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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Crescent Biopharma, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
41
+11 vs. Q2 2025
Shares held
11.3M
+567.1K (+5.3%) vs. Q2 2025
Total value
$134.6M
−$39.0M (−22.4%) vs. Q2 2025
New holders
15
7 more added
Sold out
4
8 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 41 institutions
Q1 2021: 78 institutionsQ2 2021: 58 institutionsQ3 2021: 48 institutionsQ4 2021: 47 institutionsQ1 2022: 44 institutionsQ2 2022: 37 institutionsQ3 2022: 35 institutionsQ4 2022: 48 institutionsQ1 2023: 54 institutionsQ2 2023: 55 institutionsQ3 2023: 49 institutionsQ4 2023: 58 institutionsQ1 2024: 69 institutionsQ2 2024: 35 institutionsQ3 2024: 36 institutionsQ4 2024: 41 institutionsQ1 2025: 35 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ3 2025: $134.6M
Q1 2021: $110.4MQ2 2021: $72.5MQ3 2021: $64.9MQ4 2021: $42.7MQ1 2022: $31.2MQ2 2022: $15.8MQ3 2022: $14.3MQ4 2022: $83.3MQ1 2023: $46.6MQ2 2023: $61.9MQ3 2023: $52.1MQ4 2023: $82.8MQ1 2024: $110.5MQ2 2024: $7.20MQ3 2024: $3.00MQ4 2024: $7.56MQ1 2025: $6.46MQ2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 202535$6.46M
Q4 202441$7.56M
Q3 202436$3.00M
Q2 202435$7.20M
Q1 202469$110.5M
Q4 202358$82.8M
Q3 202349$52.1M
Q2 202355$61.9M
Q1 202354$46.6M
Q4 202248$83.3M
Q3 202235$14.3M
Q2 202237$15.8M
Q1 202244$31.2M
Q4 202147$42.7M
Q3 202148$64.9M
Q2 202158$72.5M
Q1 202178$110.4M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q2 2025.

Institutions holding CBIO in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC1,414,680$16.8M0.00%+4900.0%Added
Fairmount Funds Management LLC1,387,866$16.5M1.48%00.0%Unchanged
VR Adviser, LLC1,387,864$16.5M0.93%00.0%Unchanged
BVF Inc1,387,863$16.5M0.67%00.0%Unchanged
Tang Capital Management LLC679,824$8.08M0.31%+629,672+1,255.5%Added
Vanguard Group Inc657,900$7.82M0.00%+657,900New
Logos Global Management LP600,000$7.13M0.70%+46,314+8.4%Added
Perceptive Advisors LLC453,686$5.39M0.16%00.0%Unchanged
Deep Track Capital, LP453,686$5.39M0.15%00.0%Unchanged
Boxer Capital Management, LLC453,686$5.39M1.72%00.0%Unchanged
Commodore Capital LP450,829$5.36M0.26%−2,857−0.6%Reduced
Price T Rowe Associates Inc383,595$4.56M0.00%+383,595New
Driehaus Capital Management LLC302,457$3.60M0.03%00.0%Unchanged
Frazier Life Sciences Management, L.P.272,951$3.25M0.10%−180,734−39.8%Reduced
Adage Capital Partners GP, L.L.C.200,005$2.38M0.00%+99,093+98.2%Added
Soleus Capital Management, L.P.200,000$2.38M0.13%−200,000−50.0%Reduced
BlackRock, Inc.109,115$1.30M0.00%+103,064+1,703.3%Added
Jefferies Financial Group Inc.102,714$1.22M0.01%+75,618+279.1%Added
Blackstone Group Inc.75,614$899.0K0.00%00.0%Unchanged
Geode Capital Management, LLC69,134$822.0K0.00%+69,134New
Marshall Wace, LLP43,694$519.5K0.00%+43,694New
Goldman Sachs Group Inc36,975$439.6K0.00%+36,975New
Two Sigma Investments, LP28,318$336.7K0.00%+28,318New
Renaissance Technologies LLC26,900$319.8K0.00%+26,900New
Citadel Advisors LLC25,593$304.3K0.00%+25,593New
Manufacturers Life Insurance Company, The24,923$296.3K0.00%+24,923New
State Street Corp18,617$221.4K0.00%+18,617New
Affinity Asset Advisors, LLC17,998$214.0K0.02%−262,033−93.6%Reduced
Wellington Management Group LLP17,698$210.4K0.00%−162,188−90.2%Reduced
Northern Trust Corp16,816$199.9K0.00%+16,816New
UBS Group AG12,661$150.5K0.00%+12,438+5,577.6%Added
Bank of America Corp3,863$45.9K0.00%−5,368−58.2%Reduced
Citigroup Inc798$9.49K0.00%+798New
Tower Research Capital LLC (TRC)200$2.38K0.00%+200New
Morgan Stanley145$1.72K0.00%−15,249−99.1%Reduced
Group One Trading, L.P.82$9750.00%−80−49.4%Reduced
SBI Securities Co., Ltd.68$8090.00%00.0%Unchanged
Advisor Group Holdings, Inc.26$3740.00%+26New
JPMorgan Chase & Co17$2020.00%+17New
BNP Paribas Arbitrage, SA4$480.00%00.0%Unchanged
Royal Bank of Canada20$00.00%00.0%Unchanged
Paradigm Biocapital Advisors LP0$00.00%−642,721−100.0%Sold out
Braidwell LP0$00.00%−261,504−100.0%Sold out
Barclays PLC0$00.00%−286−100.0%Sold out
Raymond James Financial Inc0$00.00%−50−100.0%Sold out