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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Bicycle Therapeutics PLC as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
99
−11 vs. Q2 2025
Shares held
36.9M
−4.29M (−10.4%) vs. Q2 2025
Total value
$285.6M
−$718.9K (−0.3%) vs. Q2 2025
New holders
10
39 more added
Sold out
21
23 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 99 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ3 2025: $285.6M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q2 2025.

Institutions holding BCYC in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BNP PARIBAS ASSET MANAGEMENT Holding S.A.0$00.00%−1,041,456−100.0%Sold out
Tybourne Capital Management (HK) Ltd0$00.00%−993,743−100.0%Sold out
Woodline Partners LP0$00.00%−362,325−100.0%Sold out
AXA S.A.0$00.00%−280,152−100.0%Sold out
UBS Oconnor LLC0$00.00%−143,800−100.0%Sold out
Janney Montgomery Scott LLC0$00.00%−100,291−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−100,000−100.0%Sold out
Goldman Sachs Group Inc0$00.00%−52,265−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−42,729−100.0%Sold out
Paloma Partners Management Co0$00.00%−39,250−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−27,300−100.0%Sold out
Ausdal Financial Partners, Inc.0$00.00%−10,000−100.0%Sold out
Raymond James Financial Inc0$00.00%−1,933−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−1,517−100.0%Sold out
Group One Trading, L.P.0$00.00%−1,294−100.0%Sold out
Simplex Trading, LLC0$00.00%−1,241−100.0%Sold out
Skopos Labs, Inc.0$00.00%−923−100.0%Sold out
TD Waterhouse Canada Inc.0$00.00%−100−100.0%Sold out
Walleye Capital LLC0$00.00%−39−100.0%Sold out
CIBC Private Wealth Group, LLC0$00.00%−23−100.0%Sold out