Crescent Biopharma, Inc.
CBIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001253689
In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Crescent Biopharma, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 63
- +6 vs. Q4 2025
- Shares held
- 25.9M
- +2.39M (+10.1%) vs. Q4 2025
- Total value
- $476.6M
- +$197.4M (+70.7%) vs. Q4 2025
- New holders
- 17
- 18 more added
- Sold out
- 11
- 8 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 82 | $532.6M |
| Q1 2026 | 63 | $476.6M |
| Q4 2025 | 58 | $285.9M |
| Q3 2025 | 41 | $134.6M |
| Q2 2025 | 30 | $173.5M |
| Q1 2025 | 35 | $6.46M |
| Q4 2024 | 41 | $7.56M |
| Q3 2024 | 36 | $3.00M |
| Q2 2024 | 35 | $7.20M |
| Q1 2024 | 69 | $110.5M |
| Q4 2023 | 58 | $82.8M |
| Q3 2023 | 49 | $52.1M |
| Q2 2023 | 55 | $61.9M |
| Q1 2023 | 54 | $46.6M |
| Q4 2022 | 48 | $83.3M |
| Q3 2022 | 35 | $14.3M |
| Q2 2022 | 37 | $15.8M |
| Q1 2022 | 44 | $31.2M |
| Q4 2021 | 47 | $42.7M |
| Q3 2021 | 48 | $64.9M |
| Q2 2021 | 58 | $72.5M |
| Q1 2021 | 78 | $110.4M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FMR LLC | 4,133,514 | $75.9M | 0.00% | 00.0% | Unchanged |
| BVF Inc | 2,748,763 | $50.5M | 1.61% | 00.0% | Unchanged |
| Fairmount Funds Management LLC | 2,747,866 | $50.5M | 3.65% | 00.0% | Unchanged |
| VR Adviser, LLC | 2,133,576 | $39.2M | 1.46% | 00.0% | Unchanged |
| FCPM III Services B.V. | 1,677,852 | $30.8M | 4.27% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 1,510,033 | $27.7M | 0.05% | +1,398,318+1,251.7% | Added |
| Vestal Point Capital, LP | 1,500,000 | $27.6M | 0.77% | 00.0% | Unchanged |
| Opaleye Management Inc. | 1,312,615 | $24.1M | 3.18% | +134,315+11.4% | Added |
| Tang Capital Management LLC | 1,160,000 | $21.3M | 1.08% | +287,602+33.0% | Added |
| Vanguard Capital Management LLC | 801,395 | $14.7M | 0.00% | +801,395 | New |
| Logos Global Management LP | 482,500 | $8.86M | 0.46% | −117,500−19.6% | Reduced |
| Deep Track Capital, LP | 453,686 | $8.33M | 0.17% | 00.0% | Unchanged |
| Boxer Capital Management, LLC | 453,686 | $8.33M | 1.09% | 00.0% | Unchanged |
| RTW Investments, LP | 372,856 | $6.85M | 0.07% | 00.0% | Unchanged |
| NEXTBio Capital Management LP | 372,856 | $6.85M | 3.18% | 00.0% | Unchanged |
| Remedium Capital Partners, LLC | 361,250 | $6.64M | 2.36% | 00.0% | Unchanged |
| Millennium Management LLC | 323,553 | $5.94M | 0.00% | +261,671+422.9% | Added |
| Price T Rowe Associates Inc | 303,551 | $5.58M | 0.00% | −34,574−10.2% | Reduced |
| Point72 Asset Management, L.P. | 300,000 | $5.51M | 0.01% | 00.0% | Unchanged |
| Alyeska Investment Group, L.P. | 264,000 | $4.85M | 0.01% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 228,475 | $4.20M | 0.00% | +203,230+805.0% | Added |
| Susquehanna International Group, LLP | 213,635 | $3.92M | 0.01% | +156,587+274.5% | Added |
| Perceptive Advisors LLC | 206,942 | $3.80M | 0.08% | −246,744−54.4% | Reduced |
| Marshall Wace, LLP | 200,780 | $3.69M | 0.00% | +178,954+819.9% | Added |
| Exome Asset Management LLC | 153,191 | $2.81M | 1.66% | +153,191 | New |
| Jennison Associates LLC | 152,974 | $2.81M | 0.00% | +152,974 | New |
| Silverarc Capital Management, LLC | 130,500 | $2.40M | 0.28% | +130,500 | New |
| Two Sigma Investments, LP | 115,828 | $2.13M | 0.00% | −9,396−7.5% | Reduced |
