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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Crescent Biopharma, Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
48
−9 vs. Q2 2021
Shares held
29.7M
−1.44M (−4.6%) vs. Q2 2021
Total value
$64.9M
−$7.21M (−10.0%) vs. Q2 2021
New holders
5
9 more added
Sold out
14
22 more reduced

1 institution that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 48 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ3 2021: $64.9M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q2 2021.

Institutions holding CBIO in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$20.9M0.82%00.0%Unchanged
NEA Management Company, LLC9,089,041$19.9M0.25%00.0%Unchanged
Vanguard Group Inc2,260,014$4.95M0.00%−10,443−0.5%Reduced
Acadian Asset Management LLC1,886,087$4.13M0.02%−65,605−3.4%Reduced
Dimensional Fund Advisors LP904,628$1.98M0.00%−274,310−23.3%Reduced
BlackRock Inc.875,151$1.92M0.00%−10,997−1.2%Reduced
Two Sigma Advisers, LP621,000$1.36M0.00%−88,000−12.4%Reduced
Renaissance Technologies LLC596,100$1.30M0.00%−161,593−21.3%Reduced
Two Sigma Investments, LP498,530$1.09M0.00%+272,931+121.0%Added
Millennium Management LLC448,010$981.0K0.00%−238,567−34.7%Reduced
Geode Capital Management, LLC366,301$802.0K0.00%+13,561+3.8%Added
Jacobs Levy Equity Management, Inc365,013$799.0K0.01%+36,049+11.0%Added
Federated Hermes, Inc.344,623$755.0K0.00%+1,051+0.3%Added
D. E. Shaw & Co., Inc.316,786$694.0K0.00%+51,315+19.3%Added
Bridgeway Capital Management, LLC168,700$369.0K0.01%−47,000−21.8%Reduced
Franklin Resources Inc160,700$352.0K0.00%+160,700New
State Street Corp144,265$316.0K0.00%00.0%Unchanged
Susquehanna Fundamental Investments, LLC135,717$297.0K0.01%−9,000−6.2%Reduced
Intellectus Partners, LLC123,000$269.0K0.07%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.112,298$246.0K0.00%+5,856+5.5%Added
Northern Trust Corp97,866$214.0K0.00%−10,847−10.0%Reduced
Susquehanna International Group, LLP80,351$176.0K0.00%+21,252+36.0%Added
Morgan Stanley67,924$148.0K0.00%+23,510+52.9%Added
Virtu Financial LLC54,147$119.0K0.01%+54,147New
Citadel Advisors LLC53,164$117.0K0.00%−53,651−50.2%Reduced
HRT Financial LP51,284$112.0K0.00%−56,865−52.6%Reduced
Ieq Capital, LLC38,363$84.0K0.00%00.0%Unchanged
Charles Schwab Investment Management Inc34,903$77.0K0.00%+23,481+205.6%Added
Advisory Services Network, LLC31,800$70.0K0.00%−4,000−11.2%Reduced
JPMorgan Chase & Co30,649$67.0K0.00%−233,265−88.4%Reduced
Goldman Sachs Group Inc26,375$58.0K0.00%−97,032−78.6%Reduced
Bank of New York Mellon Corp26,299$58.0K0.00%−365−1.4%Reduced
ExodusPoint Capital Management, LP22,432$49.0K0.00%−38,748−63.3%Reduced
Bank of America Corp14,803$32.0K0.00%−24,604−62.4%Reduced
Prentiss Smith & Co Inc14,000$31.0K0.02%00.0%Unchanged
Algert Global LLC11,544$25.0K0.00%+11,544New
Commonwealth Equity Services, LLC10,000$21.0K0.00%00.0%Unchanged
Barclays PLC4,819$11.0K0.00%−14,029−74.4%Reduced
Tower Research Capital LLC (TRC)5,056$11.0K0.00%−10,728−68.0%Reduced
Bank Julius Baer & Co. Ltd, Zurich5,000$11.0K0.00%+5,000New
Lindbrook Capital, LLC5,000$11.0K0.00%+5,000New
Hartford Financial Management Inc.3,500$8.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,100$2.00K0.00%00.0%Unchanged
FMR LLC700$2.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA542$1.19K0.00%00.0%Unchanged
Wells Fargo & Company253$1.00K0.00%−49−16.2%Reduced
Carolinas Wealth Consulting LLC395$1.00K0.00%00.0%Unchanged
UBS Group AG32$00.00%−10,270−99.7%Reduced
Ergoteles LLC0$00.00%−160,900−100.0%Sold out
Tibra Equities Europe Ltd0$00.00%−136,100−100.0%Sold out
AQR Capital Management LLC0$00.00%−97,590−100.0%Sold out
PDT Partners, LLC0$00.00%−82,300−100.0%Sold out
XTX Topco Ltd0$00.00%−58,992−100.0%Sold out
Jane Street Group, LLC0$00.00%−38,642−100.0%Sold out
LMR Partners LLP0$00.00%−22,889−100.0%Sold out
LPL Financial LLC0$00.00%−19,625−100.0%Sold out
Jump Financial, LLC0$00.00%−18,000−100.0%Sold out
Squarepoint Ops LLC0$00.00%−16,216−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−14,488−100.0%Sold out
Royal Bank of Canada0$00.00%−2,997−100.0%Sold out
Perennial Advisors, LLC0$00.00%−980−100.0%Sold out
New York State Common Retirement Fund0$00.00%−320−100.0%Sold out
QS Investors, LLC––––Not filed