Upstream Bio, Inc.
UPB- 交易所
- Nasdaq
- 產業
- Pharmaceutical Preparations
- SEC CIK
- 0002022626
近 90 天，Upstream Bio, Inc. 內部人申報 0 筆公開市場買進、5 筆賣出；2026 年第 2 季末有 148 家機構在 13F 申報持有，市值合計 $3.50 億；沒有大師持有。
2025 年第 2 季 13F 持有人
Upstream Bio, Inc. 在 2025/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 83
- 較 2025 年第 1 季 +4 家
- 持有股數
- 4,835 萬
- 較 2025 年第 1 季 +207.4 萬 (+4.5%)
- 總市值
- $5.31 億
- 較 2025 年第 1 季 +$2.64 億 (+98.9%)
- 新進機構
- 14
- 另有 41 家加碼
- 清倉機構
- 10
- 另有 13 家減碼
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 UPB 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 148 | $3.50 億 |
| 2026 年第 1 季 | 140 | $4.04 億 |
| 2025 年第 4 季 | 133 | $13.9 億 |
| 2025 年第 3 季 | 95 | $8.36 億 |
| 2025 年第 2 季 | 83 | $5.31 億 |
| 2025 年第 1 季 | 79 | $2.67 億 |
| 2024 年第 4 季 | 70 | $6.90 億 |
| 2024 年第 3 季 | 0 | $0 |
| 2024 年第 2 季 | 0 | $0 |
| 2024 年第 1 季 | 0 | $0 |
| 2023 年第 4 季 | 0 | $0 |
| 2023 年第 3 季 | 0 | $0 |
| 2023 年第 2 季 | 0 | $0 |
| 2023 年第 1 季 | 0 | $0 |
| 2022 年第 4 季 | 0 | $0 |
| 2022 年第 3 季 | 0 | $0 |
| 2022 年第 2 季 | 0 | $0 |
| 2022 年第 1 季 | 0 | $0 |
| 2021 年第 4 季 | 0 | $0 |
| 2021 年第 3 季 | 0 | $0 |
| 2021 年第 2 季 | 0 | $0 |
| 2021 年第 1 季 | 0 | $0 |
2025 年第 2 季持有機構
每家機構持有 Upstream Bio, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| FMR LLC | 7,936,880 | $8,715 萬 | 0.00% | +681,021+9.4% | 加碼 |
| OrbiMed Advisors LLC | 5,693,589 | $6,252 萬 | 1.57% | 00.0% | 不變 |
| Altshuler Shaham Ltd | 3,394,441 | $3,727 萬 | 1.18% | +159,148+4.9% | 加碼 |
| Decheng Capital LLC | 3,285,293 | $3,607 萬 | 9.11% | 00.0% | 不變 |
| TCG Crossover Management, LLC | 2,801,763 | $3,076 萬 | 3.51% | 00.0% | 不變 |
| Enavate Sciences GP, LLC | 2,459,703 | $2,701 萬 | 15.30% | 00.0% | 不變 |
| Bain Capital Life Sciences Investors, LLC | 2,439,538 | $2,679 萬 | 3.35% | +144,216+6.3% | 加碼 |
| VR Adviser, LLC | 2,295,319 | $2,520 萬 | 1.89% | 00.0% | 不變 |
| Vanguard Group Inc | 2,170,833 | $2,384 萬 | 0.00% | +1,263,807+139.3% | 加碼 |
| BlackRock, Inc. | 2,096,506 | $2,302 萬 | 0.00% | +910,738+76.8% | 加碼 |
| Omega Fund Management, LLC | 2,036,293 | $2,236 萬 | 14.48% | 00.0% | 不變 |
| Samsara BioCapital, LLC | 1,443,231 | $1,585 萬 | 3.24% | −623,915−30.2% | 減碼 |
| Deep Track Capital, LP | 1,442,767 | $1,584 萬 | 0.51% | −856,800−37.3% | 減碼 |
| Wellington Management Group LLP | 1,225,295 | $1,345 萬 | 0.00% | −88,162−6.7% | 減碼 |
| Norges Bank | 969,916 | $1,065 萬 | 0.00% | 00.0% | 不變 |
| Siren, L.L.C. | 788,450 | $865.7 萬 | 0.45% | 00.0% | 不變 |
| Parkman Healthcare Partners LLC | 715,504 | $785.6 萬 | 0.91% | +481,941+206.3% | 加碼 |
| Geode Capital Management, LLC | 646,635 | $710.1 萬 | 0.00% | +235,958+57.5% | 加碼 |
| Nantahala Capital Management, LLC | 594,971 | $653.3 萬 | 0.46% | 00.0% | 不變 |
