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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Crescent Biopharma, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
35
−34 vs. Q1 2024
Shares held
25.6M
−11.3M (−30.6%) vs. Q1 2024
Total value
$7.20M
−$103.3M (−93.5%) vs. Q1 2024
New holders
3
6 more added
Sold out
37
16 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 35 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ2 2024: $7.20M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q1 2024.

Institutions holding CBIO in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$2.69M0.08%00.0%Unchanged
Artal Group S.A.8,589,064$2.42M0.06%00.0%Unchanged
Vanguard Group Inc2,696,906$759.4K0.00%−65,075−2.4%Reduced
Renaissance Technologies LLC826,851$232.8K0.00%+685,151+483.5%Added
Goldman Sachs Group Inc804,342$226.5K0.00%−310,366−27.8%Reduced
BlackRock Inc.723,184$203.6K0.00%−9,383−1.3%Reduced
Acadian Asset Management LLC534,753$150.0K0.00%+204,227+61.8%Added
Geode Capital Management, LLC487,242$137.2K0.00%−17,905−3.5%Reduced
Millennium Management LLC186,227$52.4K0.00%−560,727−75.1%Reduced
State Street Corp179,265$50.5K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC135,000$38.0K0.01%+135,000New
Northern Trust Corp127,792$36.0K0.00%−965−0.7%Reduced
Two Sigma Advisers, LP108,800$30.6K0.00%+79,500+271.3%Added
Sargent Investment Group, LLC100,000$28.2K0.01%−8,000−7.4%Reduced
UBS Group AG83,020$23.4K0.00%+81,520+5,434.7%Added
Bridgeway Capital Management, LLC81,800$23.0K0.00%−86,800−51.5%Reduced
Group One Trading, L.P.65,433$18.4K0.00%+36,754+128.2%Added
HRT Financial LP47,683$13.0K0.00%−108,147−69.4%Reduced
Intellectus Partners, LLC45,965$12.9K0.00%−4,755−9.4%Reduced
Letko, Brosseau & Associates Inc45,250$12.7K0.00%00.0%Unchanged
Ieq Capital, LLC38,363$10.8K0.00%00.0%Unchanged
Jane Street Group, LLC29,697$8.36K0.00%−259,578−89.7%Reduced
LPL Financial LLC29,000$8.17K0.00%−29,000−50.0%Reduced
Tobias Financial Advisors, Inc.15,000$4.22K0.00%00.0%Unchanged
LMR Partners LLP14,102$3.97K0.00%00.0%Unchanged
Bank of America Corp5,402$1.52K0.00%−45,541−89.4%Reduced
Morgan Stanley5,176$1.46K0.00%−97,912−95.0%Reduced
EverSource Wealth Advisors, LLC4,755$1.03K0.00%+4,755New
Royal Bank of Canada2,319$1.00K0.00%+319+16.0%Added
Qube Research & Technologies Ltd1,101$3100.00%−219,247−99.5%Reduced
Rhumbline Advisers1,044$2940.00%00.0%Unchanged
National Bank of Canada600$1770.00%+600New
BNP Paribas Arbitrage, SA481$1350.00%00.0%Unchanged
JPMorgan Chase & Co151$430.00%−84,473−99.8%Reduced
Barclays PLC76$210.00%00.0%Unchanged
NEA Management Company, LLC0$00.00%−3,835,039−100.0%Sold out
Octagon Capital Advisors LP0$00.00%−3,000,000−100.0%Sold out
AXA S.A.0$00.00%−1,587,741−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−554,594−100.0%Sold out
Marshall Wace, LLP0$00.00%−217,501−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−180,787−100.0%Sold out
Verition Fund Management LLC0$00.00%−162,428−100.0%Sold out
Man Group plc0$00.00%−149,859−100.0%Sold out
Citigroup Inc0$00.00%−137,667−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−100,000−100.0%Sold out
Simplex Trading, LLC0$00.00%−90,652−100.0%Sold out
American Century Companies Inc0$00.00%−63,642−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.0$00.00%−51,868−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−49,798−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−43,130−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−40,557−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−38,200−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−35,698−100.0%Sold out
Omers Administration Corp0$00.00%−30,600−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−23,622−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−23,339−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−23,156−100.0%Sold out
Charles Schwab Investment Management Inc0$00.00%−22,361−100.0%Sold out
Belvedere Trading LLC0$00.00%−20,465−100.0%Sold out
Squarepoint Ops LLC0$00.00%−20,315−100.0%Sold out
Jump Financial, LLC0$00.00%−20,103−100.0%Sold out
SG Americas Securities, LLC0$00.00%−18,805−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−18,321−100.0%Sold out
CTC Alternative Strategies, Ltd.0$00.00%−17,700−100.0%Sold out
Pine Valley Investments Ltd Liability Co0$00.00%−12,520−100.0%Sold out
Citadel Advisors LLC0$00.00%−9,914−100.0%Sold out
Hartford Financial Management Inc.0$00.00%−3,500−100.0%Sold out
Truvestments Capital LLC0$00.00%−2,057−100.0%Sold out
Old Point Trust & Financial Services N A0$00.00%−500−100.0%Sold out
Wells Fargo & Company0$00.00%−383−100.0%Sold out
FMR LLC0$00.00%−67−100.0%Sold out
Macquarie Group Ltd0$00.00%−1,939−100.0%Sold out