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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Crescent Biopharma, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
+11 vs. Q4 2023
Shares held
36.8M
+1.75M (+5.0%) vs. Q4 2023
Total value
$110.5M
+$27.7M (+33.4%) vs. Q4 2023
New holders
21
24 more added
Sold out
10
9 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 69 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ1 2024: $110.5M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q4 2023.

Institutions holding CBIO in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BVF Inc9,544,262$28.6M0.79%00.0%Unchanged
Artal Group S.A.8,589,064$25.8M0.66%00.0%Unchanged
NEA Management Company, LLC3,835,039$11.5M0.71%−929,401−19.5%Reduced
Octagon Capital Advisors LP3,000,000$9.00M1.09%00.0%Unchanged
Vanguard Group Inc2,761,981$8.29M0.00%+340,112+14.0%Added
AXA S.A.1,587,741$4.76M0.01%+4430.0%Added
Goldman Sachs Group Inc1,114,708$3.34M0.00%+195,353+21.2%Added
Millennium Management LLC746,954$2.24M0.00%+708,066+1,820.8%Added
BlackRock Inc.732,567$2.20M0.00%−2,416−0.3%Reduced
Susquehanna International Group, LLP554,594$1.66M0.00%+443,103+397.4%Added
Geode Capital Management, LLC505,147$1.52M0.00%+26,264+5.5%Added
Acadian Asset Management LLC330,526$991.0K0.00%−210,650−38.9%Reduced
Jane Street Group, LLC289,275$867.8K0.00%+232,132+406.2%Added
Qube Research & Technologies Ltd220,348$661.0K0.00%+215,495+4,440.4%Added
Marshall Wace, LLP217,501$652.5K0.00%+204,616+1,588.0%Added
Connor, Clark & Lunn Investment Management Ltd.180,787$542.4K0.00%+37,428+26.1%Added
State Street Corp179,265$537.8K0.00%−7,500−4.0%Reduced
Bridgeway Capital Management, LLC168,600$505.8K0.01%−28,600−14.5%Reduced
Verition Fund Management LLC162,428$487.3K0.00%+162,428New
HRT Financial LP155,830$467.0K0.00%+155,830New
Man Group plc149,859$449.6K0.00%+149,859New
Renaissance Technologies LLC141,700$425.0K0.00%+17,256+13.9%Added
Citigroup Inc137,667$413.0K0.00%+116,139+539.5%Added
Northern Trust Corp128,757$386.3K0.00%+17,503+15.7%Added
Sargent Investment Group, LLC108,000$324.0K0.07%+50,000+86.2%Added
Morgan Stanley103,088$309.3K0.00%+68,577+198.7%Added
Adage Capital Partners GP, L.L.C.100,000$300.0K0.00%00.0%Unchanged
Simplex Trading, LLC90,652$271.0K0.01%+18,207+25.1%Added
JPMorgan Chase & Co84,624$253.9K0.00%+83,011+5,146.4%Added
American Century Companies Inc63,642$190.9K0.00%+63,642New
LPL Financial LLC58,000$174.0K0.00%+17,000+41.5%Added
Point72 Asia (Singapore) Pte. Ltd.51,868$155.6K0.04%+51,868New
Bank of America Corp50,943$152.8K0.00%+30,953+154.8%Added
Intellectus Partners, LLC50,720$152.2K0.04%00.0%Unchanged
Cubist Systematic Strategies, LLC49,798$149.4K0.00%+49,798New
Letko, Brosseau & Associates Inc45,250$135.8K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd43,130$129.4K0.01%+16,558+62.3%Added
Balyasny Asset Management LLC40,557$121.7K0.00%+40,557New
Ieq Capital, LLC38,363$115.1K0.00%00.0%Unchanged
Jefferies Financial Group Inc.38,200$114.6K0.00%+38,200New
ExodusPoint Capital Management, LP35,698$107.0K0.00%−60,061−62.7%Reduced
Omers Administration Corp30,600$91.8K0.00%+30,600New
Two Sigma Advisers, LP29,300$87.9K0.00%−136,100−82.3%Reduced
Group One Trading, L.P.28,679$86.0K0.00%−2,574−8.2%Reduced
Tower Research Capital LLC (TRC)23,622$70.9K0.00%+20,740+719.6%Added
Brevan Howard Capital Management LP23,339$70.0K0.01%+23,339New
Dimensional Fund Advisors LP23,156$69.5K0.00%+23,156New
Charles Schwab Investment Management Inc22,361$67.1K0.00%00.0%Unchanged
Belvedere Trading LLC20,465$61.4K0.00%+20,465New
Squarepoint Ops LLC20,315$60.9K0.00%+20,315New
Jump Financial, LLC20,103$60.3K0.00%+20,103New
SG Americas Securities, LLC18,805$56.0K0.00%+18,805New
Gsa Capital Partners LLP18,321$55.0K0.00%−182,672−90.9%Reduced
CTC Alternative Strategies, Ltd.17,700$53.1K0.03%+17,700New
Tobias Financial Advisors, Inc.15,000$45.0K0.01%00.0%Unchanged
LMR Partners LLP14,102$42.3K0.00%+14,102New
Pine Valley Investments Ltd Liability Co12,520$37.6K0.00%00.0%Unchanged
Citadel Advisors LLC9,914$29.7K0.00%+2,028+25.7%Added
Hartford Financial Management Inc.3,500$10.5K0.00%00.0%Unchanged
Truvestments Capital LLC2,057$6.17K0.00%00.0%Unchanged
Royal Bank of Canada2,000$6.00K0.00%+2,000New
UBS Group AG1,500$4.50K0.00%+817+119.6%Added
Rhumbline Advisers1,044$3.13K0.00%00.0%Unchanged
Old Point Trust & Financial Services N A500$1.50K0.00%+500New
BNP Paribas Arbitrage, SA481$1.44K0.00%00.0%Unchanged
Wells Fargo & Company383$1.15K0.00%+6+1.6%Added
Barclays PLC76$2280.00%00.0%Unchanged
FMR LLC67$2010.00%+67New
Macquarie Group Ltd1,939$60.00%+1,939New
MJP Associates Inc0$00.00%−101,000−100.0%Sold out
Advisor OS, LLC0$00.00%−101,000−100.0%Sold out
Franklin Resources Inc0$00.00%−95,751−100.0%Sold out
Two Sigma Investments, LP0$00.00%−59,621−100.0%Sold out
Virtu Financial LLC0$00.00%−34,319−100.0%Sold out
Bank of New York Mellon Corp0$00.00%−24,732−100.0%Sold out
683 Capital Management, LLC0$00.00%−19,384−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−12,464−100.0%Sold out
XTX Topco Ltd0$00.00%−11,093−100.0%Sold out
ORG Partners LLC0$00.00%−500−100.0%Sold out