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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Crescent Biopharma, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
41
+5 vs. Q3 2024
Shares held
30.4M
+12.6M (+70.6%) vs. Q3 2024
Total value
$7.56M
+$4.55M (+151.6%) vs. Q3 2024
New holders
16
6 more added
Sold out
11
5 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 41 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ4 2024: $7.56M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q3 2024.

Institutions holding CBIO in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$2.38M0.08%00.0%Unchanged
Logos Global Management LP5,400,000$1.34M0.16%+5,400,000New
Adage Capital Partners GP, L.L.C.5,091,231$1.27M0.00%+5,091,231New
VR Adviser, LLC3,000,000$747.0K0.05%+3,000,000New
Vanguard Group Inc2,670,208$664.9K0.00%00.0%Unchanged
Wellington Management Group LLP1,413,402$351.9K0.00%+1,413,402New
BlackRock, Inc.728,637$181.4K0.00%+779+0.1%Added
Geode Capital Management, LLC521,223$129.8K0.00%00.0%Unchanged
Jefferies Financial Group Inc.423,777$105.5K0.00%+423,777New
ADAR1 Capital Management, LLC331,827$82.6K0.02%+286,127+626.1%Added
UBS Group AG228,868$57.0K0.00%+160,428+234.4%Added
Caxton Corp203,578$50.9K0.31%+203,578New
State Street Corp179,265$44.6K0.00%00.0%Unchanged
Northern Trust Corp116,985$29.1K0.00%00.0%Unchanged
XTX Topco Ltd64,243$16.0K0.00%+39,314+157.7%Added
Jane Street Group, LLC58,854$14.7K0.00%+58,854New
Intellectus Partners, LLC45,965$11.4K0.00%00.0%Unchanged
Renaissance Technologies LLC41,153$10.2K0.00%−739,947−94.7%Reduced
Susquehanna International Group, LLP40,765$10.2K0.00%+40,765New
Ieq Capital, LLC38,363$9.55K0.00%00.0%Unchanged
Ground Swell Capital, LLC33,230$8.27K0.02%+33,230New
JustInvest LLC26,304$6.55K0.00%+26,304New
Group One Trading, L.P.23,369$5.82K0.00%−14,648−38.5%Reduced
Tower Research Capital LLC (TRC)19,559$4.87K0.00%+19,559New
Millennium Management LLC14,419$3.59K0.00%−4,446−23.6%Reduced
Cubist Systematic Strategies, LLC13,760$3.43K0.00%+13,760New
Pine Valley Investments Ltd Liability Co12,520$3.12K0.00%00.0%Unchanged
Baader Bank INC13,966$3.11K0.00%+3,294+30.9%Added
1 North Wealth Services LLC12,000$2.99K0.00%+12,000New
HBK Sorce Advisory LLC11,718$2.92K0.00%+11,718New
SBI Securities Co., Ltd.6,942$1.73K0.00%+6,942New
Ikarian Capital, LLC6,501$1.62K0.00%+6,501New
Morgan Stanley5,176$1.29K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC4,755$1.18K0.00%00.0%Unchanged
Truvestments Capital LLC1,309$3260.00%00.0%Unchanged
Bank of America Corp761$1900.00%+297+64.0%Added
BNP Paribas Arbitrage, SA481$1200.00%00.0%Unchanged
JPMorgan Chase & Co136$340.00%−5−3.5%Reduced
Barclays PLC76$190.00%00.0%Unchanged
Acadian Asset Management LLC1,096$00.00%−356,343−99.7%Reduced
Royal Bank of Canada2,000$00.00%00.0%Unchanged
Siren, L.L.C.0$00.00%−1,965,114−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−248,958−100.0%Sold out
HCR Wealth Advisors0$00.00%−100,000−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−83,725−100.0%Sold out
Two Sigma Investments, LP0$00.00%−44,646−100.0%Sold out
LPL Financial LLC0$00.00%−30,700−100.0%Sold out
HRT Financial LP0$00.00%−32,324−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−22,158−100.0%Sold out
Virtu Financial LLC0$00.00%−19,542−100.0%Sold out
Tobias Financial Advisors, Inc.0$00.00%−15,000−100.0%Sold out
Jump Financial, LLC0$00.00%−11,506−100.0%Sold out