Crescent Biopharma, Inc.
CBIO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001253689
In the last 90 days, Crescent Biopharma, Inc. insiders filed 1 open-market purchase and 7 sales; 82 institutions reported holding it in 13F filings for Q2 2026, worth $532.6M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Crescent Biopharma, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 63
- +6 vs. Q4 2025
- Shares held
- 25.9M
- +2.39M (+10.1%) vs. Q4 2025
- Total value
- $476.6M
- +$197.4M (+70.7%) vs. Q4 2025
- New holders
- 17
- 18 more added
- Sold out
- 11
- 8 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting CBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 82 | $532.6M |
| Q1 2026 | 63 | $476.6M |
| Q4 2025 | 58 | $285.9M |
| Q3 2025 | 41 | $134.6M |
| Q2 2025 | 30 | $173.5M |
| Q1 2025 | 35 | $6.46M |
| Q4 2024 | 41 | $7.56M |
| Q3 2024 | 36 | $3.00M |
| Q2 2024 | 35 | $7.20M |
| Q1 2024 | 69 | $110.5M |
| Q4 2023 | 58 | $82.8M |
| Q3 2023 | 49 | $52.1M |
| Q2 2023 | 55 | $61.9M |
| Q1 2023 | 54 | $46.6M |
| Q4 2022 | 48 | $83.3M |
| Q3 2022 | 35 | $14.3M |
| Q2 2022 | 37 | $15.8M |
| Q1 2022 | 44 | $31.2M |
| Q4 2021 | 47 | $42.7M |
| Q3 2021 | 48 | $64.9M |
| Q2 2021 | 58 | $72.5M |
| Q1 2021 | 78 | $110.4M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Crescent Biopharma, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Caitong International Asset Management Co., Ltd | 4 | $73 | 0.00% | +4 | New |
| Advisor Group Holdings, Inc. | 26 | $477 | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 40 | $735 | 0.00% | +40 | New |
| Royal Bank of Canada | 51 | $1.00K | 0.00% | +31+155.0% | Added |
| SBI Securities Co., Ltd. | 68 | $1.25K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 161 | $2.96K | 0.00% | +161 | New |
| Parallel Advisors, LLC | 264 | $4.85K | 0.00% | +264 | New |
| Vanguard Global Advisers, LLC | 3,469 | $63.7K | 0.00% | +3,469 | New |
| Cannon Global Investment Management, LLC | 10,200 | $187.4K | 0.45% | +10,200 | New |
| Verdad Advisers, LP | 12,748 | $234.2K | 0.26% | +12,748 | New |
| Algert Global LLC | 13,806 | $253.6K | 0.00% | +13,806 | New |
| BNP Paribas Arbitrage, SA | 15,694 | $288.3K | 0.00% | +12,109+337.8% | Added |
| Northern Trust Corp | 17,229 | $316.5K | 0.00% | 00.0% | Unchanged |
| Omers Administration Corp | 17,800 | $327.0K | 0.00% | +6,200+53.4% | Added |
| Morgan Stanley | 18,577 | $341.3K | 0.00% | −8,944−32.5% | Reduced |
| Brevan Howard Capital Management LP | 19,530 | $358.8K | 0.00% | +19,530 | New |
| Citigroup Inc | 20,169 | $370.5K | 0.00% | +19,546+3,137.4% | Added |
| Quadrature Capital Ltd | 20,917 | $384.2K | 0.00% | +7,671+57.9% | Added |
| Renaissance Technologies LLC | 24,262 | $445.7K | 0.00% | −22,438−48.0% | Reduced |
| Manufacturers Life Insurance Company, The | 24,903 | $457.5K | 0.00% | 00.0% | Unchanged |
| Moore Capital Management, LP | 25,000 | $459.3K | 0.02% | 00.0% | Unchanged |
| Lighthouse Investment Partners, LLC | 25,000 | $459.3K | 0.02% | +25,000 | New |
| Bank of America Corp | 29,277 | $537.8K | 0.00% | +23,704+425.3% | Added |
| Barclays PLC | 30,189 | $554.6K | 0.00% | +30,189 | New |
| JPMorgan Chase & Co | 41,004 | $681.5K | 0.00% | +17,665+75.7% | Added |
| State Street Corp | 39,067 | $717.7K | 0.00% | +12,850+49.0% | Added |
| Vanguard Fiduciary Trust Co | 49,423 | $907.9K | 0.00% | +49,423 | New |
| ADAR1 Capital Management, LLC | 50,273 | $923.5K | 0.06% | −555,727−91.7% | Reduced |
