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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Bicycle Therapeutics PLC as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
98
−11 vs. Q4 2025
Shares held
37.5M
−1.71M (−4.4%) vs. Q4 2025
Total value
$173.6M
−$103.3M (−37.3%) vs. Q4 2025
New holders
15
43 more added
Sold out
26
16 more reduced

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 98 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ1 2026: $173.6M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q4 2025.

Institutions holding BCYC in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
BNP PARIBAS ASSET MANAGEMENT Holding S.A.0$00.00%−568,225−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−297,247−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−146,100−100.0%Sold out
Walleye Capital LLC0$00.00%−111,659−100.0%Sold out
Bank of America Corp0$00.00%−96,401−100.0%Sold out
Monimus Capital Management, LP0$00.00%−93,840−100.0%Sold out
Nan Fung Group Holdings Ltd0$00.00%−68,943−100.0%Sold out
Quadrature Capital Ltd0$00.00%−46,728−100.0%Sold out
Harbor Capital Advisors, Inc.0$00.00%−40,486−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−21,548−100.0%Sold out
Simplex Trading, LLC0$00.00%−19,986−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−19,771−100.0%Sold out
The PNC Financial Services Group, Inc.0$00.00%−14,138−100.0%Sold out
JustInvest LLC0$00.00%−12,776−100.0%Sold out
Tocqueville Asset Management L.P.0$00.00%−12,600−100.0%Sold out
Raymond James Financial Inc0$00.00%−12,336−100.0%Sold out
Skopos Labs, Inc.0$00.00%−10,216−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−4,655−100.0%Sold out
FMR LLC0$00.00%−316−100.0%Sold out
Farther Finance Advisors, LLC0$00.00%−218−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−103−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−29−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−6−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−30,000−100.0%Sold out