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Prime Medicine, Inc.

PRME
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001894562

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

13F holders, Q1 2024

Institutional positions in Prime Medicine, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
115
+10 vs. Q4 2023
Shares held
66.7M
+18.0M (+36.9%) vs. Q4 2023
Total value
$466.6M
+$35.1M (+8.1%) vs. Q4 2023
New holders
23
39 more added
Sold out
13
35 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 115 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 66 institutionsQ1 2023: 76 institutionsQ2 2023: 79 institutionsQ3 2023: 83 institutionsQ4 2023: 105 institutionsQ1 2024: 115 institutionsQ2 2024: 122 institutionsQ3 2024: 116 institutionsQ4 2024: 132 institutionsQ1 2025: 125 institutionsQ2 2025: 121 institutionsQ3 2025: 167 institutionsQ4 2025: 183 institutionsQ1 2026: 192 institutionsQ2 2026: 187 institutions
Value heldQ1 2024: $466.6M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $767.8MQ1 2023: $512.1MQ2 2023: $675.7MQ3 2023: $472.3MQ4 2023: $431.4MQ1 2024: $466.6MQ2 2024: $354.0MQ3 2024: $265.9MQ4 2024: $188.0MQ1 2025: $120.4MQ2 2025: $145.0MQ3 2025: $511.5MQ4 2025: $336.5MQ1 2026: $342.6MQ2 2026: $393.5M
Institutions holding PRME and their total value by quarter
QuarterHoldersValue
Q2 2026187$393.5M
Q1 2026192$342.6M
Q4 2025183$336.5M
Q3 2025167$511.5M
Q2 2025121$145.0M
Q1 2025125$120.4M
Q4 2024132$188.0M
Q3 2024116$265.9M
Q2 2024122$354.0M
Q1 2024115$466.6M
Q4 2023105$431.4M
Q3 202383$472.3M
Q2 202379$675.7M
Q1 202376$512.1M
Q4 202266$767.8M
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q4 2023.

Institutions holding PRME in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Deerfield Management Company, L.P. (Series C)885,314$6.20M0.11%00.0%Unchanged
Geode Capital Management, LLC916,861$6.42M0.00%+29,358+3.3%Added
Baker Bros. Advisors LP1,028,466$7.20M0.09%00.0%Unchanged
MWG Management Limited1,792,210$12.5M9.29%00.0%Unchanged
Avidity Partners Management LP1,990,000$13.9M0.50%+1,990,000New
Redmile Group, LLC2,074,350$14.5M0.53%+750,000+56.6%Added
Price T Rowe Associates Inc2,522,590$17.7M0.00%+301,431+13.6%Added
T. Rowe Price Investment Management, Inc.3,090,083$21.6M0.01%+3,090,083New
Nikko Asset Management Americas, Inc.3,364,663$23.5M0.23%−154,366−4.4%Reduced
Sumitomo Mitsui Trust Holdings, Inc.3,364,663$23.6M0.02%−154,366−4.4%Reduced
BlackRock Inc.3,756,210$26.3M0.00%−22,408−0.6%Reduced
FMR LLC3,924,370$27.5M0.00%−9760.0%Reduced
Vanguard Group Inc5,801,445$40.6M0.00%+1,746,534+43.1%Added
ARK Investment Management LLCSuperinvestorARK Invest5,993,354$42.0M0.29%+2,855,084+91.0%Added
Alphabet Inc.15,062,498$105.4M4.19%+3,200,000+27.0%Added
Woodline Partners LP0$00.00%−120,060−100.0%Sold out
Trexquant Investment LP0$00.00%−26,983−100.0%Sold out
Mirae Asset Global Investments Co., Ltd.0$00.00%−21,301−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−12,195−100.0%Sold out
Amundi0$00.00%−11,770−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−11,420−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−10,193−100.0%Sold out
SG Americas Securities, LLC0$00.00%−10,128−100.0%Sold out
ORG Partners LLC0$00.00%−5,270−100.0%Sold out
Advisory Services Network, LLC0$00.00%−1,153−100.0%Sold out
Sandia Investment Management LP0$00.00%−1,084−100.0%Sold out
Glassman Wealth Services0$00.00%−103−100.0%Sold out
GAMMA Investing LLC0$00.00%−118−100.0%Sold out