| BlackRock, Inc. | 115,725 | $2.13M | 0.00% | +6,495+5.9% | Added |
| Geode Capital Management, LLC | 104,221 | $1.92M | 0.00% | +13,142+14.4% | Added |
| Hudson Bay Capital Management LP | 88,867 | $1.63M | 0.01% | +88,867 | New |
| Stonepine Capital Management, LLC | 85,000 | $1.56M | 1.37% | −2,682−3.1% | Reduced |
| UBS Group AG | 82,706 | $1.52M | 0.00% | +75,581+1,060.8% | Added |
| Woodline Partners LP | 74,000 | $1.36M | 0.01% | 00.0% | Unchanged |
| Burkehill Global Management, LP | 74,000 | $1.36M | 0.07% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 50,273 | $923.5K | 0.06% | −555,727−91.7% | Reduced |
| Vanguard Fiduciary Trust Co | 49,423 | $907.9K | 0.00% | +49,423 | New |
| State Street Corp | 39,067 | $717.7K | 0.00% | +12,850+49.0% | Added |
| JPMorgan Chase & Co | 41,004 | $681.5K | 0.00% | +17,665+75.7% | Added |
| Barclays PLC | 30,189 | $554.6K | 0.00% | +30,189 | New |
| Bank of America Corp | 29,277 | $537.8K | 0.00% | +23,704+425.3% | Added |
| Moore Capital Management, LP | 25,000 | $459.3K | 0.02% | 00.0% | Unchanged |
| Lighthouse Investment Partners, LLC | 25,000 | $459.3K | 0.02% | +25,000 | New |
| Manufacturers Life Insurance Company, The | 24,903 | $457.5K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 24,262 | $445.7K | 0.00% | −22,438−48.0% | Reduced |
| Quadrature Capital Ltd | 20,917 | $384.2K | 0.00% | +7,671+57.9% | Added |
| Citigroup Inc | 20,169 | $370.5K | 0.00% | +19,546+3,137.4% | Added |
| Brevan Howard Capital Management LP | 19,530 | $358.8K | 0.00% | +19,530 | New |
| Morgan Stanley | 18,577 | $341.3K | 0.00% | −8,944−32.5% | Reduced |
| Omers Administration Corp | 17,800 | $327.0K | 0.00% | +6,200+53.4% | Added |
| Northern Trust Corp | 17,229 | $316.5K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 15,694 | $288.3K | 0.00% | +12,109+337.8% | Added |
| Algert Global LLC | 13,806 | $253.6K | 0.00% | +13,806 | New |
| Verdad Advisers, LP | 12,748 | $234.2K | 0.26% | +12,748 | New |
| Cannon Global Investment Management, LLC | 10,200 | $187.4K | 0.45% | +10,200 | New |
| Vanguard Global Advisers, LLC | 3,469 | $63.7K | 0.00% | +3,469 | New |
| Parallel Advisors, LLC | 264 | $4.85K | 0.00% | +264 | New |
| Allworth Financial LP | 161 | $2.96K | 0.00% | +161 | New |
| SBI Securities Co., Ltd. | 68 | $1.25K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 51 | $1.00K | 0.00% | +31+155.0% | Added |
| Fortitude Family Office, LLC | 40 | $735 | 0.00% | +40 | New |
| Advisor Group Holdings, Inc. | 26 | $477 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 4 | $73 | 0.00% | +4 | New |
| Driehaus Capital Management LLC | 0 | $0 | 0.00% | −302,457−100.0% | Sold out |
| Heights Capital Management, Inc | 0 | $0 | 0.00% | −264,000−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −143,412−100.0% | Sold out |
| Blackstone Group Inc. | 0 | $0 | 0.00% | −75,614−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −64,244−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −32,500−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −22,965−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −13,083−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −409−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −4−100.0% | Sold out |
| Avion Wealth | 0 | $0 | 0.00% | −40−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |