Upstream Bio, Inc.
UPB- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0002022626
近 90 天，Upstream Bio, Inc. 內部人申報 0 筆公開市場買進、5 筆賣出；2026 年第 2 季末有 148 家機構在 13F 申報持有，市值合計 $3.50 億；沒有大師持有。
2026 年第 2 季 13F 持有人
Upstream Bio, Inc. 在 2026/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 148
- 較 2026 年第 1 季 +9 家
- 持有股數
- 5,057 萬
- 較 2026 年第 1 季 +568.9 萬 (+12.7%)
- 總市值
- $3.50 億
- 較 2026 年第 1 季 −$5,435 萬 (−13.4%)
- 新進機構
- 37
- 另有 65 家加碼
- 清倉機構
- 28
- 另有 28 家減碼
另有 1 家機構在 2026 年第 1 季持有、還沒有申報 2026 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 UPB 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 148 | $3.50 億 |
| 2026 年第 1 季 | 140 | $4.04 億 |
| 2025 年第 4 季 | 133 | $13.9 億 |
| 2025 年第 3 季 | 95 | $8.36 億 |
| 2025 年第 2 季 | 83 | $5.31 億 |
| 2025 年第 1 季 | 79 | $2.67 億 |
| 2024 年第 4 季 | 70 | $6.90 億 |
| 2024 年第 3 季 | 0 | $0 |
| 2024 年第 2 季 | 0 | $0 |
| 2024 年第 1 季 | 0 | $0 |
| 2023 年第 4 季 | 0 | $0 |
| 2023 年第 3 季 | 0 | $0 |
| 2023 年第 2 季 | 0 | $0 |
| 2023 年第 1 季 | 0 | $0 |
| 2022 年第 4 季 | 0 | $0 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2026 年第 2 季持有機構
每家機構持有 Upstream Bio, Inc. 的股數、市值與佔組合比重；股數變化跟 2026 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Covestor Ltd | 39 | $0 | 0.00% | +35+875.0% | 加碼 |
| Freestone Grove Partners LP | 1 | $7 | 0.00% | 00.0% | 不變 |
| National Bank of Canada | 1 | $7 | 0.00% | +1 | 新進 |
| JPL Wealth Management, LLC | 14 | $97 | 0.00% | +14 | 新進 |
| Clearstead Advisors, LLC | 15 | $105 | 0.00% | +15 | 新進 |
| Advisor Group Holdings, Inc. | 19 | $131 | 0.00% | −370−95.1% | 減碼 |
| Simplex Trading, LLC | 20 | $138 | 0.00% | +20 | 新進 |
| Silver Grove Financial Group, Inc. | 28 | $194 | 0.00% | +28 | 新進 |
| SJS Investment Consulting Inc. | 76 | $526 | 0.00% | +74+3,700.0% | 加碼 |
| N.E.W. Advisory Services LLC | 120 | $830 | 0.00% | 00.0% | 不變 |
| Essential Partners LLC | 146 | $1,010 | 0.00% | −256−63.7% | 減碼 |
| UMA Financial Services, Inc. | 160 | $1,108 | 0.00% | +160 | 新進 |
| IFP Advisors, Inc | 242 | $1,675 | 0.00% | +241+24,100.0% | 加碼 |
| US Bancorp | 264 | $1,827 | 0.00% | −326−55.3% | 減碼 |
| EverSource Wealth Advisors, LLC | 272 | $1,882 | 0.00% | +50+22.5% | 加碼 |
| Rothschild Investment LLC | 287 | $1,986 | 0.00% | +226+370.5% | 加碼 |
| Farther Finance Advisors, LLC | 353 | $2,443 | 0.00% | +272+335.8% | 加碼 |
| The PNC Financial Services Group, Inc. | 387 | $2,678 | 0.00% | +387 | 新進 |
| UBS Asset Management Americas Inc | 588 | $4,069 | 0.00% | 00.0% | 不變 |
| Sterling Capital Management LLC | 710 | $4,913 | 0.00% | −384−35.1% | 減碼 |
| Rockefeller Capital Management L.P. | 738 | $5,107 | 0.00% | 00.0% | 不變 |
| Allworth Financial LP | 778 | $5,384 | 0.00% | +515+195.8% | 加碼 |
| Quarry LP | 893 | $6,180 | 0.00% | +893 | 新進 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 965 | $6,678 | 0.00% | +488+102.3% | 加碼 |
| Royal Bank of Canada | 1,091 | $7,000 | 0.00% | +1,091 | 新進 |
| GF Fund Management Co. Ltd. | 1,145 | $7,923 | 0.00% | −58−4.8% | 減碼 |
| GAMMA Investing LLC | 1,164 | $8,055 | 0.00% | +449+62.8% | 加碼 |
| SRS Capital Advisors, Inc. | 1,771 | $1.23 萬 | 0.00% | +1,694+2,200.0% | 加碼 |
| Global Retirement Partners, LLC | 1,870 | $1.29 萬 | 0.00% | +1,870 | 新進 |
| Mirae Asset Global Investments Co., Ltd. | 2,434 | $1.68 萬 | 0.00% | −385−13.7% | 減碼 |
| Ameritas Investment Partners, Inc. | 2,741 | $1.90 萬 | 0.00% | 00.0% | 不變 |
| Vanguard Investments Australia, Ltd. | 4,096 | $2.83 萬 | 0.00% | 00.0% | 不變 |
| Nisa Investment Advisors, LLC | 4,278 | $2.96 萬 | 0.00% | −15,280−78.1% | 減碼 |
| Public Employees Retirement System of Ohio | 4,700 | $3.25 萬 | 0.00% | +4,700 | 新進 |
| Tower Research Capital LLC (TRC) | 4,788 | $3.31 萬 | 0.00% | +3,363+236.0% | 加碼 |
| Persistent Asset Partners Ltd | 4,855 | $3.36 萬 | 0.01% | −640−11.6% | 減碼 |
| New York State Common Retirement Fund | 5,200 | $3.60 萬 | 0.00% | +5,100+5,100.0% | 加碼 |
| KLP Kapitalforvaltning AS | 5,900 | $4.08 萬 | 0.00% | 00.0% | 不變 |
| China Universal Asset Management Co., Ltd. | 8,661 | $5.99 萬 | 0.00% | −929−9.7% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 9,456 | $6.54 萬 | 0.00% | 00.0% | 不變 |
| Ameriprise Financial Inc | 10,487 | $7.26 萬 | 0.00% | +10,487 | 新進 |
| Prelude Capital Management, LLC | 10,550 | $7.30 萬 | 0.01% | +10,550 | 新進 |
| Wealth Enhancement Advisory Services, LLC | 10,017 | $7.54 萬 | 0.00% | +10,017 | 新進 |
| HSBC Holdings PLC | 10,793 | $7.76 萬 | 0.00% | −629,533−98.3% | 減碼 |
| Canada Pension Plan Investment Board | 11,500 | $7.96 萬 | 0.00% | +11,500 | 新進 |
| STRS Ohio | 12,000 | $8.30 萬 | 0.00% | +2,200+22.4% | 加碼 |
| Engineers Gate Manager LP | 12,491 | $8.64 萬 | 0.00% | +12,491 | 新進 |
| Legal & General Group Plc | 12,561 | $8.69 萬 | 0.00% | +2,952+30.7% | 加碼 |
| Vanguard Global Advisers, LLC | 13,059 | $9.04 萬 | 0.00% | 00.0% | 不變 |
| Mercer Global Advisors Inc | 13,352 | $9.24 萬 | 0.00% | +13,352 | 新進 |
| Jane Street Group, LLC | 15,594 | $10.8 萬 | 0.00% | +15,594 | 新進 |
| Manufacturers Life Insurance Company, The | 15,735 | $10.9 萬 | 0.00% | +397+2.6% | 加碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 16,217 | $11.2 萬 | 0.00% | +609+3.9% | 加碼 |
| State of Wisconsin Investment Board | 17,065 | $11.8 萬 | 0.00% | −24,606−59.0% | 減碼 |
| Entropy Technologies, LP | 17,542 | $12.1 萬 | 0.00% | −5,794−24.8% | 減碼 |
| Quadrature Capital Ltd | 17,988 | $12.4 萬 | 0.00% | +17,988 | 新進 |
| Shay Capital LLC | 18,000 | $12.5 萬 | 0.01% | +8,000+80.0% | 加碼 |
| Diadema Partners LP | 19,093 | $13.2 萬 | 0.05% | −2,516−11.6% | 減碼 |
| Ieq Capital, LLC | 19,535 | $13.5 萬 | 0.00% | +19,535 | 新進 |
| Winton Group Ltd | 19,800 | $13.7 萬 | 0.00% | +19,800 | 新進 |
| SEI Investments Co | 20,026 | $13.9 萬 | 0.00% | +20,026 | 新進 |
| SG Americas Securities, LLC | 20,338 | $14.1 萬 | 0.00% | +20,338 | 新進 |
| MetLife Investment Management | 20,852 | $14.4 萬 | 0.00% | +1,472+7.6% | 加碼 |
| Verdad Advisers, LP | 21,810 | $15.1 萬 | 0.14% | +21,810 | 新進 |
| Los Angeles Capital Management LLC | 22,385 | $15.5 萬 | 0.00% | +22,385 | 新進 |
| Graham Capital Management, L.P. | 22,508 | $15.6 萬 | 0.00% | +22,508 | 新進 |
| Vanguard Asset Management, Ltd | 22,724 | $15.7 萬 | 0.00% | +13,474+145.7% | 加碼 |
| DnB Asset Management AS | 23,600 | $16.3 萬 | 0.00% | +85+0.4% | 加碼 |
| nVerses Capital, LLC | 24,029 | $16.6 萬 | 0.26% | +24,029 | 新進 |
| Axq Capital, LP | 27,068 | $18.7 萬 | 0.02% | −435−1.6% | 減碼 |
| Quantbot Technologies LP | 28,178 | $19.5 萬 | 0.01% | +27,515+4,150.1% | 加碼 |
| Price T Rowe Associates Inc | 28,058 | $19.5 萬 | 0.00% | +1,624+6.1% | 加碼 |
| Creative Planning | 28,483 | $19.7 萬 | 0.00% | +17,633+162.5% | 加碼 |
| Barclays PLC | 29,208 | $20.2 萬 | 0.00% | +4,488+18.2% | 加碼 |
| Wells Fargo & Company | 29,497 | $20.4 萬 | 0.00% | +11,095+60.3% | 加碼 |
| Mariner, LLC | 33,141 | $22.9 萬 | 0.00% | +5,827+21.3% | 加碼 |
| Stonepine Capital Management, LLC | 33,432 | $23.1 萬 | 0.18% | −1,568−4.5% | 減碼 |
| California State Teachers Retirement System | 38,634 | $26.7 萬 | 0.00% | −1,027−2.6% | 減碼 |
| Citigroup Inc | 40,339 | $27.9 萬 | 0.00% | +35,284+698.0% | 加碼 |
| ExodusPoint Capital Management, LP | 41,045 | $28.4 萬 | 0.00% | −50,386−55.1% | 減碼 |
| Two Sigma Investments, LP | 42,325 | $29.3 萬 | 0.00% | +42,325 | 新進 |
| Rhumbline Advisers | 42,384 | $29.3 萬 | 0.00% | +1,181+2.9% | 加碼 |
| Allspring Global Investments Holdings, LLC | 43,182 | $29.9 萬 | 0.00% | +43,182 | 新進 |
| Russell Investments Group, Ltd. | 47,543 | $32.9 萬 | 0.00% | +43,896+1,203.6% | 加碼 |
| Swiss National Bank | 48,100 | $33.3 萬 | 0.00% | 00.0% | 不變 |
| Brevan Howard Capital Management LP | 50,369 | $34.9 萬 | 0.00% | +50,369 | 新進 |
| Invesco Ltd. | 53,397 | $37.0 萬 | 0.00% | +12,887+31.8% | 加碼 |
| Virtus Investment Advisers, Inc. | 53,638 | $37.1 萬 | 0.09% | +43,592+433.9% | 加碼 |
| Quantinno Capital Management LP | 54,838 | $37.9 萬 | 0.00% | +5,449+11.0% | 加碼 |
| Alps Advisors Inc | 55,228 | $38.2 萬 | 0.00% | +11,236+25.5% | 加碼 |
| Simplify Asset Management Inc. | 62,113 | $43.0 萬 | 0.01% | −15,680−20.2% | 減碼 |
| Alliancebernstein L.P. | 51,680 | $46.5 萬 | 0.00% | +20,670+66.7% | 加碼 |
| Gsa Capital Partners LLP | 69,348 | $48.0 萬 | 0.03% | +30,116+76.8% | 加碼 |
| Man Group plc | 73,823 | $51.1 萬 | 0.00% | +52,669+249.0% | 加碼 |
| American Century Companies Inc | 78,194 | $54.1 萬 | 0.00% | −9,430−10.8% | 減碼 |
| Nuveen, LLC | 84,770 | $58.7 萬 | 0.00% | +9,234+12.2% | 加碼 |
| Bank of New York Mellon Corp | 85,747 | $59.3 萬 | 0.00% | +4,364+5.4% | 加碼 |
| Algert Global LLC | 118,630 | $82.1 萬 | 0.01% | +118,630 | 新進 |
| EntryPoint Capital, LLC | 129,446 | $89.6 萬 | 0.22% | +55,878+76.0% | 加碼 |
| Renaissance Technologies LLC | 131,300 | $90.9 萬 | 0.00% | +69,200+111.4% | 加碼 |