Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 275
- −21 vs. Q1 2025
- Shares held
- 27.7M
- +56.6K (+0.2%) vs. Q1 2025
- Total value
- $3.80B
- −$1.17B (−23.6%) vs. Q1 2025
- New holders
- 42
- 101 more added
- Sold out
- 63
- 96 more reduced
3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Tempus Wealth Planning, LLC | 2,379 | $327.0K | 0.08% | +2,379 | New |
| Graham Capital Management, L.P. | 2,435 | $334.7K | 0.01% | +256+11.7% | Added |
| Crossmark Global Holdings, Inc. | 2,457 | $337.7K | 0.01% | +87+3.7% | Added |
| Ameritas Investment Partners, Inc. | 2,509 | $344.9K | 0.01% | 00.0% | Unchanged |
| EP Wealth Advisors, LLC | 2,726 | $374.7K | 0.00% | +105+4.0% | Added |
| Advantage Alpha Capital Partners LP | 2,894 | $397.8K | 0.11% | −675−18.9% | Reduced |
| Resona Asset Management Co.,Ltd. | 2,917 | $401.0K | 0.00% | +2,917 | New |
| Confluence Wealth Services, Inc. | 2,922 | $401.7K | 0.02% | +2+0.1% | Added |
| Tower Research Capital LLC (TRC) | 2,998 | $412.1K | 0.01% | +2,268+310.7% | Added |
| CIBC World Markets Corp | 3,055 | $419.9K | 0.00% | −2,449−44.5% | Reduced |
| Vontobel Holding Ltd. | 3,075 | $422.7K | 0.00% | +375+13.9% | Added |
| Virtus Investment Advisers, Inc. | 3,167 | $435.3K | 0.15% | +1,099+53.1% | Added |
| Hennion & Walsh Asset Management, Inc. | 3,253 | $447.2K | 0.02% | −6,952−68.1% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 3,539 | $486.5K | 0.01% | +3,539 | New |
| Aviva PLC | 3,575 | $491.4K | 0.00% | +319+9.8% | Added |
| M&T Bank Corp | 3,785 | $520.4K | 0.00% | +85+2.3% | Added |
| Pier 88 Investment Partners LLC | 3,820 | $525.1K | 0.10% | −610−13.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3,864 | $531.1K | 0.00% | −1,878−32.7% | Reduced |
| E Fund Management Co., Ltd. | 3,870 | $532.0K | 0.03% | +1,612+71.4% | Added |
| Pathstone Holdings, LLC | 3,939 | $541.5K | 0.00% | −4,170−51.4% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 4,134 | $568.3K | 0.00% | −8,619−67.6% | Reduced |
| Mariner, LLC | 4,255 | $584.9K | 0.00% | +618+17.0% | Added |
| KLP Kapitalforvaltning AS | 4,300 | $591.1K | 0.00% | 00.0% | Unchanged |
| Amundi | 4,194 | $592.8K | 0.00% | +4,194 | New |
| Bryce Point Capital, LLC | 4,323 | $594.2K | 0.50% | +37+0.9% | Added |
| Cetera Investment Advisers | 4,344 | $597.1K | 0.00% | +2,255+107.9% | Added |
| Bank of Montreal | 4,407 | $605.8K | 0.00% | −11−0.2% | Reduced |
| Regal Investment Advisors LLC | 4,434 | $609.5K | 0.05% | +127+2.9% | Added |
| Martingale Asset Management L P | 4,505 | $619.3K | 0.02% | −631−12.3% | Reduced |
| Summit Global Investments | 4,547 | $625.0K | 0.04% | −164−3.5% | Reduced |
| Blair William & Co | 4,852 | $667.0K | 0.00% | −4,581−48.6% | Reduced |
| CenterBook Partners LP | 5,051 | $694.3K | 0.04% | +5,051 | New |
| Main Management ETF Advisors, LLC | 5,131 | $705.0K | 0.03% | +84+1.7% | Added |
| Dark Forest Capital Management LP | 5,504 | $756.6K | 0.03% | −3,933−41.7% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 5,600 | $769.8K | 0.01% | +180+3.3% | Added |
| Oregon Public Employees Retirement Fund | 5,802 | $797.5K | 0.01% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 5,804 | $797.8K | 0.08% | +26+0.4% | Added |
| State Board of Administration of Florida Retirement System | 5,807 | $798.2K | 0.00% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 5,841 | $802.9K | 0.00% | +36+0.6% | Added |
| Cynosure Management, LLC | 5,918 | $813.5K | 0.09% | +2,016+51.7% | Added |
| Guggenheim Capital LLC | 6,062 | $833.3K | 0.01% | +1,909+46.0% | Added |
| Arizona State Retirement System | 6,316 | $868.2K | 0.01% | +145+2.3% | Added |
| Summit Trail Advisors, LLC | 6,500 | $893.5K | 0.02% | +6,500 | New |
| Shay Capital LLC | 6,500 | $893.5K | 0.20% | +6,500 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 6,529 | $897.5K | 0.00% | +472+7.8% | Added |
| Ensign Peak Advisors, Inc | 6,569 | $903.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 6,625 | $910.7K | 0.00% | −526−7.4% | Reduced |
| M&G Plc | 6,748 | $924.5K | 0.01% | +6,748 | New |
| BNP Paribas Arbitrage, SA | 7,183 | $987.4K | 0.00% | +2,746+61.9% | Added |
