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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2024

Institutional positions in Prime Medicine, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
122
+7 vs. Q1 2024
Shares held
68.9M
+2.23M (+3.3%) vs. Q1 2024
Total value
$354.0M
−$112.6M (−24.1%) vs. Q1 2024
New holders
26
45 more added
Sold out
19
31 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 122 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 66 institutionsQ1 2023: 76 institutionsQ2 2023: 79 institutionsQ3 2023: 83 institutionsQ4 2023: 105 institutionsQ1 2024: 115 institutionsQ2 2024: 122 institutionsQ3 2024: 116 institutionsQ4 2024: 132 institutionsQ1 2025: 125 institutionsQ2 2025: 121 institutionsQ3 2025: 167 institutionsQ4 2025: 183 institutionsQ1 2026: 192 institutionsQ2 2026: 187 institutions
Value heldQ2 2024: $354.0M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $767.8MQ1 2023: $512.1MQ2 2023: $675.7MQ3 2023: $472.3MQ4 2023: $431.4MQ1 2024: $466.6MQ2 2024: $354.0MQ3 2024: $265.9MQ4 2024: $188.0MQ1 2025: $120.4MQ2 2025: $145.0MQ3 2025: $511.5MQ4 2025: $336.5MQ1 2026: $342.6MQ2 2026: $393.5M
Institutions holding PRME and their total value by quarter
QuarterHoldersValue
Q2 2026187$393.5M
Q1 2026192$342.6M
Q4 2025183$336.5M
Q3 2025167$511.5M
Q2 2025121$145.0M
Q1 2025125$120.4M
Q4 2024132$188.0M
Q3 2024116$265.9M
Q2 2024122$354.0M
Q1 2024115$466.6M
Q4 2023105$431.4M
Q3 202383$472.3M
Q2 202379$675.7M
Q1 202376$512.1M
Q4 202266$767.8M
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q1 2024.

Institutions holding PRME in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Lazard Asset Management LLC72$00.00%−1,042−93.5%Reduced
Avion Wealth79$00.00%+8+11.3%Added
Covestor Ltd14$00.00%00.0%Unchanged
Farther Finance Advisors, LLC26$1420.00%00.0%Unchanged
Russell Investments Group, Ltd.81$4160.00%+81New
The PNC Financial Services Group, Inc.114$5860.00%+114New
EverSource Wealth Advisors, LLC106$5950.00%+106New
SRS Capital Advisors, Inc.139$7150.00%+139New
Principal Securities, Inc.165$8480.00%−32−16.2%Reduced
Benjamin Edwards Inc186$1.00K0.00%−121−39.4%Reduced
GAMMA Investing LLC232$1.19K0.00%+232New
Abich Financial Wealth Management LLC306$1.57K0.00%+282+1,175.0%Added
Daiwa Securities Group Inc.398$2.00K0.00%00.0%Unchanged
CWM, LLC326$2.00K0.00%+276+552.0%Added
Comerica Bank496$2.55K0.00%−155−23.8%Reduced
Fairman Group, LLC500$2.57K0.00%00.0%Unchanged
Signaturefd, LLC1,000$5.14K0.00%+1,000New
First Horizon Advisors, Inc.1,134$5.83K0.00%00.0%Unchanged
Amalgamated Bank1,347$7.00K0.00%00.0%Unchanged
Group One Trading, L.P.1,975$10.2K0.00%+1,975New
nVerses Capital, LLC3,500$18.0K0.01%+3,500New
Mirae Asset Global Investments Co., Ltd.3,584$19.1K0.00%+3,584New
Ameritas Investment Partners, Inc.3,901$20.1K0.00%00.0%Unchanged
California State Teachers Retirement System4,110$21.1K0.00%+132+3.3%Added
Tower Research Capital LLC (TRC)5,157$26.5K0.00%−1,906−27.0%Reduced
ORG Partners LLC5,270$28.9K0.00%+5,270New
Royal Bank of Canada6,138$31.0K0.00%+4,449+263.4%Added
Legal & General Group Plc6,279$32.3K0.00%+1,943+44.8%Added
National Bank of Canada6,200$33.9K0.00%+6,200New
Nisa Investment Advisors, LLC7,736$39.8K0.00%+7,702+22,652.9%Added
New York State Common Retirement Fund8,434$43.4K0.00%+11+0.1%Added
STRS Ohio10,000$51.4K0.00%−24,000−70.6%Reduced
Brown Brothers Harriman & Co10,065$51.7K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.10,701$55.0K0.00%−908−7.8%Reduced
CIBC World Markets Inc.11,335$58.0K0.00%−712−5.9%Reduced
State Board of Administration of Florida Retirement System11,420$58.7K0.00%+11,420New
Virtus ETF Advisers LLC11,459$58.9K0.03%+11,459New
Balyasny Asset Management LLC12,101$62.2K0.00%+12,101New
