,455$12.3M0.14%−55,930−1.7%Reduced
Sumitomo Mitsui Trust Holdings, Inc.3,190,455$12.3M0.01%−47,930−1.5%Reduced
FMR LLC3,743,312$14.5M0.00%−184,541−4.7%Reduced
T. Rowe Price Investment Management, Inc.3,807,287$14.7M0.01%+81,560+2.2%Added
Vanguard Group Inc4,890,313$18.9M0.00%−1,188,540−19.6%Reduced
BlackRock, Inc.5,266,775$20.4M0.00%+5,266,775New
ARK Investment Management LLCSuperinvestorARK Invest5,660,719$21.9M0.20%−466,054−7.6%Reduced
Alphabet Inc.15,062,498$58.3M3.16%00.0%Unchanged
Ensign Peak Advisors, Inc0$00.00%−103,190−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−62,093−100.0%Sold out
Royce & Associates LP0$00.00%−60,999−100.0%Sold out
PDT Partners, LLC0$00.00%−49,325−100.0%Sold out
Virtu Financial LLC0$00.00%−42,741−100.0%Sold out
Wellington Management Group LLP0$00.00%−37,646−100.0%Sold out
AQR Capital Management LLC0$00.00%−34,268−100.0%Sold out
Susquehanna Portfolio Strategies, LLC0$00.00%−29,247−100.0%Sold out
Cornercap Investment Counsel Inc0$00.00%−28,923−100.0%Sold out
Green Alpha Advisors, LLC0$00.00%−26,245−100.0%Sold out
Alpine Global Management, LLC0$00.00%−17,373−100.0%Sold out
Principal Financial Group Inc0$00.00%−12,187−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−12,101−100.0%Sold out
STRS Ohio0$00.00%−10,000−100.0%Sold out
ORG Partners LLC0$00.00%−5,270−100.0%Sold out
nVerses Capital, LLC0$00.00%−3,500−100.0%Sold out
Group One Trading, L.P.0$00.00%−1,975−100.0%Sold out
Avion Wealth0$00.00%−79−100.0%Sold out
BlackRock Inc.––––Not filed
Susquehanna Fundamental Investments, LLC––––Not filed
Benjamin F. Edwards & Company, Inc.––––Not filed