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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Crescent Biopharma, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
47
−1 vs. Q3 2021
Shares held
29.7M
+34.1K (+0.1%) vs. Q3 2021
Total value
$42.7M
−$22.2M (−34.2%) vs. Q3 2021
New holders
5
17 more added
Sold out
6
14 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 47 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ4 2021: $42.7M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q3 2021.

Institutions holding CBIO in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$13.7M0.50%00.0%Unchanged
NEA Management Company, LLC9,089,041$13.1M0.26%00.0%Unchanged
Vanguard Group Inc2,238,553$3.22M0.00%−21,461−0.9%Reduced
Acadian Asset Management LLC1,951,086$2.81M0.01%+64,999+3.4%Added
BlackRock Inc.872,858$1.26M0.00%−2,293−0.3%Reduced
Millennium Management LLC691,713$996.0K0.00%+243,703+54.4%Added
Two Sigma Advisers, LP654,800$943.0K0.00%+33,800+5.4%Added
Two Sigma Investments, LP610,262$879.0K0.00%+111,732+22.4%Added
Renaissance Technologies LLC601,300$866.0K0.00%+5,200+0.9%Added
Dimensional Fund Advisors LP564,388$813.0K0.00%−340,240−37.6%Reduced
Geode Capital Management, LLC365,106$525.0K0.00%−1,195−0.3%Reduced
Federated Hermes, Inc.345,452$497.0K0.00%+829+0.2%Added
D. E. Shaw & Co., Inc.267,871$385.0K0.00%−48,915−15.4%Reduced
Susquehanna International Group, LLP265,208$382.0K0.00%+184,857+230.1%Added
Franklin Resources Inc160,307$231.0K0.00%−393−0.2%Reduced
Bridgeway Capital Management, LLC155,400$224.0K0.00%−13,300−7.9%Reduced
Gsa Capital Partners LLP146,078$210.0K0.03%+146,078New
State Street Corp144,265$208.0K0.00%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.119,395$172.0K0.00%+7,097+6.3%Added
Eversept Partners, LP100,000$144.0K0.01%+100,000New
Northern Trust Corp98,487$142.0K0.00%+621+0.6%Added
Simplex Trading, LLC99,302$142.0K0.00%+99,302New
Citadel Advisors LLC96,275$138.0K0.00%+43,111+81.1%Added
Susquehanna Fundamental Investments, LLC90,876$131.0K0.00%−44,841−33.0%Reduced
Intellectus Partners, LLC80,500$116.0K0.03%−42,500−34.6%Reduced
Morgan Stanley53,155$76.0K0.00%−14,769−21.7%Reduced
Ieq Capital, LLC38,363$55.0K0.00%00.0%Unchanged
Goldman Sachs Group Inc38,533$55.0K0.00%+12,158+46.1%Added
Charles Schwab Investment Management Inc34,903$51.0K0.00%00.0%Unchanged
ExodusPoint Capital Management, LP29,290$42.0K0.00%+6,858+30.6%Added
Bank of New York Mellon Corp26,299$38.0K0.00%00.0%Unchanged
Algert Global LLC26,174$38.0K0.00%+14,630+126.7%Added
UBS Group AG21,054$30.0K0.00%+21,022+65,693.8%Added
Prentiss Smith & Co Inc14,000$20.0K0.01%00.0%Unchanged
Bank of America Corp11,714$17.0K0.00%−3,089−20.9%Reduced
XR Securities LLC10,395$15.0K0.00%+10,395New
Commonwealth Equity Services, LLC10,000$14.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)7,272$10.0K0.00%+2,216+43.8%Added
Bank Julius Baer & Co. Ltd, Zurich5,000$7.00K0.00%00.0%Unchanged
Hartford Financial Management Inc.3,500$5.00K0.00%00.0%Unchanged
JPMorgan Chase & Co1,238$2.00K0.00%−29,411−96.0%Reduced
FMR LLC1,000$1.00K0.00%+300+42.9%Added
Advisor Group Holdings, Inc.600$1.00K0.00%−500−45.5%Reduced
Carolinas Wealth Consulting LLC395$1.00K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA481$6930.00%−61−11.3%Reduced
Wells Fargo & Company254$00.00%+1+0.4%Added
FinTrust Capital Advisors, LLC245$00.00%+245New
Jacobs Levy Equity Management, Inc0$00.00%−365,013−100.0%Sold out
Virtu Financial LLC0$00.00%−54,147−100.0%Sold out
HRT Financial LP0$00.00%−51,284−100.0%Sold out
Advisory Services Network, LLC0$00.00%−31,800−100.0%Sold out
Barclays PLC0$00.00%−4,819−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−5,000−100.0%Sold out