Principal Financial Group Inc12,187$62.6K0.00%−5,446−30.9%Reduced
ProShare Advisors LLC12,707$65.3K0.00%−2,569−16.8%Reduced
Citadel Advisors LLC12,726$65.4K0.00%−95,472−88.2%Reduced
Invesco Ltd.13,437$69.1K0.00%+2,826+26.6%Added
China Universal Asset Management Co., Ltd.14,101$72.5K0.01%−8,277−37.0%Reduced
Clarius Group, LLC16,080$82.7K0.01%00.0%Unchanged
Alpine Global Management, LLC17,373$89.3K0.02%+17,373New
Citigroup Inc17,511$90.0K0.00%−26,459−60.2%Reduced
Davy Global Fund Management Ltd18,914$97.2K0.01%+18,914New
Barclays PLC19,104$98.2K0.00%−8,486−30.8%Reduced
Voya Investment Management LLC19,184$98.6K0.00%+6,278+48.6%Added
Mirae Asset Global ETFs Holdings Ltd.19,524$100.4K0.00%+19,524New
Wells Fargo & Company20,358$104.6K0.00%+8,548+72.4%Added
Oppenheimer & Co Inc21,031$108.1K0.00%+855+4.2%Added
Envestnet Asset Management Inc21,660$111.3K0.00%−1,220−5.3%Reduced
HighTower Advisors, LLC22,234$113.0K0.00%−52−0.2%Reduced
UBS Group AG22,539$115.8K0.00%−19,984−47.0%Reduced
Manufacturers Life Insurance Company, The24,138$124.1K0.00%−50,790−67.8%Reduced
Benjamin F. Edwards & Company, Inc.25,326$130.0K0.00%+24,899+5,831.1%Added
Green Alpha Advisors, LLC26,245$134.9K0.11%−7,493−22.2%Reduced
Cornercap Investment Counsel Inc28,923$148.7K0.02%−318−1.1%Reduced
Susquehanna Portfolio Strategies, LLC29,247$150.3K0.01%−87,640−75.0%Reduced
Ameriprise Financial Inc29,896$153.7K0.00%+29,896New
Corebridge Financial, Inc.30,512$156.8K0.00%+30,512New
PEAK6 Investments LLC34,000$174.8K0.01%+17,000+100.0%Added
MetLife Investment Management34,128$175.4K0.00%+12,866+60.5%Added
AQR Capital Management LLC34,268$176.1K0.00%+34,268New
Wellington Management Group LLP37,646$193.5K0.00%+37,646New
JPMorgan Chase & Co38,187$196.3K0.00%−3,894−9.3%Reduced
Virtu Financial LLC42,741$220.0K0.02%+42,741New
D. E. Shaw & Co., Inc.45,435$233.5K0.00%+18,767+70.4%Added
Voloridge Investment Management, LLC45,753$235.2K0.00%+45,753New
TD Asset Management Inc46,434$238.7K0.00%−82,588−64.0%Reduced
PDT Partners, LLC49,325$253.5K0.02%+49,325New
Susquehanna Fundamental Investments, LLC49,379$253.8K0.01%+28,204+133.2%Added
Royce & Associates LP60,999$313.5K0.00%+14,785+32.0%Added
Thrivent Financial for Lutherans62,093$319.0K0.00%+62,093New
Squarepoint Ops LLC63,461$326.2K0.00%+3,895+6.5%Added
Rhumbline Advisers70,107$360.3K0.00%+17,595+33.5%Added
Alliancebernstein L.P.70,190$360.8K0.00%+32,240+85.0%Added
Chelsea Counsel Co77,690$399.3K0.20%+72,690+1,453.8%Added
Goldman Sachs Group Inc79,367$407.9K0.00%+41,187+107.9%Added
Ensign Peak Advisors, Inc103,190$530.4K0.00%−46,810−31.2%Reduced
Vestmark Advisory Solutions, Inc.103,512$532.1K0.02%−43,972−29.8%Reduced
Susquehanna International Group, LLP105,892$544.3K0.00%+84,580+396.9%Added
Sphera Funds Management Ltd.127,424$655.0K0.11%−77,818−37.9%Reduced
FIL Ltd138,276$710.7K0.00%00.0%Unchanged
Jane Street Group, LLC168,417$865.7K0.00%+140,949+513.1%Added
Bank of New York Mellon Corp170,563$876.7K0.00%+64,600+61.0%Added
Two Sigma Advisers, LP176,500$907.2K0.00%+12,500+7.6%Added
Morgan Stanley183,965$945.6K0.00%−14,501−7.3%Reduced
Trexquant Investment LP228,215$1.17M0.02%+228,215New
Westwood Holdings Group Inc.358,580$1.84M0.01%+199,229+125.0%Added
Bollard Group LLC361,136$1.86M0.05%00.0%Unchanged
Casdin Capital, LLC367,175$1.89M0.14%00.0%Unchanged
Nuveen Asset Management, LLC392,443$2.02M0.00%+242,070+161.0%Added
Northern Trust Corp393,517$2.02M0.00%+53,519+15.7%Added
Bank of America Corp427,396$2.20M0.00%+5,976+1.4%Added
Vestal Point Capital, LP450,000$2.31M0.17%+90,000+25.0%Added
Deutsche Bank AG460,995$2.37M0.00%+440,280+2,125.4%Added
Charles Schwab Investment Management Inc492,261$2.53M0.00%+194,438+65.3%Added
Moore Capital Management, LP500,000$2.57M0.06%00.0%Unchanged