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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Crescent Biopharma, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
30
−5 vs. Q1 2025
Shares held
10.8M
−20.0M (−65.0%) vs. Q1 2025
Total value
$173.5M
+$167.1M (+2,586.9%) vs. Q1 2025
New holders
15
3 more added
Sold out
20
12 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 30 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ2 2025: $173.5M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q1 2025.

Institutions holding CBIO in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC1,414,190$22.8M0.00%+1,414,190New
Fairmount Funds Management LLC1,387,866$22.4M2.90%+1,387,866New
VR Adviser, LLC1,387,864$22.4M1.68%−1,612,136−53.7%Reduced
BVF Inc1,387,863$22.4M0.80%−8,156,399−85.5%Reduced
Paradigm Biocapital Advisors LP642,721$10.4M0.44%+642,721New
Logos Global Management LP553,686$8.94M1.19%−4,846,314−89.7%Reduced
Perceptive Advisors LLC453,686$7.32M0.27%+453,686New
Commodore Capital LP453,686$7.32M0.52%+453,686New
Deep Track Capital, LP453,686$7.32M0.24%+453,686New
Boxer Capital Management, LLC453,686$7.32M3.69%+453,686New
Frazier Life Sciences Management, L.P.453,685$7.32M0.29%+453,685New
Soleus Capital Management, L.P.400,000$6.46M0.45%+400,000New
Driehaus Capital Management LLC302,457$4.88M0.04%+302,457New
Affinity Asset Advisors, LLC280,031$4.52M0.67%+280,031New
Braidwell LP261,504$4.22M0.14%+261,504New
Wellington Management Group LLP179,886$2.90M0.00%−1,190,411−86.9%Reduced
Adage Capital Partners GP, L.L.C.100,912$1.63M0.00%−4,990,319−98.0%Reduced
Blackstone Group Inc.75,614$1.22M0.01%+75,614New
Tang Capital Management LLC50,152$809.5K0.04%+50,152New
Jefferies Financial Group Inc.27,096$437.3K0.01%−557,904−95.4%Reduced
Morgan Stanley15,394$248.5K0.00%+10,218+197.4%Added
Bank of America Corp9,231$149.0K0.00%+8,444+1,072.9%Added
BlackRock, Inc.6,051$97.7K0.00%−720,249−99.2%Reduced
Barclays PLC286$4.62K0.00%+210+276.3%Added
UBS Group AG223$3.60K0.00%−465,690−100.0%Reduced
Group One Trading, L.P.162$2.62K0.00%−24,263−99.3%Reduced
SBI Securities Co., Ltd.68$1.10K0.00%−6,874−99.0%Reduced
Raymond James Financial Inc50$8070.00%+50New
BNP Paribas Arbitrage, SA4$650.00%−477−99.2%Reduced
Royal Bank of Canada20$00.00%−1,980−99.0%Reduced
Vanguard Group Inc0$00.00%−2,670,208−100.0%Sold out
Geode Capital Management, LLC0$00.00%−571,726−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−382,573−100.0%Sold out
Shay Capital LLC0$00.00%−356,768−100.0%Sold out
State Street Corp0$00.00%−179,265−100.0%Sold out
Northern Trust Corp0$00.00%−116,985−100.0%Sold out
Intellectus Partners, LLC0$00.00%−45,965−100.0%Sold out
Ieq Capital, LLC0$00.00%−38,363−100.0%Sold out
Virtu Financial LLC0$00.00%−36,326−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−30,580−100.0%Sold out
JustInvest LLC0$00.00%−16,936−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−15,740−100.0%Sold out
Millennium Management LLC0$00.00%−13,854−100.0%Sold out
Pine Valley Investments Ltd Liability Co0$00.00%−12,520−100.0%Sold out
1 North Wealth Services LLC0$00.00%−12,000−100.0%Sold out
Firethorn Wealth Partners, LLC0$00.00%−11,700−100.0%Sold out
HRT Financial LP0$00.00%−10,032−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−9,353−100.0%Sold out
Truvestments Capital LLC0$00.00%−1,309−100.0%Sold out
JPMorgan Chase & Co0$00.00%−126−100.0%Sold out