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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Krystal Biotech, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
299
+37 vs. Q4 2024
Shares held
27.6M
+139.0K (+0.5%) vs. Q4 2024
Total value
$4.98B
+$673.8M (+15.7%) vs. Q4 2024
New holders
64
88 more added
Sold out
27
112 more reduced

2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 299 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ1 2025: $4.98B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q4 2024.

Institutions holding KRYS in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Virtus Investment Advisers, Inc.2,068$372.9K0.10%+2,068New
Cetera Investment Advisers2,089$376.6K0.00%−87−4.0%Reduced
Ballentine Partners, LLC2,136$385.1K0.01%−9−0.4%Reduced
The PNC Financial Services Group, Inc.2,141$386.0K0.00%+461+27.4%Added
Graham Capital Management, L.P.2,179$392.9K0.01%+97+4.7%Added
Susquehanna Fundamental Investments, LLC2,242$404.2K0.01%+2,242New
E Fund Management Co., Ltd.2,258$407.1K0.02%+324+16.8%Added
Entropy Technologies, LP2,300$414.7K0.04%−1,200−34.3%Reduced
Fox Run Management, L.L.C.2,354$424.4K0.07%+193+8.9%Added
Public Employees Retirement Association of Colorado2,363$426.0K0.00%00.0%Unchanged
Crossmark Global Holdings, Inc.2,370$427.3K0.01%+63+2.7%Added
Ameritas Investment Partners, Inc.2,509$452.4K0.02%−86−3.3%Reduced
Connor, Clark & Lunn Investment Management Ltd.2,582$465.5K0.00%+2,582New
Camden Capital, LLC2,585$466.1K0.05%+1,220+89.4%Added
EP Wealth Advisors, LLC2,621$472.6K0.00%+2,621New
Bellevue Group AG2,650$477.8K0.01%−2,397−47.5%Reduced
Confluence Wealth Services, Inc.2,920$484.1K0.03%00.0%Unchanged
Vontobel Holding Ltd.2,700$486.8K0.00%−284−9.5%Reduced
Scientech Research LLC2,737$493.5K0.13%+2,737New
Aster Capital Management (DIFC) Ltd2,776$497.6K0.09%+2,776New
Vident Advisory, LLC2,787$502.5K0.01%+295+11.8%Added
HSBC Holdings PLC2,875$507.9K0.00%−1,644−36.4%Reduced
Jump Financial, LLC2,983$537.8K0.01%+2,983New
Aviva PLC3,256$587.1K0.00%+3,256New
Jain Global LLC3,442$620.6K0.01%−1,358−28.3%Reduced
Advantage Alpha Capital Partners LP3,569$643.5K0.16%+3,569New
Roman Butler Fullerton & Co3,867$654.0K0.25%+3,867New
Mariner, LLC3,637$655.8K0.00%+262+7.8%Added
M&T Bank Corp3,700$667.2K0.00%+3,700New
Allianz Asset Management GmbH3,715$669.8K0.00%−387−9.4%Reduced
Fred Alger Management, LLC3,728$672.2K0.00%+3,728New
Quadrant Capital Group LLC3,883$700.1K0.03%+3,726+2,373.2%Added
Cynosure Management, LLC3,902$703.5K0.10%+272+7.5%Added
Guggenheim Capital LLC4,153$748.8K0.01%−709−14.6%Reduced
Jefferies Financial Group Inc.4,200$757.3K0.01%+4,200New
KLP Kapitalforvaltning AS4,300$775.3K0.00%00.0%Unchanged
Regal Investment Advisors LLC4,307$776.6K0.06%+4,307New
Bryce Point Capital, LLC4,286$789.7K0.59%+4,286New
Eschler Asset Management LLP4,403$793.9K2.01%+4,403New
Bank of Montreal4,418$796.6K0.00%+1,093+32.9%Added
Pier 88 Investment Partners LLC4,430$798.7K0.15%+680+18.1%Added
BNP Paribas Arbitrage, SA4,437$800.0K0.00%−3,352−43.0%Reduced
Prime Capital Investment Advisors, LLC4,504$812.1K0.01%+4,504New
HRT Financial LP4,680$843.0K0.01%−17,327−78.7%Reduced
Summit Global Investments4,711$849.0K0.06%+1,258+36.4%Added
Gotham Asset Management, LLC4,804$866.2K0.01%+4,804New
Allspring Global Investments Holdings, LLC5,180$904.3K0.00%−24,597−82.6%Reduced
Main Management ETF Advisors, LLC5,047$910.0K0.06%+1,487+41.8%Added
