Prime Medicine, Inc.
PRME- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001894562
No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2024
Institutional positions in Prime Medicine, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 115
- +10 vs. Q4 2023
- Shares held
- 66.7M
- +18.0M (+36.9%) vs. Q4 2023
- Total value
- $466.6M
- +$35.1M (+8.1%) vs. Q4 2023
- New holders
- 23
- 39 more added
- Sold out
- 13
- 35 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRME on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 187 | $393.5M |
| Q1 2026 | 192 | $342.6M |
| Q4 2025 | 183 | $336.5M |
| Q3 2025 | 167 | $511.5M |
| Q2 2025 | 121 | $145.0M |
| Q1 2025 | 125 | $120.4M |
| Q4 2024 | 132 | $188.0M |
| Q3 2024 | 116 | $265.9M |
| Q2 2024 | 122 | $354.0M |
| Q1 2024 | 115 | $466.6M |
| Q4 2023 | 105 | $431.4M |
| Q3 2023 | 83 | $472.3M |
| Q2 2023 | 79 | $675.7M |
| Q1 2023 | 76 | $512.1M |
| Q4 2022 | 66 | $767.8M |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Prime Medicine, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| CWM, LLC | 50 | $0 | 0.00% | +4+8.7% | Added |
| Covestor Ltd | 14 | $0 | 0.00% | −1−6.7% | Reduced |
| Abich Financial Wealth Management LLC | 24 | $168 | 0.00% | +24 | New |
| Farther Finance Advisors, LLC | 26 | $176 | 0.00% | +26 | New |
| Nisa Investment Advisors, LLC | 34 | $238 | 0.00% | +10+41.7% | Added |
| Riggs Asset Managment Co. Inc. | 36 | $252 | 0.00% | +36 | New |
| Avion Wealth | 71 | $1.00K | 0.00% | +71 | New |
| Principal Securities, Inc. | 197 | $1.38K | 0.00% | −55−21.8% | Reduced |
| Benjamin Edwards Inc | 307 | $2.00K | 0.00% | −7−2.2% | Reduced |
| Daiwa Securities Group Inc. | 398 | $3.00K | 0.00% | 00.0% | Unchanged |
| Benjamin F. Edwards & Company, Inc. | 427 | $3.00K | 0.00% | +427 | New |
| Fairman Group, LLC | 500 | $3.50K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 651 | $4.56K | 0.00% | −663−50.5% | Reduced |
| Lazard Asset Management LLC | 1,114 | $7.00K | 0.00% | −618−35.7% | Reduced |
| First Horizon Advisors, Inc. | 1,134 | $7.94K | 0.00% | +324+40.0% | Added |
| Amalgamated Bank | 1,347 | $9.00K | 0.00% | −4,266−76.0% | Reduced |
| Royal Bank of Canada | 1,689 | $12.0K | 0.00% | −10,484−86.1% | Reduced |
| Metropolitan Life Insurance Co | 2,203 | $15.4K | 0.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 3,576 | $25.0K | 0.00% | +3,576 | New |
| Ameritas Investment Partners, Inc. | 3,901 | $27.3K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 3,978 | $27.8K | 0.00% | −2,533−38.9% | Reduced |
| Legal & General Group Plc | 4,336 | $30.3K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 4,837 | $33.0K | 0.00% | +4,837 | New |
| Chelsea Counsel Co | 5,000 | $35.0K | 0.02% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,063 | $49.4K | 0.00% | −13,948−66.4% | Reduced |
| EntryPoint Capital, LLC | 7,997 | $56.0K | 0.05% | −27,238−77.3% | Reduced |
