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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Prime Medicine, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
122
+7 vs. Q1 2024
Shares held
68.9M
+2.23M (+3.3%) vs. Q1 2024
Total value
$354.0M
−$112.6M (−24.1%) vs. Q1 2024
New holders
26
45 more added
Sold out
19
31 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 122 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 66 institutionsQ1 2023: 76 institutionsQ2 2023: 79 institutionsQ3 2023: 83 institutionsQ4 2023: 105 institutionsQ1 2024: 115 institutionsQ2 2024: 122 institutionsQ3 2024: 116 institutionsQ4 2024: 132 institutionsQ1 2025: 125 institutionsQ2 2025: 121 institutionsQ3 2025: 167 institutionsQ4 2025: 183 institutionsQ1 2026: 192 institutionsQ2 2026: 187 institutions
Value heldQ2 2024: $354.0M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $767.8MQ1 2023: $512.1MQ2 2023: $675.7MQ3 2023: $472.3MQ4 2023: $431.4MQ1 2024: $466.6MQ2 2024: $354.0MQ3 2024: $265.9MQ4 2024: $188.0MQ1 2025: $120.4MQ2 2025: $145.0MQ3 2025: $511.5MQ4 2025: $336.5MQ1 2026: $342.6MQ2 2026: $393.5M
Institutions holding PRME and their total value by quarter
QuarterHoldersValue
Q2 2026187$393.5M
Q1 2026192$342.6M
Q4 2025183$336.5M
Q3 2025167$511.5M
Q2 2025121$145.0M
Q1 2025125$120.4M
Q4 2024132$188.0M
Q3 2024116$265.9M
Q2 2024122$354.0M
Q1 2024115$466.6M
Q4 2023105$431.4M
Q3 202383$472.3M
Q2 202379$675.7M
Q1 202376$512.1M
Q4 202266$767.8M
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2024.

Institutions holding PRME in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Samsara BioCapital, LLC540,304$2.78M0.58%00.0%Unchanged
Greenwich Wealth Management LLC653,001$3.36M0.25%+75,000+13.0%Added
Two Sigma Investments, LP681,476$3.50M0.01%+173,398+34.1%Added
Avidity Partners Management LP694,000$3.57M0.15%−1,296,000−65.1%Reduced
EcoR1 Capital, LLC700,000$3.60M0.11%00.0%Unchanged
Farallon Capital Management, L.L.C.750,000$3.85M0.02%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)896,960$4.61M0.08%+11,646+1.3%Added
Baker Bros. Advisors LP1,028,466$5.29M0.07%00.0%Unchanged
State Street Corp1,103,863$5.67M0.00%+325,081+41.7%Added
Geode Capital Management, LLC1,296,523$6.67M0.00%+379,662+41.4%Added
Millennium Management LLC1,330,927$6.84M0.01%+895,610+205.7%Added
Price T Rowe Associates Inc1,545,961$7.95M0.00%−976,629−38.7%Reduced
MWG Management Limited1,792,210$9.21M10.06%00.0%Unchanged
Redmile Group, LLC2,074,350$10.7M0.64%00.0%Unchanged
Nikko Asset Management Americas, Inc.3,238,385$16.5M0.19%−126,278−3.8%Reduced
Sumitomo Mitsui Trust Holdings, Inc.3,238,385$16.6M0.01%−126,278−3.8%Reduced
T. Rowe Price Investment Management, Inc.3,725,727$19.2M0.01%+635,644+20.6%Added
FMR LLC3,927,853$20.2M0.00%+3,483+0.1%Added
BlackRock Inc.5,110,418$26.3M0.00%+1,354,208+36.1%Added
Vanguard Group Inc6,078,853$31.2M0.00%+277,408+4.8%Added
ARK Investment Management LLCSuperinvestorARK Invest6,126,773$31.5M0.28%+133,419+2.2%Added
Alphabet Inc.15,062,498$77.4M3.92%00.0%Unchanged
Renaissance Technologies LLC0$00.00%−362,400−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−330,500−100.0%Sold out
Deep Track Capital, LP0$00.00%−303,716−100.0%Sold out
TrueMark Investments, LLC0$00.00%−85,183−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−61,295−100.0%Sold out
Bank of Montreal0$00.00%−46,637−100.0%Sold out
HRT Financial LP0$00.00%−41,000−100.0%Sold out
Cinctive Capital Management LP0$00.00%−33,033−100.0%Sold out
Brandywine Managers, LLC0$00.00%−32,977−100.0%Sold out
Verition Fund Management LLC0$00.00%−29,515−100.0%Sold out
Levin Capital Strategies, L.P.0$00.00%−26,500−100.0%Sold out
American International Group, Inc.0$00.00%−19,496−100.0%Sold out
Red Lighthouse Investment Management, LLC0$00.00%−14,950−100.0%Sold out
Walleye Capital LLC0$00.00%−10,443−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−7,997−100.0%Sold out
Simplex Trading, LLC0$00.00%−4,837−100.0%Sold out
Federated Hermes, Inc.0$00.00%−3,576−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−2,203−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−36−100.0%Sold out