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Crescent Biopharma, Inc.

CBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001253689

In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Crescent Biopharma, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
82
+19 vs. Q1 2026
Shares held
29.6M
+3.64M (+14.0%) vs. Q1 2026
Total value
$532.6M
+$55.9M (+11.7%) vs. Q1 2026
New holders
31
17 more added
Sold out
12
15 more reduced

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 82 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 30 institutionsQ3 2025: 41 institutionsQ4 2025: 58 institutionsQ1 2026: 63 institutionsQ2 2026: 82 institutions
Value heldQ2 2026: $532.6M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $173.5MQ3 2025: $134.6MQ4 2025: $285.9MQ1 2026: $476.6MQ2 2026: $532.6M
Institutions holding CBIO and their total value by quarter
QuarterHoldersValue
Q2 202682$532.6M
Q1 202663$476.6M
Q4 202558$285.9M
Q3 202541$134.6M
Q2 202530$173.5M
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q1 2026.

Institutions holding CBIO in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC4,133,514$74.4M0.00%00.0%Unchanged
BVF Inc2,748,763$49.5M1.27%00.0%Unchanged
Fairmount Funds Management LLC2,747,866$49.5M3.27%00.0%Unchanged
VR Adviser, LLC2,133,576$38.4M1.16%00.0%Unchanged
Logos Global Management LP1,900,000$34.2M1.47%+1,417,500+293.8%Added
FCPM III Services B.V.1,677,852$30.2M4.02%00.0%Unchanged
Balyasny Asset Management LLC1,662,917$29.9M0.05%+152,884+10.1%Added
Vestal Point Capital, LP1,630,000$29.3M0.69%+130,000+8.7%Added
Opaleye Management Inc.1,319,351$23.7M2.15%+6,736+0.5%Added
BlackRock, Inc.1,271,762$22.9M0.00%+1,156,037+999.0%Added
Tang Capital Management LLC1,160,000$20.9M0.95%00.0%Unchanged
Vanguard Capital Management LLC767,755$13.8M0.00%−33,640−4.2%Reduced
Boxer Capital Management, LLC453,686$8.17M0.62%00.0%Unchanged
Millennium Management LLC403,859$7.27M0.00%+80,306+24.8%Added
Geode Capital Management, LLC384,576$6.92M0.00%+280,355+269.0%Added
Jennison Associates LLC378,507$6.81M0.00%+225,533+147.4%Added
RTW Investments, LP372,856$6.71M0.06%00.0%Unchanged
NEXTBio Capital Management LP372,856$6.71M3.09%00.0%Unchanged
Remedium Capital Partners, LLC361,250$6.50M1.44%00.0%Unchanged
State Street Corp315,587$5.68M0.00%+276,520+707.8%Added
Ameriprise Financial Inc302,568$5.45M0.00%+302,568New
Point72 Asset Management, L.P.300,000$5.40M0.01%00.0%Unchanged
Price T Rowe Associates Inc275,581$4.96M0.00%−27,970−9.2%Reduced
Marshall Wace, LLP214,300$3.86M0.00%+13,520+6.7%Added
Perceptive Advisors LLC206,942$3.72M0.06%00.0%Unchanged
Vanguard Portfolio Management LLC188,803$3.40M0.00%+188,803New
Two Sigma Investments, LP186,874$3.36M0.00%+71,046+61.3%Added
StemPoint Capital LP182,382$3.28M0.57%+182,382New
UBS Group AG175,182$3.15M0.00%+92,476+111.8%Added
Northern Trust Corp138,778$2.50M0.00%+121,549+705.5%Added
Exome Asset Management LLC127,769$2.30M1.42%−25,422−16.6%Reduced
Sectoral Asset Management Inc121,300$2.18M1.52%+121,300New
Woodline Partners LP94,488$1.70M0.01%+20,488+27.7%Added
Vanguard Fiduciary Trust Co75,225$1.35M0.00%+25,802+52.2%Added
Burkehill Global Management, LP74,000$1.33M0.05%00.0%Unchanged
Blackstone Group Inc.62,647$1.13M0.00%+62,647New
