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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Crescent Biopharma, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
48
+13 vs. Q3 2022
Shares held
27.5M
+1.56M (+6.0%) vs. Q3 2022
Total value
$83.3M
+$69.0M (+482.2%) vs. Q3 2022
New holders
18
8 more added
Sold out
5
13 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 48 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ4 2022: $83.3M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q3 2022.

Institutions holding CBIO in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$28.9M1.22%00.0%Unchanged
NEA Management Company, LLC8,967,706$27.2M1.53%−121,335−1.3%Reduced
Vanguard Group Inc2,275,713$6.90M0.00%+396,301+21.1%Added
Acadian Asset Management LLC1,943,058$5.89M0.03%−47,029−2.4%Reduced
Millennium Management LLC922,853$2.80M0.00%+556,601+152.0%Added
BlackRock Inc.758,696$2.30M0.00%−7,189−0.9%Reduced
Geode Capital Management, LLC405,335$1.23M0.00%+46,940+13.1%Added
First Manhattan Co314,141$951.8K0.00%+314,141New
Renaissance Technologies LLC257,000$779.0K0.00%−269,300−51.2%Reduced
Two Sigma Investments, LP218,363$661.6K0.00%−9,940−4.4%Reduced
Marshall Wace, LLP208,941$633.1K0.00%+208,941New
Two Sigma Advisers, LP191,800$581.2K0.00%−15,100−7.3%Reduced
State Street Corp156,565$474.4K0.00%+7,600+5.1%Added
Susquehanna International Group, LLP133,612$404.8K0.00%+133,612New
Franklin Resources Inc120,671$365.6K0.00%00.0%Unchanged
Eversept Partners, LP100,579$304.8K0.03%00.0%Unchanged
Northern Trust Corp97,652$295.9K0.00%−145−0.1%Reduced
Intellectus Partners, LLC81,730$247.6K0.09%−38,770−32.2%Reduced
Bridgeway Capital Management, LLC80,400$243.6K0.01%−75,000−48.3%Reduced
Dimensional Fund Advisors LP74,278$225.0K0.00%+74,278New
Goldman Sachs Group Inc67,671$205.0K0.00%+67,671New
Simplex Trading, LLC67,567$204.0K0.01%+65,386+2,998.0%Added
Connor, Clark & Lunn Investment Management Ltd.65,288$197.8K0.00%+65,288New
XTX Topco Ltd63,599$192.7K0.04%+63,599New
Citadel Advisors LLC50,322$152.5K0.00%+50,322New
Cubist Systematic Strategies, LLC48,297$146.3K0.00%+48,297New
Beirne Wealth Consulting Services, LLC40,000$121.2K0.06%+40,000New
Ieq Capital, LLC38,363$116.2K0.00%00.0%Unchanged
Pura Vida Investments, LLC31,615$95.8K0.02%+31,615New
AE Wealth Management LLC26,898$81.5K0.00%+26,898New
Bank of New York Mellon Corp26,168$79.3K0.00%−70−0.3%Reduced
Jane Street Group, LLC24,800$75.1K0.00%+24,800New
Charles Schwab Investment Management Inc22,361$67.8K0.00%+22,361New
Morgan Stanley16,342$49.5K0.00%−27,288−62.5%Reduced
Prentiss Smith & Co Inc15,120$45.8K0.04%+1,120+8.0%Added
Group One Trading, L.P.12,834$38.9K0.00%+12,834New
Commonwealth Equity Services, LLC10,000$30.0K0.00%00.0%Unchanged
Freedom Wealth Alliance, LLC9,452$28.6K0.04%+9,452New
Federated Hermes, Inc.4,038$12.2K0.00%−1,025−20.2%Reduced
Hartford Financial Management Inc.3,500$10.6K0.00%00.0%Unchanged
Royal Bank of Canada2,000$6.00K0.00%+1,800+900.0%Added
Archer Investment Corp1,000$3.03K0.00%+1,000New
Advisor Group Holdings, Inc.600$2.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA481$1.46K0.00%00.0%Unchanged
Carolinas Wealth Consulting LLC395$1.20K0.00%00.0%Unchanged
Wells Fargo & Company289$8760.00%+7+2.5%Added
Bank of America Corp118$3580.00%−9,186−98.7%Reduced
Barclays PLC76$2300.00%+76New
D. E. Shaw & Co., Inc.0$00.00%−36,630−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−21,577−100.0%Sold out
UBS Group AG0$00.00%−17,262−100.0%Sold out
Man Group plc0$00.00%−17,600−100.0%Sold out
JPMorgan Chase & Co0$00.00%−1−100.0%Sold out