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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Crescent Biopharma, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
35
−6 vs. Q4 2024
Shares held
30.8M
+402.5K (+1.3%) vs. Q4 2024
Total value
$6.46M
−$1.10M (−14.5%) vs. Q4 2024
New holders
6
5 more added
Sold out
12
7 more reduced

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 35 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ1 2025: $6.46M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q4 2024.

Institutions holding CBIO in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$2.00M0.08%00.0%Unchanged
Logos Global Management LP5,400,000$1.13M0.20%00.0%Unchanged
Adage Capital Partners GP, L.L.C.5,091,231$1.07M0.00%00.0%Unchanged
VR Adviser, LLC3,000,000$630.0K0.05%00.0%Unchanged
Vanguard Group Inc2,670,208$560.7K0.00%00.0%Unchanged
Wellington Management Group LLP1,370,297$287.8K0.00%−43,105−3.0%Reduced
BlackRock, Inc.726,300$152.5K0.00%−2,337−0.3%Reduced
Jefferies Financial Group Inc.585,000$122.8K0.00%+161,223+38.0%Added
Geode Capital Management, LLC571,726$120.1K0.00%+50,503+9.7%Added
UBS Group AG465,913$97.8K0.00%+237,045+103.6%Added
Balyasny Asset Management LLC382,573$80.3K0.00%+382,573New
Shay Capital LLC356,768$74.9K0.02%+356,768New
State Street Corp179,265$37.6K0.00%00.0%Unchanged
Northern Trust Corp116,985$24.6K0.00%00.0%Unchanged
Intellectus Partners, LLC45,965$9.65K0.00%00.0%Unchanged
Ieq Capital, LLC38,363$8.06K0.00%00.0%Unchanged
Virtu Financial LLC36,326$8.00K0.00%+36,326New
Susquehanna International Group, LLP30,580$6.42K0.00%−10,185−25.0%Reduced
Group One Trading, L.P.24,425$5.13K0.00%+1,056+4.5%Added
JustInvest LLC16,936$3.56K0.00%−9,368−35.6%Reduced
Two Sigma Securities, LLC15,740$3.31K0.00%+15,740New
Millennium Management LLC13,854$2.91K0.00%−565−3.9%Reduced
Pine Valley Investments Ltd Liability Co12,520$2.63K0.00%00.0%Unchanged
1 North Wealth Services LLC12,000$2.52K0.00%00.0%Unchanged
Firethorn Wealth Partners, LLC11,700$2.46K0.00%+11,700New
HRT Financial LP10,032$2.00K0.00%+10,032New
Tower Research Capital LLC (TRC)9,353$1.96K0.00%−10,206−52.2%Reduced
SBI Securities Co., Ltd.6,942$1.46K0.00%00.0%Unchanged
Morgan Stanley5,176$1.09K0.00%00.0%Unchanged
Truvestments Capital LLC1,309$2750.00%00.0%Unchanged
Bank of America Corp787$1650.00%+26+3.4%Added
BNP Paribas Arbitrage, SA481$1010.00%00.0%Unchanged
JPMorgan Chase & Co126$260.00%−10−7.4%Reduced
Barclays PLC76$160.00%00.0%Unchanged
Royal Bank of Canada2,000$00.00%00.0%Unchanged
ADAR1 Capital Management, LLC0$00.00%−331,827−100.0%Sold out
Caxton Corp0$00.00%−203,578−100.0%Sold out
XTX Topco Ltd0$00.00%−64,243−100.0%Sold out
Jane Street Group, LLC0$00.00%−58,854−100.0%Sold out
Renaissance Technologies LLC0$00.00%−41,153−100.0%Sold out
Ground Swell Capital, LLC0$00.00%−33,230−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−13,760−100.0%Sold out
Baader Bank INC0$00.00%−13,966−100.0%Sold out
HBK Sorce Advisory LLC0$00.00%−11,718−100.0%Sold out
Ikarian Capital, LLC0$00.00%−6,501−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−4,755−100.0%Sold out
Acadian Asset Management LLC0$00.00%−1,096−100.0%Sold out