| New York State Common Retirement Fund | 8,423 | $59.0K | 0.00% | −17−0.2% | Reduced |
| Brown Brothers Harriman & Co | 10,065 | $70.5K | 0.00% | 00.0% | Unchanged |
| Walleye Capital LLC | 10,443 | $73.1K | 0.00% | −57,863−84.7% | Reduced |
| Invesco Ltd. | 10,611 | $74.3K | 0.00% | +10,611 | New |
| Advisor Group Holdings, Inc. | 11,609 | $81.3K | 0.00% | −1,961−14.5% | Reduced |
| Wells Fargo & Company | 11,810 | $82.7K | 0.00% | +1,581+15.5% | Added |
| CIBC World Markets Inc. | 12,047 | $84.0K | 0.00% | −214−1.7% | Reduced |
| Voya Investment Management LLC | 12,906 | $90.3K | 0.00% | −3,254−20.1% | Reduced |
| Red Lighthouse Investment Management, LLC | 14,950 | $104.7K | 0.04% | 00.0% | Unchanged |
| ProShare Advisors LLC | 15,276 | $106.9K | 0.00% | +2,520+19.8% | Added |
| Clarius Group, LLC | 16,080 | $112.6K | 0.01% | 00.0% | Unchanged |
| PEAK6 Investments LLC | 17,000 | $119.0K | 0.01% | −5,000−22.7% | Reduced |
| Principal Financial Group Inc | 17,633 | $123.4K | 0.00% | −257−1.4% | Reduced |
| American International Group, Inc. | 19,496 | $136.5K | 0.00% | −167−0.8% | Reduced |
| Oppenheimer & Co Inc | 20,176 | $141.2K | 0.00% | −422−2.0% | Reduced |
| Deutsche Bank AG | 20,715 | $145.0K | 0.00% | +614+3.1% | Added |
| Susquehanna Fundamental Investments, LLC | 21,175 | $148.2K | 0.01% | +21,175 | New |
| MetLife Investment Management | 21,262 | $148.8K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 21,312 | $149.2K | 0.00% | −25,273−54.3% | Reduced |
| HighTower Advisors, LLC | 22,286 | $153.0K | 0.00% | +1,169+5.5% | Added |
| China Universal Asset Management Co., Ltd. | 22,378 | $156.6K | 0.02% | +11,120+98.8% | Added |
| Envestnet Asset Management Inc | 22,880 | $160.2K | 0.00% | +510+2.3% | Added |
| Levin Capital Strategies, L.P. | 26,500 | $185.5K | 0.02% | +6,500+32.5% | Added |
| D. E. Shaw & Co., Inc. | 26,668 | $186.7K | 0.00% | +26,668 | New |
| Jane Street Group, LLC | 27,468 | $192.3K | 0.00% | −27,751−50.3% | Reduced |
| Barclays PLC | 27,590 | $193.1K | 0.00% | −26,645−49.1% | Reduced |
| Cornercap Investment Counsel Inc | 29,241 | $204.7K | 0.03% | +29,241 | New |
| Verition Fund Management LLC | 29,515 | $206.6K | 0.00% | +29,515 | New |
| Brandywine Managers, LLC | 32,977 | $230.8K | 0.23% | 00.0% | Unchanged |
| Cinctive Capital Management LP | 33,033 | $231.2K | 0.01% | +33,033 | New |
| Green Alpha Advisors, LLC | 33,738 | $236.2K | 0.17% | +4,200+14.2% | Added |
| STRS Ohio | 34,000 | $238.0K | 0.00% | +16,900+98.8% | Added |
| Alliancebernstein L.P. | 37,950 | $265.6K | 0.00% | +590+1.6% | Added |
| Goldman Sachs Group Inc | 38,180 | $267.3K | 0.00% | −12,969−25.4% | Reduced |
| HRT Financial LP | 41,000 | $287.0K | 0.00% | −18,116−30.6% | Reduced |
| JPMorgan Chase & Co | 42,081 | $294.6K | 0.00% | −3,438−7.6% | Reduced |
| UBS Group AG | 42,523 | $297.7K | 0.00% | +11,111+35.4% | Added |