Martingale Asset Management L P5,136$926.0K0.02%00.0%Unchanged
Legato Capital Management LLC5,190$935.8K0.13%+5,190New
Police & Firemen's Retirement System of New Jersey5,420$977.2K0.01%+137+2.6%Added
CIBC World Markets Corp5,504$992.4K0.01%+3,183+137.1%Added
Zurcher Kantonalbank (Zurich Cantonalbank)5,742$1.04M0.00%−312−5.2%Reduced
China Universal Asset Management Co., Ltd.5,778$1.04M0.10%−320−5.2%Reduced
Oregon Public Employees Retirement Fund5,802$1.05M0.02%−173−2.9%Reduced
Teacher Retirement System of Texas5,805$1.05M0.00%−578−9.1%Reduced
State Board of Administration of Florida Retirement System5,807$1.05M0.00%00.0%Unchanged
Profund Advisors LLC5,963$1.08M0.05%−358−5.7%Reduced
Commonwealth of Pennsylvania Public School Empls Retrmt Sys6,057$1.09M0.01%+654+12.1%Added
Arizona State Retirement System6,171$1.11M0.01%−71−1.1%Reduced
Nebula Research & Development LLC6,220$1.12M0.10%+3,550+133.0%Added
Ensign Peak Advisors, Inc6,569$1.18M0.00%00.0%Unchanged
STRS Ohio6,900$1.24M0.01%−400−5.5%Reduced
ProShare Advisors LLC7,151$1.29M0.00%−1,697−19.2%Reduced
Amalgamated Bank7,200$1.30M0.01%−236−3.2%Reduced
Quantum Private Wealth, LLC7,205$1.30M0.49%00.0%Unchanged
Winton Group Ltd7,274$1.31M0.08%+709+10.8%Added
Commonwealth Equity Services, LLC7,303$1.32M0.00%+2,437+50.1%Added
Maryland State Retirement & Pension System7,351$1.33M0.03%−1,172−13.8%Reduced
Privium Fund Management B.V.7,510$1.35M0.35%−1,740−18.8%Reduced
Virginia Retirement Systems Et Al7,800$1.41M0.01%+7,800New
Jackson Creek Investment Advisors LLC8,048$1.45M0.46%−40.0%Reduced
Pathstone Holdings, LLC8,109$1.46M0.01%+3,857+90.7%Added
Perigon Wealth Management, LLC8,491$1.53M0.04%+202+2.4%Added
Comerica Bank8,701$1.57M0.01%−189−2.1%Reduced
Teachers Retirement System of the State of Kentucky9,010$1.62M0.01%00.0%Unchanged
Blair William & Co9,433$1.70M0.01%+1,990+26.7%Added
Dark Forest Capital Management LP9,437$1.70M0.08%+9,437New
Yousif Capital Management, LLC9,570$1.73M0.02%−207−2.1%Reduced
ExodusPoint Capital Management, LP9,952$1.79M0.02%+191+2.0%Added
Hennion & Walsh Asset Management, Inc.10,205$1.84M0.08%−3,473−25.4%Reduced
Janus Henderson Group PLC10,071$1.85M0.00%00.0%Unchanged
State of New Jersey Common Pension Fund D10,351$1.87M0.01%−1,452−12.3%Reduced
Wellington Management Group LLP10,599$1.91M0.00%−1,105−9.4%Reduced
State of Tennessee, Treasury Department11,162$2.01M0.01%−137−1.2%Reduced
Renaissance Technologies LLC11,200$2.02M0.00%+300+2.8%Added
Redwood Investments, LLC11,267$2.03M0.76%−76−0.7%Reduced
Louisiana State Employees Retirement System11,900$2.15M0.04%−300−2.5%Reduced
Intech Investment Management LLC12,078$2.18M0.02%+1,239+11.4%Added
Creative Planning12,086$2.18M0.00%+6,689+123.9%Added
AQR Capital Management LLC12,131$2.19M0.00%+2,792+29.9%Added
Envestnet Asset Management Inc12,399$2.24M0.00%+769+6.6%Added
Universal- Beteiligungs- und Servicegesellschaft mbH12,753$2.30M0.00%−10,444−45.0%Reduced
Illinois Municipal Retirement Fund12,762$2.30M0.03%−1,384−9.8%Reduced
Federated Hermes, Inc.12,781$2.30M0.00%−267−2.0%Reduced
Corebridge Financial, Inc.12,970$2.34M0.01%−255−1.9%Reduced
Trexquant Investment LP13,122$2.37M0.03%+13,122New
Schroder Investment Management Group13,048$2.40M0.00%+441+3.5%Added
Evolutionary Tree Capital Management, LLC13,343$2.41M2.80%+2,643+24.7%Added
State of Alaska, Department of Revenue14,024$2.53M0.03%−399−2.8%Reduced