| Quantum Private Wealth, LLC | 7,205 | $990.4K | 0.32% | 00.0% | Unchanged |
| Amalgamated Bank | 7,226 | $993.0K | 0.01% | +26+0.4% | Added |
| Sphera Funds Management Ltd. | 7,335 | $1.01M | 0.26% | +7,335 | New |
| STRS Ohio | 7,400 | $1.02M | 0.00% | +500+7.2% | Added |
| Maryland State Retirement & Pension System | 7,474 | $1.03M | 0.02% | +123+1.7% | Added |
| Virginia Retirement Systems Et Al | 7,800 | $1.07M | 0.01% | 00.0% | Unchanged |
| Profund Advisors LLC | 8,166 | $1.12M | 0.04% | +2,203+36.9% | Added |
| Tealwood Asset Management Inc | 8,183 | $1.13M | 0.50% | +8,183 | New |
| Commonwealth Equity Services, LLC | 8,215 | $1.13M | 0.00% | +912+12.5% | Added |
| Teachers Retirement System of the State of Kentucky | 8,329 | $1.15M | 0.01% | −681−7.6% | Reduced |
| Creative Planning | 8,356 | $1.15M | 0.00% | −3,730−30.9% | Reduced |
| Comerica Bank | 8,708 | $1.20M | 0.00% | +7+0.1% | Added |
| Perigon Wealth Management, LLC | 8,898 | $1.22M | 0.03% | +407+4.8% | Added |
| OrbiMed Advisors LLC | 9,200 | $1.26M | 0.03% | −14,300−60.9% | Reduced |
| Privium Fund Management B.V. | 9,320 | $1.30M | 0.28% | +1,810+24.1% | Added |
| Yousif Capital Management, LLC | 9,600 | $1.32M | 0.01% | +30+0.3% | Added |
| Janus Henderson Group PLC | 10,071 | $1.38M | 0.00% | 00.0% | Unchanged |
| Wellington Management Group LLP | 10,153 | $1.40M | 0.00% | −446−4.2% | Reduced |
| Schroder Investment Management Group | 10,228 | $1.41M | 0.00% | −2,820−21.6% | Reduced |
| Russell Investments Group, Ltd. | 10,358 | $1.42M | 0.00% | −27,423−72.6% | Reduced |
| State of Tennessee, Treasury Department | 10,951 | $1.51M | 0.01% | −211−1.9% | Reduced |
| Intech Investment Management LLC | 10,978 | $1.51M | 0.01% | −1,100−9.1% | Reduced |
| Torray LLC | 11,574 | $1.59M | 0.23% | +11,574 | New |
| D. E. Shaw & Co., Inc. | 11,727 | $1.61M | 0.00% | −38,165−76.5% | Reduced |
| Louisiana State Employees Retirement System | 11,900 | $1.64M | 0.03% | 00.0% | Unchanged |
| AQR Capital Management LLC | 11,968 | $1.65M | 0.00% | −163−1.3% | Reduced |
| Evolutionary Tree Capital Management, LLC | 12,296 | $1.69M | 1.79% | −1,047−7.8% | Reduced |
| Illinois Municipal Retirement Fund | 12,311 | $1.69M | 0.02% | −451−3.5% | Reduced |
| Millennium Management LLC | 12,562 | $1.73M | 0.00% | −47,826−79.2% | Reduced |
| SG Americas Securities, LLC | 12,607 | $1.73M | 0.01% | +11,295+860.9% | Added |
| Rhenman & Partners Asset Management AB | 12,750 | $1.75M | 0.22% | −5,000−28.2% | Reduced |
| Fieldview Capital Management, LLC | 14,546 | $2.00M | 0.30% | −1,796−11.0% | Reduced |
| MetLife Investment Management | 14,746 | $2.03M | 0.01% | +222+1.5% | Added |
| State of New Jersey Common Pension Fund D | 15,033 | $2.07M | 0.01% | +4,682+45.2% | Added |
| Envestnet Asset Management Inc | 15,116 | $2.08M | 0.00% | +2,717+21.9% | Added |
| State of Alaska, Department of Revenue | 15,130 | $2.08M | 0.02% | +1,106+7.9% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 15,283 | $2.10M | 0.00% | −610−3.8% | Reduced |
| Fiera Capital Corp | 15,511 | $2.13M | 0.01% | −134−0.9% | Reduced |
| DekaBank Deutsche Girozentrale | 15,503 | $2.15M | 0.00% | 00.0% | Unchanged |
| New York State Teachers Retirement System | 15,650 | $2.15M | 0.00% | −329−2.1% | Reduced |
| Wells Fargo & Company | 16,547 | $2.27M | 0.00% | −588−3.4% | Reduced |
| Alps Advisors Inc | 17,462 | $2.40M | 0.01% | +15,542+809.5% | Added |
| Erste Asset Management GmbH | 18,200 | $2.53M | 0.02% | 00.0% | Unchanged |
| Franklin Resources Inc | 18,425 | $2.53M | 0.00% | −588−3.1% | Reduced |
| Thrivent Financial for Lutherans | 18,700 | $2.57M | 0.01% | +110+0.6% | Added |
| Deutsche Bank AG | 19,135 | $2.63M | 0.00% | −2,602−12.0% | Reduced |
| SEI Investments Co | 19,300 | $2.65M | 0.00% | +609+3.3% | Added |
| Edgestream Partners, L.P. | 19,678 | $2.70M | 0.08% | +19,678 | New |
| TD Asset Management Inc | 20,080 | $2.76M | 0.00% | −20,188−50.1% | Reduced |
| California State Teachers Retirement System | 20,126 | $2.77M | 0.00% | 00.0% | Unchanged |
| HealthInvest Partners AB | 20,158 | $2.77M | 1.19% | −3,333−14.2% | Reduced |