Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 368
- +41 vs. Q4 2025
- Shares held
- 28.4M
- +3.02M (+11.9%) vs. Q4 2025
- Total value
- $7.32B
- +$1.08B (+17.2%) vs. Q4 2025
- New holders
- 76
- 138 more added
- Sold out
- 35
- 105 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| RSM US Wealth Management LLC | 852 | $220.1K | 0.00% | +852 | New |
| DRW Securities, LLC | 857 | $221.4K | 0.01% | +857 | New |
| GAMMA Investing LLC | 858 | $221.6K | 0.01% | +69+8.7% | Added |
| CIBC Asset Management Inc | 888 | $229.4K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 937 | $242.0K | 0.00% | +7+0.8% | Added |
| Coldstream Capital Management Inc | 939 | $242.6K | 0.00% | +16+1.7% | Added |
| Private Advisor Group, LLC | 947 | $244.6K | 0.00% | +947 | New |
| NLB Skladi, upravljanje premozenja, d.o.o. | 955 | $246.7K | 0.01% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 965 | $249.3K | 0.00% | +965 | New |
| Sequoia Financial Advisors, LLC | 993 | $256.5K | 0.00% | −90−8.3% | Reduced |
| D. E. Shaw & Co., Inc. | 996 | $257.3K | 0.00% | −1,112−52.8% | Reduced |
| Farallon Capital Management, L.L.C. | 1,000 | $258.3K | 0.00% | −1,000−50.0% | Reduced |
| Welch Group, LLC | 1,000 | $258.3K | 0.01% | +1,000 | New |
| MAI Capital Management | 1,010 | $260.9K | 0.00% | +726+255.6% | Added |
| Fifth Third Wealth Advisors LLC | 1,019 | $263.2K | 0.01% | +1,019 | New |
| Hohimer Wealth Management, LLC | 1,034 | $267.1K | 0.03% | −180−14.8% | Reduced |
| Royal Bank of Canada | 1,033 | $268.0K | 0.00% | −468−31.2% | Reduced |
| Mariner, LLC | 1,048 | $270.5K | 0.00% | −3,272−75.7% | Reduced |
| Linden Thomas Advisory Services, LLC | 1,072 | $276.9K | 0.03% | +1,072 | New |
| Toroso Investments, LLC | 1,088 | $281.1K | 0.00% | +1,088 | New |
| Evergreen Capital Management LLC | 1,094 | $282.6K | 0.01% | +8+0.7% | Added |
| GTS Securities LLC | 1,108 | $286.2K | 0.01% | +1,108 | New |
| Mount Yale Investment Advisors, LLC | 1,130 | $291.9K | 0.01% | +1,130 | New |
| Squarepoint Ops LLC | 1,138 | $294.0K | 0.00% | +1,138 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,147 | $296.3K | 0.00% | −28−2.4% | Reduced |
| Truist Financial Corp | 1,164 | $300.7K | 0.00% | +84+7.8% | Added |
| Ethic Inc. | 1,166 | $301.2K | 0.00% | +203+21.1% | Added |
| Captrust Financial Advisors | 1,179 | $304.6K | 0.00% | +4+0.3% | Added |
| New Age Alpha Advisors, LLC | 1,202 | $310.5K | 0.01% | −18−1.5% | Reduced |
| Argent Trust Co | 1,261 | $325.7K | 0.01% | 00.0% | Unchanged |
| CIBC Bancorp USA Inc. | 1,265 | $326.8K | 0.00% | +1,265 | New |
| QRG Capital Management, Inc. | 1,281 | $330.9K | 0.00% | +1,281 | New |
| Hudson Bay Capital Management LP | 1,300 | $335.8K | 0.00% | +1,300 | New |
| Hidden Cove Wealth Management, LLC | 1,302 | $336.3K | 0.22% | +443+51.6% | Added |
| Net Worth Advisory Group | 1,307 | $337.6K | 0.07% | +384+41.6% | Added |
| Vestcor Inc | 1,311 | $339.0K | 0.01% | +1,311 | New |
| Gotham Asset Management, LLC | 1,323 | $341.8K | 0.00% | +20+1.5% | Added |
| Vise Technologies, Inc. | 1,424 | $351.1K | 0.01% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 1,369 | $353.6K | 0.00% | 00.0% | Unchanged |
| Kingswood Wealth Advisors, LLC | 1,390 | $359.1K | 0.02% | +1,390 | New |
| Mindset Wealth Management, LLC | 1,450 | $374.6K | 0.10% | −343−19.1% | Reduced |
| Stratos Wealth Partners, LTD. | 1,459 | $376.9K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 1,488 | $384.4K | 0.00% | −20−1.3% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 1,525 | $393.9K | 0.00% | +116+8.2% | Added |
| IMC-Chicago, LLC | 1,591 | $411.0K | 0.01% | +1,591 | New |
| Sound View Wealth Advisors Group, LLC | 1,594 | $411.8K | 0.03% | +15+0.9% | Added |
| Vident Advisory, LLC | 1,614 | $416.9K | 0.00% | +120+8.0% | Added |
| Cynosure Management, LLC | 1,649 | $426.0K | 0.05% | −757−31.5% | Reduced |
| Parallel Advisors, LLC | 1,688 | $436.0K | 0.01% | +8+0.5% | Added |