| Citigroup Inc | 43,970 | $307.8K | 0.00% | +33,035+302.1% | Added |
| Royce & Associates LP | 46,214 | $323.5K | 0.00% | +6,377+16.0% | Added |
| Bank of Montreal | 46,637 | $327.4K | 0.00% | +1,637+3.6% | Added |
| Rhumbline Advisers | 52,512 | $367.6K | 0.00% | +1,654+3.3% | Added |
| Squarepoint Ops LLC | 59,566 | $417.0K | 0.00% | −11,957−16.7% | Reduced |
| Tudor Investment Corp Et Al | 61,295 | $429.1K | 0.01% | +61,295 | New |
| Manufacturers Life Insurance Company, The | 74,928 | $524.5K | 0.00% | +10,381+16.1% | Added |
| TrueMark Investments, LLC | 85,183 | $596.3K | 0.55% | +10,153+13.5% | Added |
| Bank of New York Mellon Corp | 105,963 | $741.7K | 0.00% | −8,283−7.3% | Reduced |
| Citadel Advisors LLC | 108,198 | $757.4K | 0.00% | +108,198 | New |
| Susquehanna Portfolio Strategies, LLC | 116,887 | $818.2K | 0.02% | 00.0% | Unchanged |
| TD Asset Management Inc | 129,022 | $903.2K | 0.00% | +76,280+144.6% | Added |
| FIL Ltd | 138,276 | $967.9K | 0.00% | −8,666−5.9% | Reduced |
| Vestmark Advisory Solutions, Inc. | 147,484 | $1.03M | 0.04% | +3,196+2.2% | Added |
| Ensign Peak Advisors, Inc | 150,000 | $1.05M | 0.00% | 00.0% | Unchanged |
| Nuveen Asset Management, LLC | 150,373 | $1.05M | 0.00% | +42,280+39.1% | Added |
| Westwood Holdings Group Inc. | 159,351 | $1.11M | 0.01% | +159,351 | New |
| Two Sigma Advisers, LP | 164,000 | $1.15M | 0.00% | +118,000+256.5% | Added |
| Morgan Stanley | 198,466 | $1.39M | 0.00% | −13,268−6.3% | Reduced |
| Sphera Funds Management Ltd. | 205,242 | $1.44M | 0.23% | +131,262+177.4% | Added |
| Charles Schwab Investment Management Inc | 297,823 | $2.08M | 0.00% | +1,635+0.6% | Added |
| Deep Track Capital, LP | 303,716 | $2.13M | 0.06% | +303,716 | New |
| Schonfeld Strategic Advisors LLC | 330,500 | $2.31M | 0.02% | +330,500 | New |
| Northern Trust Corp | 339,998 | $2.38M | 0.00% | −4,929−1.4% | Reduced |
| Vestal Point Capital, LP | 360,000 | $2.52M | 0.21% | +339,694+1,672.9% | Added |
| Bollard Group LLC | 361,136 | $2.53M | 0.08% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 362,400 | $2.54M | 0.00% | +309,108+580.0% | Added |
| Casdin Capital, LLC | 367,175 | $2.57M | 0.19% | 00.0% | Unchanged |
| Bank of America Corp | 421,420 | $2.95M | 0.00% | −49,176−10.4% | Reduced |
| Millennium Management LLC | 435,317 | $3.05M | 0.00% | +300,773+223.5% | Added |
| Moore Capital Management, LP | 500,000 | $3.50M | 0.07% | +500,000 | New |
| Two Sigma Investments, LP | 508,078 | $3.56M | 0.01% | +239,716+89.3% | Added |
| Samsara BioCapital, LLC | 540,304 | $3.78M | 0.59% | +70,000+14.9% | Added |
| Greenwich Wealth Management LLC | 578,001 | $4.05M | 0.32% | +65,000+12.7% | Added |
| EcoR1 Capital, LLC | 700,000 | $4.90M | 0.12% | +700,000 | New |
| Farallon Capital Management, L.L.C. | 750,000 | $5.25M | 0.03% | +750,000 | New |
| State Street Corp | 778,782 | $5.45M | 0.00% | +19,024+2.5% | Added |