| Woodline Partners LP | 558,252 | $613.0 萬 | 0.03% | +1,189+0.2% | 加碼 |
| State Street Corp | 481,375 | $528.5 萬 | 0.00% | +185,788+62.9% | 加碼 |
| Schonfeld Strategic Advisors LLC | 365,790 | $401.6 萬 | 0.03% | +187,806+105.5% | 加碼 |
| Great Point Partners LLC | 300,000 | $329.4 萬 | 2.14% | 00.0% | 不變 |
| Marshall Wace, LLP | 290,526 | $319.0 萬 | 0.00% | −14,437−4.7% | 減碼 |
| UBS Group AG | 232,887 | $255.7 萬 | 0.00% | +101,336+77.0% | 加碼 |
| Northern Trust Corp | 229,303 | $251.8 萬 | 0.00% | +91,532+66.4% | 加碼 |
| Lynx1 Capital Management LP | 219,247 | $240.7 萬 | 0.70% | 00.0% | 不變 |
| Charles Schwab Investment Management Inc | 178,253 | $195.7 萬 | 0.00% | +46,080+34.9% | 加碼 |
| Velan Capital Investment Management LP | 107,000 | $117.5 萬 | 1.18% | 00.0% | 不變 |
| Morgan Stanley | 99,308 | $109.0 萬 | 0.00% | +47,917+93.2% | 加碼 |
| Barclays PLC | 96,990 | $106.5 萬 | 0.00% | +71,997+288.1% | 加碼 |
| Alyeska Investment Group, L.P. | 85,000 | $93.3 萬 | 0.00% | 00.0% | 不變 |
| Bank of New York Mellon Corp | 79,766 | $87.6 萬 | 0.00% | +42,854+116.1% | 加碼 |
| Nuveen, LLC | 73,936 | $81.2 萬 | 0.00% | +51,350+227.4% | 加碼 |
| Rhumbline Advisers | 48,066 | $52.8 萬 | 0.00% | +34,739+260.7% | 加碼 |
| Susquehanna International Group, LLP | 42,263 | $46.4 萬 | 0.00% | +20,999+98.8% | 加碼 |
| Verition Fund Management LLC | 33,505 | $36.8 萬 | 0.00% | +33,505 | 新進 |
| AQR Capital Management LLC | 29,752 | $32.7 萬 | 0.00% | +10,930+58.1% | 加碼 |
| Alps Advisors Inc | 28,976 | $31.8 萬 | 0.00% | −10,103−25.9% | 減碼 |
| Alliancebernstein L.P. | 24,560 | $27.0 萬 | 0.00% | −1,066,626−97.7% | 減碼 |
| Deutsche Bank AG | 23,403 | $25.7 萬 | 0.00% | +8,211+54.0% | 加碼 |
| Wells Fargo & Company | 22,364 | $24.6 萬 | 0.00% | +13,114+141.8% | 加碼 |
| American Century Companies Inc | 22,362 | $24.6 萬 | 0.00% | +22,362 | 新進 |
| MetLife Investment Management | 21,691 | $23.8 萬 | 0.00% | +10,657+96.6% | 加碼 |
| Intech Investment Management LLC | 21,290 | $23.4 萬 | 0.00% | +6,005+39.3% | 加碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 19,084 | $21.0 萬 | 0.00% | +8,788+85.4% | 加碼 |
| Bank of America Corp | 18,031 | $19.8 萬 | 0.00% | +7,500+71.2% | 加碼 |
| Price T Rowe Associates Inc | 17,448 | $19.2 萬 | 0.00% | +17,448 | 新進 |
| JPMorgan Chase & Co | 16,469 | $18.1 萬 | 0.00% | +1,275+8.4% | 加碼 |
| Invesco Ltd. | 16,300 | $17.9 萬 | 0.00% | +985+6.4% | 加碼 |
| Commonwealth Equity Services, LLC | 15,526 | $17.0 萬 | 0.00% | +15,526 | 新進 |
| Creative Planning | 14,030 | $15.4 萬 | 0.00% | +14,030 | 新進 |
| Manufacturers Life Insurance Company, The | 13,190 | $14.5 萬 | 0.00% | +13,190 | 新進 |
| Citigroup Inc | 11,695 | $12.8 萬 | 0.00% | −6,483−35.7% | 減碼 |
| Quantinno Capital Management LP | 10,614 | $11.7 萬 | 0.00% | −4,611−30.3% | 減碼 |