Silverarc Capital Management, LLC59,104$1.06M0.12%−71,396−54.7%Reduced
Y-Intercept (Hong Kong) Ltd50,824$914.8K0.02%+50,824New
Charles Schwab Investment Management Inc50,258$904.6K0.00%+50,258New
Nuveen, LLC47,629$857.3K0.00%+47,629New
Bank of New York Mellon Corp45,778$824.0K0.00%+45,778New
Stonepine Capital Management, LLC40,000$720.0K0.55%−45,000−52.9%Reduced
Bank of America Corp25,821$464.8K0.00%−3,456−11.8%Reduced
Rhumbline Advisers25,487$458.8K0.00%+25,487New
Moore Capital Management, LP25,000$450.0K0.01%00.0%Unchanged
Squarepoint Ops LLC24,166$435.0K0.00%+24,166New
American Century Companies Inc22,805$410.5K0.00%+22,805New
Wells Fargo & Company19,700$354.6K0.00%+19,700New
Quadrature Capital Ltd19,227$346.1K0.00%−1,690−8.1%Reduced
ADAR1 Capital Management, LLC18,275$328.9K0.02%−31,998−63.6%Reduced
Virtus Investment Advisers, Inc.18,258$328.6K0.08%+18,258New
Manufacturers Life Insurance Company, The17,755$319.6K0.00%−7,148−28.7%Reduced
Morgan Stanley17,698$318.6K0.00%−879−4.7%Reduced
Wellington Management Group LLP14,600$262.8K0.00%+14,600New
Bank of Montreal13,768$247.8K0.00%+13,768New
MetLife Investment Management12,780$230.0K0.00%+12,780New
Invesco Ltd.11,731$211.2K0.00%+11,731New
Persistent Asset Partners Ltd10,968$197.4K0.06%+10,968New
XTX Topco Ltd10,564$190.2K0.00%+10,564New
Citigroup Inc10,141$182.5K0.00%−10,028−49.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.9,901$178.2K0.00%+9,901New
JPMorgan Chase & Co9,020$162.4K0.00%−31,984−78.0%Reduced
New York State Common Retirement Fund7,600$136.8K0.00%+7,600New
Police & Firemen's Retirement System of New Jersey6,369$114.6K0.00%+6,369New
Barclays PLC4,462$80.3K0.00%−25,727−85.2%Reduced
BNP Paribas Arbitrage, SA3,303$59.5K0.00%−12,391−79.0%Reduced
Vanguard Global Advisers, LLC2,714$48.9K0.00%−755−21.8%Reduced
Legal & General Group Plc2,097$37.7K0.00%+2,097New
Tower Research Capital LLC (TRC)1,761$31.7K0.00%+1,761New
Russell Investments Group, Ltd.1,726$31.1K0.00%+1,726New
Royal Bank of Canada681$12.0K0.00%+630+1,235.3%Added
US Bancorp403$7.25K0.00%+403New
California State Teachers Retirement System297$5.35K0.00%+297New
Parallel Advisors, LLC264$4.75K0.00%00.0%Unchanged
Allworth Financial LP161$2.90K0.00%00.0%Unchanged
Sterling Capital Management LLC76$1.37K0.00%+76New
SBI Securities Co., Ltd.68$1.22K0.00%00.0%Unchanged
Fortitude Family Office, LLC40$7200.00%00.0%Unchanged
Quarry LP29$5220.00%+29New
Advisor Group Holdings, Inc.26$4680.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd21$3780.00%+17+425.0%Added
National Bank of Canada3$540.00%+3New
Deep Track Capital, LP0$00.00%−453,686−100.0%Sold out
Alyeska Investment Group, L.P.0$00.00%−264,000−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−228,475−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−213,635−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−88,867−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−25,000−100.0%Sold out
Renaissance Technologies LLC0$00.00%−24,262−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−19,530−100.0%Sold out
Omers Administration Corp0$00.00%−17,800−100.0%Sold out
Algert Global LLC0$00.00%−13,806−100.0%Sold out
Verdad Advisers, LP0$00.00%−12,748−100.0%Sold out
Cannon Global Investment Management, LLC0$00.00%−10,200−100.0%Sold out