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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Prelude Therapeutics Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
75
+21 vs. Q1 2026
Shares held
49.6M
+18.8M (+61.2%) vs. Q1 2026
Total value
$264.3M
+$159.1M (+151.2%) vs. Q1 2026
New holders
34
25 more added
Sold out
13
8 more reduced

1 institution that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 75 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ2 2026: $264.3M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q1 2026.

Institutions holding PRLD in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Optiver Holding B.V.4$210.00%−16−80.0%Reduced
Caitong International Asset Management Co., Ltd18$960.00%+18New
SBI Securities Co., Ltd.22$1170.00%−2,619−99.2%Reduced
Sterling Capital Management LLC97$5170.00%+97New
Fortitude Family Office, LLC230$1.23K0.00%00.0%Unchanged
Quarry LP755$4.02K0.00%+755New
The PNC Financial Services Group, Inc.1,171$6.24K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC1,634$8.71K0.00%00.0%Unchanged
Russell Investments Group, Ltd.2,220$11.8K0.00%+2,220New
Tower Research Capital LLC (TRC)2,377$12.7K0.00%+2,377New
Ameritas Investment Partners, Inc.2,520$13.4K0.00%+2,520New
Royal Bank of Canada2,658$14.0K0.00%+327+14.0%Added
Legal & General Group Plc2,699$14.4K0.00%+2,699New
Group One Trading, L.P.3,907$20.8K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA4,104$21.9K0.00%+4,009+4,220.0%Added
STRS Ohio5,500$29.3K0.00%+5,500New
FMR LLC5,629$30.0K0.00%−380−6.3%Reduced
Los Angeles Capital Management LLC6,430$34.3K0.00%+6,430New
Alliancebernstein L.P.10,530$36.0K0.00%+10,530New
Police & Firemen's Retirement System of New Jersey10,492$55.9K0.00%+10,492New
Spark Investment Management LLC10,600$56.5K0.11%+10,600New
JPMorgan Chase & Co13,538$66.7K0.00%+13,476+21,735.5%Added
Gsa Capital Partners LLP12,672$68.0K0.00%+12,672New
Mirae Asset Global ETFs Holdings Ltd.12,784$68.1K0.00%+12,784New
Citigroup Inc13,033$69.5K0.00%+13,028+260,560.0%Added
Qube Research & Technologies Ltd13,110$69.9K0.00%−3,307−20.1%Reduced
Mangrove Partners13,352$71.2K0.00%+13,352New
HSBC Holdings PLC13,652$74.4K0.00%00.0%Unchanged
New York State Common Retirement Fund14,200$75.7K0.00%+14,200New
Barclays PLC14,529$77.4K0.00%+5,929+68.9%Added
ExodusPoint Capital Management, LP15,475$82.5K0.00%+15,475New
Vanguard Global Advisers, LLC16,210$86.4K0.00%+11,574+249.7%Added
Rhumbline Advisers22,074$117.6K0.00%+22,074New
Citadel Advisors LLC22,554$120.2K0.00%−101,824−81.9%Reduced
Price T Rowe Associates Inc22,758$122.0K0.00%+22,758New
Bank of America Corp23,875$127.3K0.00%−32,650−57.8%Reduced
Wells Fargo & Company25,325$135.0K0.00%+25,325New
Deutsche Bank AG27,824$148.3K0.00%+27,824New
Graham Capital Management, L.P.29,770$158.7K0.00%+18,427+162.5%Added
State of Wyoming32,862$175.2K0.02%+32,862New
Cerity Partners LLC32,875$175.2K0.00%00.0%Unchanged
Invesco Ltd.34,742$185.2K0.00%+34,742New
Dimensional Fund Advisors LP35,210$186.8K0.00%00.0%Unchanged
Nuveen, LLC37,023$197.3K0.00%+37,023New
Mariner, LLC45,261$241.2K0.00%+45,261New
Panagora Asset Management Inc47,574$253.6K0.00%+47,574New
Squarepoint Ops LLC59,540$317.3K0.00%+59,540New
Bridgeway Capital Management, LLC64,500$343.8K0.01%+11,000+20.6%Added
Charles Schwab Investment Management Inc67,622$360.4K0.00%+67,622New
Bank of New York Mellon Corp68,187$363.4K0.00%+68,187New
Hillsdale Investment Management Inc.81,400$433.9K0.01%+81,400New
Goldman Sachs Group Inc120,834$644.0K0.00%−115,635−48.9%Reduced
Connor, Clark & Lunn Investment Management Ltd.125,606$669.5K0.00%+16,521+15.1%Added
Marshall Wace, LLP190,692$1.02M0.00%−168,214−46.9%Reduced
Vanguard Portfolio Management LLC193,920$1.03M0.00%+193,920New
Northern Trust Corp240,599$1.28M0.00%+190,479+380.0%Added
Renaissance Technologies LLC281,200$1.50M0.00%+6,000+2.2%Added
Vanguard Fiduciary Trust Co284,886$1.52M0.00%+127,506+81.0%Added
UBS Group AG318,797$1.70M0.00%+254,292+394.2%Added
State Street Corp428,787$2.29M0.00%+290,556+210.2%Added
Morgan Stanley503,860$2.69M0.00%+181,699+56.4%Added
Acadian Asset Management LLC611,359$3.25M0.00%+99,840+19.5%Added
Adage Capital Partners GP, L.L.C.766,095$4.08M0.01%+766,095New
Geode Capital Management, LLC841,862$4.49M0.00%+539,404+178.3%Added
Millennium Management LLC844,993$4.50M0.00%+462,256+120.8%Added
ADAR1 Capital Management, LLC900,900$4.80M0.23%+748,075+489.5%Added
Two Sigma Investments, LP993,369$5.29M0.00%+69,743+7.6%Added
Sphera Funds Management Ltd.1,019,832$5.44M0.78%+461,493+82.7%Added
BlackRock, Inc.1,797,501$9.58M0.00%+1,475,615+458.4%Added
Vanguard Capital Management LLC2,009,445$10.7M0.00%+779,039+63.3%Added
Kynam Capital Management, LP2,415,087$12.9M0.71%+822,536+51.6%Added
Soleus Capital Management, L.P.3,378,378$18.0M0.62%+3,378,378New
Ra Capital Management, L.P.6,475,882$34.5M0.30%+6,475,882New
Baker Bros. Advisors LP10,123,824$54.0M0.27%00.0%Unchanged
OrbiMed Advisors LLC13,724,571$73.2M1.39%+2,815,315+25.8%Added
EcoR1 Capital, LLC0$00.00%−947,049−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−267,788−100.0%Sold out
Jane Street Group, LLC0$00.00%−192,963−100.0%Sold out
HRT Financial LP0$00.00%−58,699−100.0%Sold out
XTX Topco Ltd0$00.00%−57,190−100.0%Sold out
Colony Group, LLC0$00.00%−50,007−100.0%Sold out
Omers Administration Corp0$00.00%−32,700−100.0%Sold out
Prudential Financial Inc0$00.00%−17,420−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−16,329−100.0%Sold out
Diametric Capital, LP0$00.00%−11,980−100.0%Sold out
Nine Masts Capital Ltd0$00.00%−11,699−100.0%Sold out
American Century Companies Inc0$00.00%−10,294−100.0%Sold out
Caldwell Sutter Capital, Inc.0$00.00%−1,000−100.0%Sold out
CWM, LLC––––Not filed