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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Krystal Biotech, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
154
+8 vs. Q3 2022
Shares held
20.9M
+147.3K (+0.7%) vs. Q3 2022
Total value
$1.66B
+$208.7M (+14.4%) vs. Q3 2022
New holders
18
62 more added
Sold out
10
50 more reduced

2 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 154 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ4 2022: $1.66B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q3 2022.

Institutions holding KRYS in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
State of New Jersey Common Pension Fund D29,901$2.37M0.01%−3,561−10.6%Reduced
DekaBank Deutsche Girozentrale30,300$2.38M0.01%00.0%Unchanged
Rhumbline Advisers31,834$2.52M0.00%+711+2.3%Added
EAM Investors, LLC33,245$2.63M0.55%−194−0.6%Reduced
Barclays PLC36,348$2.88M0.00%+3,217+9.7%Added
CWM, LLC37,130$2.94M0.02%−6,254−14.4%Reduced
SG Americas Securities, LLC38,774$3.07M0.05%+36,434+1,557.0%Added
UBS Group AG42,623$3.38M0.00%+42,459+25,889.6%Added
Swiss National Bank43,400$3.44M0.00%+800+1.9%Added
International Biotechnology Trust PLC45,000$3.56M1.10%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.45,203$3.58M0.22%+4,547+11.2%Added
Citadel Advisors LLC52,676$4.17M0.00%+43,938+502.8%Added
Monarch Partners Asset Management LLC53,905$4.27M1.26%+7,411+15.9%Added
Nuveen Asset Management, LLC57,412$4.55M0.00%−27,913−32.7%Reduced
Silverarc Capital Management, LLC58,535$4.64M1.60%+1,890+3.3%Added
Rafferty Asset Management, LLC61,625$4.88M0.04%+9,369+17.9%Added
Voya Investment Management LLC62,609$4.96M0.01%−1,577−2.5%Reduced
Morgan Stanley66,051$5.23M0.00%+18,738+39.6%Added
Bank of America Corp68,043$5.39M0.00%+26,679+64.5%Added
Verition Fund Management LLC80,561$6.38M0.12%+12,909+19.1%Added
Bank of New York Mellon Corp82,096$6.50M0.00%−2,696−3.2%Reduced
Rubric Capital Management LP92,609$7.34M0.32%00.0%Unchanged
Handelsbanken Fonder AB105,200$8.33M0.05%+300+0.3%Added
ExodusPoint Capital Management, LP105,761$8.38M0.13%+40,975+63.2%Added
S Squared Technology, LLC108,215$8.57M5.80%00.0%Unchanged
Integral Health Asset Management, LLC115,000$9.11M2.05%+25,000+27.8%Added
Goldman Sachs Group Inc147,601$11.7M0.00%+5,216+3.7%Added
Charles Schwab Investment Management Inc160,615$12.7M0.00%+4,344+2.8%Added
Deerfield Management Company, L.P. (Series C)175,000$13.9M0.29%00.0%Unchanged
Soleus Capital Management, L.P.188,217$14.9M2.14%−19,115−9.2%Reduced
Northern Trust Corp201,288$15.9M0.00%−950−0.5%Reduced
C WorldWide Group Holding A/S225,809$17.9M0.24%00.0%Unchanged
JPMorgan Chase & Co237,937$18.8M0.00%−4,756−2.0%Reduced
Nicholas Investment Partners, LP267,089$21.2M1.85%+45,063+20.3%Added
Skandinaviska Enskilda Banken AB (publ)287,541$22.8M0.17%−10,069−3.4%Reduced
Baker Bros. Advisors LP302,716$24.0M0.14%−119,469−28.3%Reduced
Victory Capital Management Inc339,331$26.9M0.03%+35,732+11.8%Added
Braidwell LP358,056$28.4M0.95%+358,056New
Dimensional Fund Advisors LP389,285$30.8M0.01%+30,448+8.5%Added
Artal Group S.A.400,000$31.7M1.83%−100,000−20.0%Reduced
Geode Capital Management, LLC412,127$32.6M0.00%+12,865+3.2%Added
Hood River Capital Management LLC426,879$33.8M1.23%+10,123+2.4%Added
First Light Asset Management, LLC473,691$37.5M3.48%−18,864−3.8%Reduced
Point72 Asset Management, L.P.556,252$44.1M0.17%−702,253−55.8%Reduced
Pictet Asset Management SA625,979$49.6M0.07%−98,223−13.6%Reduced
Credit Suisse AG682,880$54.1M0.06%+4,410+0.6%Added
Frazier Life Sciences Management, L.P.999,737$79.2M4.92%−18,651−1.8%Reduced
State Street Corp1,038,983$82.3M0.00%+44,839+4.5%Added
Vanguard Group Inc1,188,110$94.1M0.00%+91,978+8.4%Added
Lord, Abbett & Co. LLC1,278,022$101.2M0.36%+66,081+5.5%Added
Avoro Capital Advisors LLC1,410,000$111.7M1.67%+135,000+10.6%Added
BlackRock Inc.1,699,596$134.6M0.00%+134,291+8.6%Added
Redmile Group, LLC1,896,645$150.3M6.15%−2,900−0.2%Reduced
FMR LLC2,108,853$167.1M0.02%+2,419+0.1%Added
Tudor Investment Corp Et Al0$00.00%−11,546−100.0%Sold out
Squarepoint Ops LLC0$00.00%−8,320−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−6,703−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−5,159−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−3,670−100.0%Sold out
Amundi0$00.00%−1,762−100.0%Sold out
Almanack Investment Partners, LLC.0$00.00%−732−100.0%Sold out
Macquarie Group Ltd0$00.00%−382−100.0%Sold out
AlphaMark Advisors, LLC0$00.00%−10−100.0%Sold out
SJS Investment Consulting Inc.0$00.00%−1−100.0%Sold out
ACT Capital Management, LLC––––Not filed
Wipfli Financial Advisors LLC,––––Not filed