| Aviva PLC | 1,691 | $436.8K | 0.00% | −537−24.1% | Reduced |
| Optimize Financial Inc | 1,710 | $441.7K | 0.22% | −1,145−40.1% | Reduced |
| Natixis | 1,736 | $448.4K | 0.00% | −1,184−40.5% | Reduced |
| LPL Financial LLC | 1,765 | $455.9K | 0.00% | +611+52.9% | Added |
| O'Shaughnessy Asset Management, LLC | 1,823 | $470.9K | 0.00% | −600−24.8% | Reduced |
| HighVista Strategies LLC | 1,824 | $471.2K | 0.13% | +1,824 | New |
| Measured Wealth Private Client Group, LLC | 1,826 | $471.7K | 0.13% | +1,826 | New |
| Bokf, NA | 1,829 | $472.5K | 0.01% | +1,829 | New |
| Allianz Asset Management GmbH | 1,900 | $490.8K | 0.00% | 00.0% | Unchanged |
| AlphaCentric Advisors LLC | 1,918 | $495.5K | 0.49% | +105+5.8% | Added |
| The PNC Financial Services Group, Inc. | 1,985 | $512.8K | 0.00% | +289+17.0% | Added |
| Yorktown Management & Research Co Inc | 2,000 | $516.6K | 0.43% | 00.0% | Unchanged |
| Alps Advisors Inc | 2,000 | $516.6K | 0.00% | +2,000 | New |
| HighTower Advisors, LLC | 2,049 | $529.3K | 0.00% | +937+84.3% | Added |
| Ameritas Investment Partners, Inc. | 2,055 | $530.8K | 0.02% | +42+2.1% | Added |
| Ballentine Partners, LLC | 2,115 | $546.3K | 0.01% | +7+0.3% | Added |
| Vontobel Holding Ltd. | 2,118 | $547.1K | 0.00% | −37−1.7% | Reduced |
| Swiss Life Asset Management Ltd | 2,165 | $559.3K | 0.00% | +1,174+118.5% | Added |
| Los Angeles Capital Management LLC | 2,171 | $560.8K | 0.00% | 00.0% | Unchanged |
| Janney Montgomery Scott LLC | 2,170 | $561.0K | 0.00% | −228−9.5% | Reduced |
| Entropy Technologies, LP | 2,200 | $568.3K | 0.03% | −303−12.1% | Reduced |
| Pathstone Holdings, LLC | 2,241 | $578.9K | 0.00% | −40−1.8% | Reduced |
| Blackstone Group Inc. | 2,246 | $580.2K | 0.00% | +2,246 | New |
| Empowered Funds, LLC | 2,276 | $587.9K | 0.00% | +2,276 | New |
| E Fund Management Co., Ltd. | 2,281 | $589.2K | 0.02% | +2,281 | New |
| Crossmark Global Holdings, Inc. | 2,294 | $592.6K | 0.01% | +170+8.0% | Added |
| Tower Research Capital LLC (TRC) | 2,318 | $598.8K | 0.02% | +632+37.5% | Added |
| Xponance, Inc. | 2,339 | $604.2K | 0.00% | +380+19.4% | Added |
| Public Employees Retirement Association of Colorado | 2,363 | $610.0K | 0.00% | 00.0% | Unchanged |
| Blair William & Co | 2,448 | $632.4K | 0.00% | −729−22.9% | Reduced |
| Allspring Global Investments Holdings, LLC | 2,475 | $640.8K | 0.00% | +241+10.8% | Added |
| Transcend Wealth Collective, LLC | 2,511 | $648.6K | 0.05% | +831+49.5% | Added |
| Pacer Advisors, Inc. | 2,547 | $658.0K | 0.00% | +835+48.8% | Added |
| American Century Companies Inc | 2,717 | $701.9K | 0.00% | +2,717 | New |
| Citadel Advisors LLC | 2,726 | $704.2K | 0.00% | −383,779−99.3% | Reduced |
| Teacher Retirement System of Texas | 2,823 | $729.2K | 0.00% | −399−12.4% | Reduced |
| Cinctive Capital Management LP | 2,874 | $742.4K | 0.05% | +2,874 | New |
| Freestone Grove Partners LP | 2,922 | $754.8K | 0.01% | +2,922 | New |
| Confluence Wealth Services, Inc. | 2,922 | $754.8K | 0.03% | 00.0% | Unchanged |
| Hanseatic Management Services Inc | 2,997 | $774.2K | 0.74% | +2,997 | New |
| JustInvest LLC | 3,027 | $781.9K | 0.01% | +900+42.3% | Added |
| DnB Asset Management AS | 3,100 | $800.8K | 0.00% | +7+0.2% | Added |
| Assetmark, Inc | 3,157 | $815.5K | 0.00% | +3,157 | New |
| Bank of Montreal | 3,162 | $816.8K | 0.00% | +931+41.7% | Added |
| CI Private Wealth, LLC | 3,523 | $818.5K | 0.00% | −34,823−90.8% | Reduced |
| Quantinno Capital Management LP | 3,171 | $819.1K | 0.00% | +267+9.2% | Added |
| Quadrature Capital Ltd | 3,189 | $823.8K | 0.01% | +3,189 | New |
| Resona Asset Management Co.,Ltd. | 3,194 | $825.1K | 0.00% | +137+4.5% | Added |
| Ellsworth Advisors, LLC | 3,245 | $838.2K | 0.16% | +3,245 | New |
| Virtus Investment Advisers, Inc. | 3,449 | $890.9K | 0.25% | +657+23.5% | Added |
| Pier 88 Investment Partners LLC | 3,500 | $904.1K | 0.23% | −470−11.8% | Reduced |