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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Crescent Biopharma, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
54
+6 vs. Q4 2022
Shares held
37.0M
+9.50M (+34.5%) vs. Q4 2022
Total value
$46.6M
−$36.7M (−44.0%) vs. Q4 2022
New holders
19
14 more added
Sold out
13
10 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 54 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ1 2023: $46.6M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q4 2022.

Institutions holding CBIO in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$12.0M0.44%00.0%Unchanged
Artal Group S.A.8,589,064$10.8M0.64%+8,589,064New
NEA Management Company, LLC4,764,440$6.00M0.41%−4,203,266−46.9%Reduced
Octagon Capital Advisors LP3,000,000$3.78M0.55%+3,000,000New
Vanguard Group Inc2,460,833$3.10M0.00%+185,120+8.1%Added
AXA S.A.1,609,061$2.03M0.01%+1,609,061New
Acadian Asset Management LLC1,401,653$1.76M0.01%−541,405−27.9%Reduced
Goldman Sachs Group Inc901,891$1.14M0.00%+834,220+1,232.8%Added
BlackRock Inc.648,915$817.6K0.00%−109,781−14.5%Reduced
Two Sigma Advisers, LP594,500$749.1K0.00%+402,700+210.0%Added
Millennium Management LLC489,793$617.0K0.00%−433,060−46.9%Reduced
Geode Capital Management, LLC405,335$510.7K0.00%00.0%Unchanged
Two Sigma Investments, LP370,569$466.9K0.00%+152,206+69.7%Added
Marshall Wace, LLP216,299$272.5K0.00%+7,358+3.5%Added
State Street Corp186,765$235.3K0.00%+30,200+19.3%Added
Morgan Stanley166,780$210.1K0.00%+150,438+920.6%Added
Connor, Clark & Lunn Investment Management Ltd.159,001$200.3K0.00%+93,713+143.5%Added
Renaissance Technologies LLC143,100$180.0K0.00%−113,900−44.3%Reduced
Franklin Resources Inc120,671$152.0K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC110,400$139.1K0.00%+30,000+37.3%Added
Sargent Investment Group, LLC108,000$135.0K0.04%+108,000New
Northern Trust Corp102,713$129.4K0.00%+5,061+5.2%Added
Stratos Wealth Partners, LTD.102,565$129.2K0.00%+102,565New
Truist Financial Corp101,000$127.3K0.00%+101,000New
Susquehanna International Group, LLP92,109$116.1K0.00%−41,503−31.1%Reduced
Intellectus Partners, LLC81,730$103.0K0.03%00.0%Unchanged
Dimensional Fund Advisors LP66,785$84.1K0.00%−7,493−10.1%Reduced
Beirne Wealth Consulting Services, LLC50,000$63.0K0.04%+10,000+25.0%Added
Letko, Brosseau & Associates Inc45,250$57.0K0.00%+45,250New
Cubist Systematic Strategies, LLC44,939$56.6K0.00%−3,358−7.0%Reduced
Ieq Capital, LLC38,363$48.3K0.00%00.0%Unchanged
Parallax Volatility Advisers, L.P.37,604$47.4K0.00%+37,604New
DLD Asset Management, LP29,200$36.8K0.00%+29,200New
Jane Street Group, LLC26,732$33.7K0.00%+1,932+7.8%Added
Bank of New York Mellon Corp25,172$31.7K0.00%−996−3.8%Reduced
Tower Research Capital LLC (TRC)24,441$30.0K0.00%+24,441New
Charles Schwab Investment Management Inc22,361$28.2K0.00%00.0%Unchanged
Chicago Partners Investment Group LLC20,000$28.0K0.00%+20,000New
Pine Valley Investments Ltd Liability Co12,520$19.0K0.00%+12,520New
Tobias Financial Advisors, Inc.15,000$18.9K0.01%+15,000New
Wolverine Trading, LLC11,879$15.0K0.00%+11,879New
UBS Group AG11,420$14.4K0.00%+11,420New
Creative Planning10,000$12.6K0.00%+10,000New
Commonwealth Equity Services, LLC10,000$12.0K0.00%00.0%Unchanged
Bank of America Corp8,232$10.4K0.00%+8,114+6,876.3%Added
Caption Management, LLC6,657$8.39K0.00%+6,657New
JPMorgan Chase & Co6,170$8.00K0.00%+6,170New
Hartford Financial Management Inc.3,500$4.41K0.00%00.0%Unchanged
Federated Hermes, Inc.3,395$4.28K0.00%−643−15.9%Reduced
Truvestments Capital LLC2,057$2.59K0.00%+2,057New
BNP Paribas Arbitrage, SA481$6060.00%00.0%Unchanged
Carolinas Wealth Consulting LLC395$4980.00%00.0%Unchanged
Wells Fargo & Company294$3700.00%+5+1.7%Added
Barclays PLC76$960.00%00.0%Unchanged
First Manhattan Co0$00.00%−314,141−100.0%Sold out
Eversept Partners, LP0$00.00%−100,579−100.0%Sold out
Simplex Trading, LLC0$00.00%−67,567−100.0%Sold out
XTX Topco Ltd0$00.00%−63,599−100.0%Sold out
Citadel Advisors LLC0$00.00%−50,322−100.0%Sold out
Pura Vida Investments, LLC0$00.00%−31,615−100.0%Sold out
AE Wealth Management LLC0$00.00%−26,898−100.0%Sold out
Prentiss Smith & Co Inc0$00.00%−15,120−100.0%Sold out
Group One Trading, L.P.0$00.00%−12,834−100.0%Sold out
Freedom Wealth Alliance, LLC0$00.00%−9,452−100.0%Sold out
Royal Bank of Canada0$00.00%−2,000−100.0%Sold out
Archer Investment Corp0$00.00%−1,000−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−600−100.0%Sold out