Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Krystal Biotech, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 284
- +15 vs. Q2 2025
- Shares held
- 28.0M
- +649.0K (+2.4%) vs. Q2 2025
- Total value
- $4.94B
- +$1.18B (+31.5%) vs. Q2 2025
- New holders
- 46
- 106 more added
- Sold out
- 31
- 86 more reduced
6 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Yorktown Management & Research Co Inc | 2,000 | $353.1K | 0.28% | +2,000 | New |
| Sound View Wealth Advisors Group, LLC | 2,003 | $353.6K | 0.02% | +56+2.9% | Added |
| JustInvest LLC | 2,011 | $355.0K | 0.00% | +316+18.6% | Added |
| Freestone Grove Partners LP | 2,031 | $358.5K | 0.00% | +136+7.2% | Added |
| Crossmark Global Holdings, Inc. | 2,069 | $365.2K | 0.01% | −388−15.8% | Reduced |
| Ameritas Investment Partners, Inc. | 2,072 | $365.8K | 0.01% | −437−17.4% | Reduced |
| Allspring Global Investments Holdings, LLC | 2,049 | $368.0K | 0.00% | −19−0.9% | Reduced |
| Man Group plc | 2,088 | $368.6K | 0.00% | −28,393−93.1% | Reduced |
| Ballentine Partners, LLC | 2,115 | $373.4K | 0.01% | 00.0% | Unchanged |
| Wolverine Trading, LLC | 2,154 | $380.7K | 0.01% | +2,154 | New |
| Quantinno Capital Management LP | 2,162 | $381.7K | 0.00% | +2,162 | New |
| Bank of Montreal | 2,329 | $411.1K | 0.00% | −2,078−47.2% | Reduced |
| DnB Asset Management AS | 2,356 | $415.9K | 0.00% | +625+36.1% | Added |
| Public Employees Retirement Association of Colorado | 2,363 | $417.0K | 0.00% | 00.0% | Unchanged |
| Advantage Alpha Capital Partners LP | 2,387 | $421.4K | 0.13% | −507−17.5% | Reduced |
| Janney Montgomery Scott LLC | 2,580 | $455.0K | 0.00% | +240+10.3% | Added |
| CIBC Bancorp USA Inc. | 2,643 | $466.6K | 0.00% | +2,643 | New |
| Optimize Financial Inc | 2,815 | $496.9K | 0.26% | +2,815 | New |
| Sig Brokerage, LP | 2,849 | $502.9K | 0.13% | +2,849 | New |
| Confluence Wealth Services, Inc. | 2,922 | $515.8K | 0.03% | 00.0% | Unchanged |
| Resona Asset Management Co.,Ltd. | 3,057 | $539.7K | 0.00% | +140+4.8% | Added |
| Virtus Investment Advisers, Inc. | 3,167 | $559.1K | 0.16% | 00.0% | Unchanged |
| Vontobel Holding Ltd. | 3,178 | $561.0K | 0.00% | +103+3.3% | Added |
| Aviva PLC | 3,231 | $570.4K | 0.00% | −344−9.6% | Reduced |
| SG Americas Securities, LLC | 3,318 | $586.0K | 0.00% | −9,289−73.7% | Reduced |
| Jane Street Group, LLC | 3,381 | $596.8K | 0.00% | +3,381 | New |
| CenterBook Partners LP | 3,429 | $605.3K | 0.03% | −1,622−32.1% | Reduced |
| Maryland State Retirement & Pension System | 3,705 | $654.0K | 0.01% | −3,769−50.4% | Reduced |
| Legato Capital Management LLC | 3,757 | $663.2K | 0.07% | +3,757 | New |
| Susquehanna Portfolio Strategies, LLC | 3,779 | $667.1K | 0.01% | +240+6.8% | Added |
| Pier 88 Investment Partners LLC | 3,820 | $674.3K | 0.13% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3,864 | $682.1K | 0.00% | 00.0% | Unchanged |
| Omers Administration Corp | 4,000 | $706.1K | 0.01% | +4,000 | New |
| Guggenheim Capital LLC | 4,052 | $715.3K | 0.01% | −2,010−33.2% | Reduced |
| Regal Investment Advisors LLC | 4,316 | $761.9K | 0.05% | −118−2.7% | Reduced |
| Pathstone Holdings, LLC | 4,347 | $767.4K | 0.00% | +408+10.4% | Added |
| Ensign Peak Advisors, Inc | 4,419 | $780.1K | 0.00% | −2,150−32.7% | Reduced |
| Cetera Investment Advisers | 4,498 | $794.0K | 0.00% | +154+3.5% | Added |
| Martingale Asset Management L P | 4,505 | $795.3K | 0.02% | 00.0% | Unchanged |
| Mariner, LLC | 4,605 | $812.9K | 0.00% | +350+8.2% | Added |
| Amundi | 4,561 | $823.6K | 0.00% | +367+8.8% | Added |
| KLP Kapitalforvaltning AS | 4,700 | $829.7K | 0.00% | +400+9.3% | Added |
| Blair William & Co | 4,752 | $838.9K | 0.00% | −100−2.1% | Reduced |
| Polygon Management Ltd. | 4,870 | $859.7K | 0.12% | +4,870 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 5,025 | $887.1K | 0.00% | +891+21.6% | Added |
| China Universal Asset Management Co., Ltd. | 5,073 | $895.5K | 0.07% | −731−12.6% | Reduced |
| Teacher Retirement System of Texas | 5,331 | $941.1K | 0.00% | −510−8.7% | Reduced |
| Cookson Peirce & Co Inc | 5,654 | $998.1K | 0.04% | +5,654 | New |
| ProShare Advisors LLC | 5,717 | $1.01M | 0.00% | −908−13.7% | Reduced |
| State Board of Administration of Florida Retirement System | 5,785 | $1.02M | 0.00% | −22−0.4% | Reduced |
| Oregon Public Employees Retirement Fund | 5,839 | $1.03M | 0.01% | +37+0.6% | Added |
| Dark Forest Capital Management LP | 5,903 | $1.04M | 0.04% | +399+7.2% | Added |
| Cynosure Management, LLC | 5,918 | $1.04M | 0.11% | 00.0% | Unchanged |
| Arizona State Retirement System | 6,397 | $1.13M | 0.01% | +81+1.3% | Added |
| Summit Trail Advisors, LLC | 6,464 | $1.14M | 0.02% | −36−0.6% | Reduced |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 6,560 | $1.16M | 0.01% | +31+0.5% | Added |
| Los Angeles Capital Management LLC | 6,757 | $1.19M | 0.00% | −19,881−74.6% | Reduced |
| D. E. Shaw & Co., Inc. | 6,814 | $1.20M | 0.00% | −4,913−41.9% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 6,859 | $1.21M | 0.01% | +1,259+22.5% | Added |
| Comerica Bank | 7,151 | $1.26M | 0.00% | −1,557−17.9% | Reduced |
| Quantum Private Wealth, LLC | 7,205 | $1.27M | 0.37% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 7,220 | $1.27M | 0.01% | −1,109−13.3% | Reduced |
| STRS Ohio | 7,400 | $1.31M | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 7,416 | $1.31M | 0.01% | +190+2.6% | Added |
| Tealwood Asset Management Inc | 7,902 | $1.40M | 0.56% | −281−3.4% | Reduced |
| Winton Group Ltd | 8,212 | $1.45M | 0.05% | +8,212 | New |
| Yousif Capital Management, LLC | 8,217 | $1.45M | 0.02% | −1,383−14.4% | Reduced |
| Profund Advisors LLC | 8,330 | $1.47M | 0.05% | +164+2.0% | Added |
| NFJ Investment Group, LLC | 8,612 | $1.52M | 0.05% | +8,612 | New |
| Boothbay Fund Management, LLC | 8,889 | $1.57M | 0.04% | +8,889 | New |
| Perigon Wealth Management, LLC | 8,929 | $1.58M | 0.03% | +31+0.3% | Added |
| BNP Paribas Arbitrage, SA | 9,179 | $1.62M | 0.00% | +1,996+27.8% | Added |
| Citigroup Inc | 9,650 | $1.70M | 0.00% | −42,883−81.6% | Reduced |
| Bridgewater Associates, LP | 9,723 | $1.72M | 0.01% | +9,723 | New |
| Intech Investment Management LLC | 9,751 | $1.72M | 0.02% | −1,227−11.2% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 9,778 | $1.73M | 0.01% | +9,778 | New |
| Commonwealth Equity Services, LLC | 10,006 | $1.77M | 0.00% | +1,791+21.8% | Added |
| Janus Henderson Group PLC | 10,071 | $1.78M | 0.00% | 00.0% | Unchanged |
| Main Management ETF Advisors, LLC | 10,075 | $1.78M | 0.07% | +4,944+96.4% | Added |
| Schroder Investment Management Group | 10,170 | $1.80M | 0.00% | −58−0.6% | Reduced |
| GW&K Investment Management, LLC | 10,492 | $1.85M | 0.02% | −19,683−65.2% | Reduced |
| Acuta Capital Partners, LLC | 10,573 | $1.87M | 1.93% | +10,573 | New |
| Wellington Management Group LLP | 10,881 | $1.92M | 0.00% | +728+7.2% | Added |
| State of Tennessee, Treasury Department | 11,118 | $1.96M | 0.01% | +167+1.5% | Added |
| Creative Planning | 11,609 | $2.05M | 0.00% | +3,253+38.9% | Added |
| Rhenman & Partners Asset Management AB | 11,750 | $2.07M | 0.23% | −1,000−7.8% | Reduced |
| Louisiana State Employees Retirement System | 11,800 | $2.08M | 0.03% | −100−0.8% | Reduced |
| Torray LLC | 11,901 | $2.10M | 0.29% | +327+2.8% | Added |
| Privium Fund Management B.V. | 12,170 | $2.15M | 0.39% | +2,850+30.6% | Added |
| Evolutionary Tree Capital Management, LLC | 12,461 | $2.20M | 2.40% | +165+1.3% | Added |
| Envestnet Asset Management Inc | 13,108 | $2.31M | 0.00% | −2,008−13.3% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 13,290 | $2.35M | 0.00% | −1,993−13.0% | Reduced |
| Alps Advisors Inc | 13,367 | $2.36M | 0.01% | −4,095−23.5% | Reduced |
| Bridge City Capital, LLC | 14,154 | $2.50M | 0.67% | +14,154 | New |
| Illinois Municipal Retirement Fund | 14,245 | $2.51M | 0.03% | +1,934+15.7% | Added |
| State of Alaska, Department of Revenue | 14,274 | $2.52M | 0.03% | −856−5.7% | Reduced |
| MetLife Investment Management | 14,430 | $2.55M | 0.01% | −316−2.1% | Reduced |
| State of New Jersey Common Pension Fund D | 14,599 | $2.58M | 0.01% | −434−2.9% | Reduced |
| Fieldview Capital Management, LLC | 14,705 | $2.60M | 0.42% | +159+1.1% | Added |
| Fiera Capital Corp | 15,063 | $2.66M | 0.01% | −448−2.9% | Reduced |