| Virtus Investment Advisers, Inc. | 8,134 | $8.93 萬 | 0.03% | +8,134 | 新進 |
| Police & Firemen's Retirement System of New Jersey | 7,833 | $8.60 萬 | 0.00% | +4,483+133.8% | 加碼 |
| New York State Common Retirement Fund | 4,700 | $5.16 萬 | 0.00% | 00.0% | 不變 |
| Ameritas Investment Partners, Inc. | 3,558 | $3.91 萬 | 0.00% | +1,736+95.3% | 加碼 |
| CWM, LLC | 3,312 | $3.60 萬 | 0.00% | +1,716+107.5% | 加碼 |
| Legal & General Group Plc | 3,174 | $3.49 萬 | 0.00% | +1,440+83.0% | 加碼 |
| BNP Paribas Arbitrage, SA | 3,097 | $3.40 萬 | 0.00% | +2,158+229.8% | 加碼 |
| Tower Research Capital LLC (TRC) | 3,051 | $3.35 萬 | 0.00% | +1,469+92.9% | 加碼 |
| Royal Bank of Canada | 3,090 | $3.30 萬 | 0.00% | +2,258+271.4% | 加碼 |
| California State Teachers Retirement System | 2,174 | $2.39 萬 | 0.00% | +884+68.5% | 加碼 |
| STRS Ohio | 1,800 | $1.98 萬 | 0.00% | −1,400−43.8% | 減碼 |
| Sterling Capital Management LLC | 941 | $1.03 萬 | 0.00% | +804+586.9% | 加碼 |
| GAMMA Investing LLC | 693 | $7,609 | 0.00% | +100+16.9% | 加碼 |
| US Bancorp | 659 | $7,236 | 0.00% | +97+17.3% | 加碼 |
| Amalgamated Bank | 594 | $7,000 | 0.00% | 00.0% | 不變 |
| Versant Capital Management, Inc | 558 | $6,127 | 0.00% | −57−9.3% | 減碼 |
| EverSource Wealth Advisors, LLC | 309 | $3,393 | 0.00% | +174+128.9% | 加碼 |
| Caitong International Asset Management Co., Ltd | 224 | $2,460 | 0.00% | +224 | 新進 |
| Clearstead Advisors, LLC | 163 | $1,790 | 0.00% | +163 | 新進 |
| Russell Investments Group, Ltd. | 147 | $1,614 | 0.00% | +147 | 新進 |
| Essential Partners LLC | 97 | $1,065 | 0.00% | +97 | 新進 |
| Nisa Investment Advisors, LLC | 96 | $1,054 | 0.00% | −40−29.4% | 減碼 |
| Allworth Financial LP | 66 | $725 | 0.00% | −119−64.3% | 減碼 |
| Signaturefd, LLC | 49 | $538 | 0.00% | −41−45.6% | 減碼 |
| True Wealth Design, LLC | 31 | $341 | 0.00% | +15+93.8% | 加碼 |
| Advisor Group Holdings, Inc. | 42 | $257 | 0.00% | +42 | 新進 |
| Parallel Advisors, LLC | 2 | $22 | 0.00% | +2 | 新進 |
| IFP Advisors, Inc | 1 | $11 | 0.00% | +1 | 新進 |
| Millennium Management LLC | 0 | $0 | 0.00% | −61,796−100.0% | 清倉 |
| EcoR1 Capital, LLC | 0 | $0 | 0.00% | −60,000−100.0% | 清倉 |
| Goldman Sachs Group Inc | 0 | $0 | 0.00% | −32,955−100.0% | 清倉 |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −21,789−100.0% | 清倉 |
| ADAR1 Capital Management, LLC | 0 | $0 | 0.00% | −15,000−100.0% | 清倉 |
| XTX Topco Ltd | 0 | $0 | 0.00% | −12,731−100.0% | 清倉 |
| Walleye Capital LLC | 0 | $0 | 0.00% | −10,000−100.0% | 清倉 |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −8,533−100.0% | 清倉 |
| UMA Financial Services, Inc. | 0 | $0 | 0.00% | −69−100.0% | 清倉 |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −12−100.0% | 清倉 |