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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Crescent Biopharma, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
58
+9 vs. Q3 2023
Shares held
35.1M
+375.0K (+1.1%) vs. Q3 2023
Total value
$82.8M
+$30.8M (+59.0%) vs. Q3 2023
New holders
15
13 more added
Sold out
6
14 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 58 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ4 2023: $82.8M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q3 2023.

Institutions holding CBIO in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$22.5M0.56%00.0%Unchanged
Artal Group S.A.8,589,064$20.3M0.69%00.0%Unchanged
NEA Management Company, LLC4,764,440$11.2M0.75%00.0%Unchanged
Octagon Capital Advisors LP3,000,000$7.08M1.13%00.0%Unchanged
Vanguard Group Inc2,421,869$5.72M0.00%00.0%Unchanged
AXA S.A.1,587,298$3.75M0.01%−38,400−2.4%Reduced
Goldman Sachs Group Inc919,355$2.17M0.00%+124,861+15.7%Added
BlackRock Inc.734,983$1.73M0.00%+2790.0%Added
Acadian Asset Management LLC541,176$1.27M0.00%−302,875−35.9%Reduced
Geode Capital Management, LLC478,883$1.13M0.00%+19,038+4.1%Added
Gsa Capital Partners LLP200,993$474.0K0.04%+107,208+114.3%Added
Bridgeway Capital Management, LLC197,200$465.4K0.01%+25,000+14.5%Added
State Street Corp186,765$440.8K0.00%00.0%Unchanged
Two Sigma Advisers, LP165,400$390.3K0.00%−53,600−24.5%Reduced
Connor, Clark & Lunn Investment Management Ltd.143,359$338.3K0.00%−5,747−3.9%Reduced
Renaissance Technologies LLC124,444$294.0K0.00%−76,663−38.1%Reduced
Susquehanna International Group, LLP111,491$263.1K0.00%+111,491New
Northern Trust Corp111,254$262.6K0.00%+5,018+4.7%Added
MJP Associates Inc101,000$238.4K0.06%+101,000New
Advisor OS, LLC101,000$238.4K0.03%+101,000New
Adage Capital Partners GP, L.L.C.100,000$236.0K0.00%+100,000New
ExodusPoint Capital Management, LP95,759$226.0K0.00%+95,759New
Franklin Resources Inc95,751$226.0K0.00%−142−0.1%Reduced
Simplex Trading, LLC72,445$170.0K0.01%+72,445New
Two Sigma Investments, LP59,621$140.7K0.00%−54,451−47.7%Reduced
Sargent Investment Group, LLC58,000$136.9K0.03%00.0%Unchanged
Jane Street Group, LLC57,143$134.9K0.00%+37,176+186.2%Added
Intellectus Partners, LLC50,720$119.7K0.03%−11,255−18.2%Reduced
Letko, Brosseau & Associates Inc45,250$106.8K0.00%00.0%Unchanged
LPL Financial LLC41,000$96.8K0.00%+28,000+215.4%Added
Millennium Management LLC38,888$91.8K0.00%−25,008−39.1%Reduced
Ieq Capital, LLC38,363$90.5K0.00%00.0%Unchanged
Morgan Stanley34,511$81.4K0.00%−5,874−14.5%Reduced
Virtu Financial LLC34,319$81.0K0.01%+34,319New
Group One Trading, L.P.31,253$73.8K0.00%+2,852+10.0%Added
Y-Intercept (Hong Kong) Ltd26,572$62.7K0.01%+26,572New
Bank of New York Mellon Corp24,732$58.4K0.00%−143−0.6%Reduced
Charles Schwab Investment Management Inc22,361$52.8K0.00%00.0%Unchanged
Citigroup Inc21,528$50.8K0.00%+21,528New
Bank of America Corp19,990$47.2K0.00%+11,766+143.1%Added
683 Capital Management, LLC19,384$45.7K0.00%+19,384New
Tobias Financial Advisors, Inc.15,000$35.4K0.01%00.0%Unchanged
Marshall Wace, LLP12,885$30.4K0.00%+12,885New
Pine Valley Investments Ltd Liability Co12,520$29.5K0.00%00.0%Unchanged
Boothbay Fund Management, LLC12,464$29.4K0.00%+12,464New
XTX Topco Ltd11,093$26.2K0.01%−21,629−66.1%Reduced
Citadel Advisors LLC7,886$18.6K0.00%+7,886New
Qube Research & Technologies Ltd4,853$11.5K0.00%+4,454+1,116.3%Added
Hartford Financial Management Inc.3,500$8.26K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,882$6.80K0.00%−1,780−38.2%Reduced
Truvestments Capital LLC2,057$4.86K0.00%00.0%Unchanged
JPMorgan Chase & Co1,613$3.81K0.00%+1,147+246.1%Added
Rhumbline Advisers1,044$2.46K0.00%00.0%Unchanged
UBS Group AG683$1.61K0.00%+683New
ORG Partners LLC500$1.18K0.00%+500New
BNP Paribas Arbitrage, SA481$1.14K0.00%00.0%Unchanged
Wells Fargo & Company377$8900.00%+20+5.6%Added
Barclays PLC76$1790.00%−76−50.0%Reduced
Dimensional Fund Advisors LP0$00.00%−44,532−100.0%Sold out
Acuta Capital Partners, LLC0$00.00%−27,500−100.0%Sold out
Chicago Partners Investment Group LLC0$00.00%−20,000−100.0%Sold out
Commonwealth Equity Services, LLC0$00.00%−10,000−100.0%Sold out
Creative Planning0$00.00%−10,000−100.0%Sold out
Signaturefd, LLC0$00.00%−100−100.0%Sold out