| Woodline Partners LP | 74,000 | $1.36M | 0.01% | 00.0% | Unchanged |
| Burkehill Global Management, LP | 74,000 | $1.36M | 0.07% | 00.0% | Unchanged |
| UBS Group AG | 82,706 | $1.52M | 0.00% | +75,581+1,060.8% | Added |
| Stonepine Capital Management, LLC | 85,000 | $1.56M | 1.37% | −2,682−3.1% | Reduced |
| Hudson Bay Capital Management LP | 88,867 | $1.63M | 0.01% | +88,867 | New |
| Geode Capital Management, LLC | 104,221 | $1.92M | 0.00% | +13,142+14.4% | Added |
| BlackRock, Inc. | 115,725 | $2.13M | 0.00% | +6,495+5.9% | Added |
| Two Sigma Investments, LP | 115,828 | $2.13M | 0.00% | −9,396−7.5% | Reduced |
| Silverarc Capital Management, LLC | 130,500 | $2.40M | 0.28% | +130,500 | New |
| Jennison Associates LLC | 152,974 | $2.81M | 0.00% | +152,974 | New |
| Exome Asset Management LLC | 153,191 | $2.81M | 1.66% | +153,191 | New |
| Marshall Wace, LLP | 200,780 | $3.69M | 0.00% | +178,954+819.9% | Added |
| Perceptive Advisors LLC | 206,942 | $3.80M | 0.08% | −246,744−54.4% | Reduced |
| Susquehanna International Group, LLP | 213,635 | $3.92M | 0.01% | +156,587+274.5% | Added |
| Goldman Sachs Group Inc | 228,475 | $4.20M | 0.00% | +203,230+805.0% | Added |
| Alyeska Investment Group, L.P. | 264,000 | $4.85M | 0.01% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 300,000 | $5.51M | 0.01% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 303,551 | $5.58M | 0.00% | −34,574−10.2% | Reduced |
| Millennium Management LLC | 323,553 | $5.94M | 0.00% | +261,671+422.9% | Added |
| Remedium Capital Partners, LLC | 361,250 | $6.64M | 2.36% | 00.0% | Unchanged |
| RTW Investments, LP | 372,856 | $6.85M | 0.07% | 00.0% | Unchanged |
| NEXTBio Capital Management LP | 372,856 | $6.85M | 3.18% | 00.0% | Unchanged |
| Deep Track Capital, LP | 453,686 | $8.33M | 0.17% | 00.0% | Unchanged |
| Boxer Capital Management, LLC | 453,686 | $8.33M | 1.09% | 00.0% | Unchanged |
| Logos Global Management LP | 482,500 | $8.86M | 0.46% | −117,500−19.6% | Reduced |
| Vanguard Capital Management LLC | 801,395 | $14.7M | 0.00% | +801,395 | New |
| Tang Capital Management LLC | 1,160,000 | $21.3M | 1.08% | +287,602+33.0% | Added |
| Opaleye Management Inc. | 1,312,615 | $24.1M | 3.18% | +134,315+11.4% | Added |
| Vestal Point Capital, LP | 1,500,000 | $27.6M | 0.77% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 1,510,033 | $27.7M | 0.05% | +1,398,318+1,251.7% | Added |
| FCPM III Services B.V. | 1,677,852 | $30.8M | 4.27% | 00.0% | Unchanged |
| VR Adviser, LLC | 2,133,576 | $39.2M | 1.46% | 00.0% | Unchanged |
| Fairmount Funds Management LLC | 2,747,866 | $50.5M | 3.65% | 00.0% | Unchanged |
| BVF Inc | 2,748,763 | $50.5M | 1.61% | 00.0% | Unchanged |
| FMR LLC | 4,133,514 | $75.9M | 0.00% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 0 | $0 | 0.00% | −302,457−100.0% | Sold out |
| Heights Capital Management, Inc | 0 | $0 | 0.00% | −264,000−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −143,412−100.0% | Sold out |
| Blackstone Group Inc. | 0 | $0 | 0.00% | −75,614−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −64,244−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −32,500−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −22,965−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −13,083−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −409−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −4−100.0% | Sold out |
| Avion Wealth | 0 | $0 | 0.00% | −40−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |